In Vino Veritas: A Tale of Two Sirt1s?

@article{citeulike:2033117, abstract = {Resveratrol increases life span in lower organisms by activating the NAD+-dependent histone deacetylase Sirt1. Studies by Lagouge et al. (2006) and Baur et al. (2006) now show that resveratrol promotes longevity and improves glucose homeostasis in mice by stimulating the Sirt1-mediated deacetylation of the transcriptional coactivator PGC-1[alpha].}, author = {Koo, Seung-Hoi and Montminy, Marc }, citeulike-article-id = {2033117}, doi = {http://dx.doi.org/10.1016/j.cell.2006.11.034}, journal = {Cell}, keywords = {aging, resveratrol, review, sirt1}, month = {December}, number = {6}, pages = {1091--1093}, posted-at = {2007-11-30 22:45:00}, priority = {2}, title = {In Vino Veritas: A Tale of Two Sirt1s?}, url = {http://dx.doi.org/10.1016/j.cell.2006.11.034}, volume = {127}, year = {2006} }

TY - JOUR ID - citeulike:2033117 L3 - citeulike-article-id:2033117 TI - In Vino Veritas: A Tale of Two Sirt1s? JF - Cell VL - 127 IS - 6 SP - 1091 EP - 1093 N2 - Resveratrol increases life span in lower organisms by activating the NAD+-dependent histone deacetylase Sirt1. Studies by Lagouge et al. (2006) and Baur et al. (2006) now show that resveratrol promotes longevity and improves glucose homeostasis in mice by stimulating the Sirt1-mediated deacetylation of the transcriptional coactivator PGC-1[alpha]. KW - aging KW - resveratrol KW - review KW - sirt1 AU - Koo, Seung-Hoi AU - Montminy, Marc PY - 2006/12/15/ UR - http://dx.doi.org/10.1016/j.cell.2006.11.034 ER -