Tat-SIRT1 Tango.

by: Dalibor Blazek, B Matija M Peterlin

Mol Cell, Vol. 29, No. 5. (14 March 2008), pp. 539-540.

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Abstract

In a recent issue of Cell Host & Microbe, Kwon et al. (2008) report that the human immunodeficiency virus (HIV) transactivator Tat inhibits the SIRT1 deacetylase, resulting in increased acetylation of the NF-kappaB p65 subunit and subsequently in T cell hyperactivation.

@article{citeulike:2566534, abstract = {In a recent issue of Cell Host \& Microbe, Kwon et al. (2008) report that the human immunodeficiency virus (HIV) transactivator Tat inhibits the SIRT1 deacetylase, resulting in increased acetylation of the NF-kappaB p65 subunit and subsequently in T cell hyperactivation.}, address = {Department of Medicine, Rosalind Russell Medical Research Center, University of California, San Francisco, San Francisco, CA 94143-0703, USA; Department of Microbiology and Immunology, Rosalind Russell Medical Research Center, University of California, San Francisco, San Francisco, CA 94143-0703, USA.}, author = {Blazek, Dalibor and Peterlin, B Matija M. }, citeulike-article-id = {2566534}, doi = {http://dx.doi.org/10.1016/j.molcel.2008.02.007}, issn = {1097-2765}, journal = {Mol Cell}, keywords = {review, sirt1}, month = {March}, number = {5}, pages = {539--540}, posted-at = {2008-03-20 13:18:30}, priority = {2}, title = {Tat-SIRT1 Tango.}, url = {http://dx.doi.org/10.1016/j.molcel.2008.02.007}, volume = {29}, year = {2008} }

RIS record

TY - JOUR ID - citeulike:2566534 L3 - citeulike-article-id:2566534 N2 - In a recent issue of Cell Host & Microbe, Kwon et al. (2008) report that the human immunodeficiency virus (HIV) transactivator Tat inhibits the SIRT1 deacetylase, resulting in increased acetylation of the NF-kappaB p65 subunit and subsequently in T cell hyperactivation. IS - 5 JF - Mol Cell SN - 1097-2765 AD - Department of Medicine, Rosalind Russell Medical Research Center, University of California, San Francisco, San Francisco, CA 94143-0703, USA; Department of Microbiology and Immunology, Rosalind Russell Medical Research Center, University of California, San Francisco, San Francisco, CA 94143-0703, USA. EP - 540 TI - Tat-SIRT1 Tango. VL - 29 SP - 539 KW - review KW - sirt1 AU - Blazek, Dalibor AU - Peterlin, B Matija PY - 2008/03/14/ UR - http://dx.doi.org/10.1016/j.molcel.2008.02.007 ER -

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