Diagnostic Accuracy of Noninvasive Tests to Evaluate Bladder Outlet Obstruction in Men: Detrusor Wall Thickness, Uroflowmetry, Postvoid Residual Urine, and Prostate Volume

@article{citeulike:1523312, abstract = {Objectives The aim of this prospective study was to compare the diagnostic accuracy of detrusor wall thickness (DWT), free uroflowmetry, postvoid residual urine, and prostate volume (index tests) with pressure-flow studies (reference standard) to detect bladder outlet obstruction (BOO) in men.Methods During a 2-yr period, men older than 40 yr with lower urinary tract symptoms and/or prostatic enlargement had the following tests: ultrasound measurements of DWT, free uroflowmetry (Qmax, Qave), postvoid residual urine, and prostate volume. Pressure-flow studies were used to divide obstructed from nonobstructed bladders.Results One hundred sixty men between 40-89 yr of age (median: 62 yr) were included in the study; 75 patients (46.9\%) had BOO according to pressure-flow studies. The results of all investigated index tests differed significantly between obstructed and nonobstructed men. DWT was the most accurate test to determine BOO: the positive predictive value was 94\%, specificity 95\%, and the area under the curve of ROC analysis 0.93. There was an agreement of 89\% between the results of DWT measurement and pressure-flow studies.Conclusions Measurements of DWT can detect BOO better than free uroflowmetry, postvoid residual urine, or prostate volume. In clinical routine, DWT measurements can be used to judge BOO noninvasively.}, author = {Oelke, Matthias and Hofner, Klaus and Jonas, Udo and de La and Ubbink, Dirk T. and Wijkstra, Hessel }, citeulike-article-id = {1523312}, doi = {10.1016/j.eururo.2006.12.023}, journal = {European Urology}, keywords = {bladder\_neck\_obstruction, diagnosis, fulltext, review}, posted-at = {2007-07-31 02:06:05}, priority = {4}, title = {Diagnostic Accuracy of Noninvasive Tests to Evaluate Bladder Outlet Obstruction in Men: Detrusor Wall Thickness, Uroflowmetry, Postvoid Residual Urine, and Prostate Volume}, url = {http://dx.doi.org/10.1016/j.eururo.2006.12.023}, volume = {In Press, Corrected Proof} }

TY - JOUR ID - citeulike:1523312 L3 - citeulike-article-id:1523312 TI - Diagnostic Accuracy of Noninvasive Tests to Evaluate Bladder Outlet Obstruction in Men: Detrusor Wall Thickness, Uroflowmetry, Postvoid Residual Urine, and Prostate Volume JF - European Urology VL - In Press, Corrected Proof N2 - Objectives The aim of this prospective study was to compare the diagnostic accuracy of detrusor wall thickness (DWT), free uroflowmetry, postvoid residual urine, and prostate volume (index tests) with pressure-flow studies (reference standard) to detect bladder outlet obstruction (BOO) in men.Methods During a 2-yr period, men older than 40 yr with lower urinary tract symptoms and/or prostatic enlargement had the following tests: ultrasound measurements of DWT, free uroflowmetry (Qmax, Qave), postvoid residual urine, and prostate volume. Pressure-flow studies were used to divide obstructed from nonobstructed bladders.Results One hundred sixty men between 40-89 yr of age (median: 62 yr) were included in the study; 75 patients (46.9%) had BOO according to pressure-flow studies. The results of all investigated index tests differed significantly between obstructed and nonobstructed men. DWT was the most accurate test to determine BOO: the positive predictive value was 94%, specificity 95%, and the area under the curve of ROC analysis 0.93. There was an agreement of 89% between the results of DWT measurement and pressure-flow studies.Conclusions Measurements of DWT can detect BOO better than free uroflowmetry, postvoid residual urine, or prostate volume. In clinical routine, DWT measurements can be used to judge BOO noninvasively. KW - bladder_neck_obstruction KW - diagnosis KW - fulltext KW - review AU - Oelke, Matthias AU - Hofner, Klaus AU - Jonas, Udo AU - de La AU - Ubbink, Dirk AU - Wijkstra, Hessel UR - http://dx.doi.org/10.1016/j.eururo.2006.12.023 ER -