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zhleis library [315 articles]

Neue Artikel in zhleis Bibliothek.
  • The Ongoing Saga of Sirtuins and Aging
    Cell Metabolism, Vol. 8, No. 1. (2 July 2008), pp. 4-5.
    by Matt Kaeberlein
    posted to sirt1 review aging by zhlei on 2008-07-02 21:42:02 as **
  • SirT1 Inhibition Reduces IGF-I/IRS-2/Ras/ERK1/2 Signaling and Protects Neurons
    Cell Metabolism, Vol. 8, No. 1. (2 July 2008), pp. 38-48.
    by Ying Li, Wei Xu, Michael W Mcburney, Valter D Longo
    posted to sirtuin sirt1 igf1 by zhlei on 2008-07-02 21:39:51 as **
  • Epigenetic control of rDNA loci in response to intracellular energy status.
    Cell, Vol. 133, No. 4. (16 May 2008), pp. 627-639.
    by A Murayama, K Ohmori, A Fujimura, H Minami, K Yasuzawa-Tanaka, T Kuroda, S Oie, H Daitoku, M Okuwaki, K Nagata, A Fukamizu, K Kimura, T Shimizu, J Yanagisawa
    posted to sirtuin sir1 rdna by zhlei on 2008-07-02 21:02:28 as ** along with 1 person slevy03
  • A Metabolic Throttle Regulates the Epigenetic State of rDNA
    Cell, Vol. 133, No. 4. (16 May 2008), pp. 577-580.
    by Ingrid Grummt, Andreas G Ladurner
    posted to sirtuin sirt1 review rdna by zhlei on 2008-07-02 20:59:30 as ** along with 1 person slevy03
  • The FACT Spt16 "peptidase" domain is a histone H3-H4 binding module
    Proceedings of the National Academy of Sciences (25 June 2008), 0712293105.
    by Tobias Stuwe, Michael Hothorn, Erwan Lejeune, Vladimir Rybin, Miriam Bortfeld, Klaus Scheffzek, Andreas G Ladurner
    posted to spt16 fact by zhlei on 2008-07-01 02:13:08 as **
  • Sirtuins: Novel targets for metabolic disease in drug development
    Biochemical and Biophysical Research Communications, Vol. In Press, Corrected Proof
    by Wei-Jian Jiang
    posted to sirtuin review by zhlei on 2008-06-30 20:51:10 as **
  • WHY DO CANCERS HAVE HIGH AEROBIC GLYCOLYSIS?
    Nat Rev Cancer, Vol. 4, No. 11. (November 2004), pp. 891-899.
    by Robert A Gatenby, Robert J Gillies
    posted to glycolysis cancer by zhlei on 2008-06-20 20:18:11 as ** along with 1 person laurabailey
  • An elaborate pathway required for Ras-mediated epigenetic silencing
    Nature, Vol. 449, No. 7165., pp. 1073-1077.
    by Claude Gazin, Narendra Wajapeyee, Stephane Gobeil, Ching-Man Virbasius, Michael R Green
    posted to sirt6 chip by zhlei on 2008-06-20 15:55:22 as ** along with 2 people jackjackjjj SciNika
  • An embryoprotective role for glucose-6-phosphate dehydrogenase in developmental oxidative stress and chemical teratogenesis.
    The FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 14, No. 1. (January 2000), pp. 111-127.
    by CJ Nicol, J Zielenski, LC Tsui, PG Wells
    posted to g6pd by zhlei on 2008-06-05 22:26:26 as **
  • SIRT1 regulates hepatocyte lipid metabolism through activating AMP-activated protein kinase.
    The Journal of biological chemistry (14 May 2008)
    by Xiuyun Hou, Shanqin Xu, Karlene A A Maitland-Toolan, Kaori Sato, Bingbing Jiang, Yasuo Ido, Fan Lan, Kenneth Walsh, Michel Wierzbicki, Tony J J Verbeuren, Richard A A Cohen
    posted to sirt1 metabolism by zhlei on 2008-05-18 22:10:53 as ** along with 1 person jyuh
  • SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin
    Nature (12 March 2008)
    by Eriko Michishita, Ronald A Mccord, Elisabeth Berber, Mitomu Kioi, Hesed Padilla-Nash, Mara Damian, Peggie Cheung, Rika Kusumoto, Tiara LA Kawahara, Carl J Barrett, Howard Y Chang, Vilhelm A Bohr, Thomas Ried, Or Gozani, Katrin F Chua
    posted to telomere sirtuin sirt6 histone h3k9 acetylation by zhlei on 2008-05-01 23:19:25 as ** along with 1 person biomcgary
  • AKT/PKB signaling: navigating downstream.
    Cell, Vol. 129, No. 7. (29 June 2007), pp. 1261-1274.
    by BD Manning, LC Cantley
    posted to review akt by zhlei on 2008-04-29 18:21:18 as ** along with 3 people voldog jyuh lisa1
  • Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks.
    J Cell Biol, Vol. 173, No. 2. (24 April 2006), pp. 195-206.
    by S Bekker-Jensen, C Lukas, R Kitagawa, F Melander, MB Kastan, J Bartek, J Lukas
    posted to dna-pk dna-damage atr atm by zhlei on 2008-04-29 17:59:25 as ** along with 1 person DNAReplication
  • Sir2 Deacetylates Histone H3 Lysine 56 to Regulate Telomeric Heterochromatin Structure in Yeast
    Molecular Cell, Vol. 27, No. 6. (21 September 2007), pp. 890-900.
    by Feng Xu, Qiongyi Zhang, Kangling Zhang, Wei Xie, Michael Grunstein
    posted to yeast telomere sir2 heterochromatin by zhlei on 2008-04-28 23:06:15 as ** along with 1 person onufriev
  • PKB[alpha]/Akt1 Acts Downstream of DNA-PK in the DNA Double-Strand Break Response and Promotes Survival
    Molecular Cell, Vol. 30, No. 2. (25 April 2008), pp. 203-213.
    by Lana Bozulic, Banu Surucu, Debby Hynx, Brian A Hemmings
    posted to dna-damage akt by zhlei on 2008-04-28 23:04:28 as **
  • The DNA damage response pathways: at the crossroad of protein modifications.
    Cell Res, Vol. 18, No. 1. (January 2008), pp. 8-16.
    by MS Huen, J Chen
    posted to dna-damage by zhlei on 2008-04-25 19:23:58 as ** along with 1 person jyuh
  • Sirt7 Increases Stress Resistance of Cardiomyocytes and Prevents Apoptosis and Inflammatory Cardiomyopathy in Mice
    Circ Res, Vol. 102, No. 6. (28 March 2008), pp. 703-710.
    by Olesya Vakhrusheva, Christian Smolka, Praveen Gajawada, Sawa Kostin, Thomas Boettger, Thomas Kubin, Thomas Braun, Eva Bober
    posted to sirt7 by zhlei on 2008-04-25 16:06:51 as **
  • Mammalian Sir2 homolog SIRT7 is an activator of RNA polymerase I transcription
    Genes Dev., Vol. 20, No. 9. (1 May 2006), pp. 1075-1080.
    by Ethan Ford, Renate Voit, Gregory Liszt, Cornelia Magin, Ingrid Grummt, Leonard Guarente
    posted to sirtuin sirt7 by zhlei on 2008-04-25 00:37:55 as **
  • SIRT3, a mitochondrial sirtuin deacetylase, regulates mitochondrial function and thermogenesis in brown adipocytes.
    The Journal of biological chemistry, Vol. 280, No. 14. (8 April 2005), pp. 13560-13567.
    by T Shi, F Wang, E Stieren, Q Tong
    posted to sirt3 by zhlei on 2008-04-25 00:01:19 as **
  • Mammalian SIRT1 limits replicative life span in response to chronic genotoxic stress
    Cell Metabolism, Vol. 2, No. 1. (July 2005), pp. 67-76.
    by Katrin F Chua, Raul Mostoslavsky, David B Lombard, Wendy W Pang, Shin'ichi Saito, Sonia Franco, Dhruv Kaushal, Hwei-Ling Cheng, Miriam R Fischer, Nicole Stokes, Michael M Murphy, Ettore Appella, Frederick W Alt
    posted to sirt1 senescence by zhlei on 2008-04-24 19:32:48 as **
  • Sirt1 inhibitor, Sirtinol, induces senescence-like growth arrest with attenuated Ras–MAPK signaling in human cancer cells
    Oncogene, Vol. aop, No. current.
    by H Ota, E Tokunaga, K Chang, M Hikasa, K Iijima, M Eto, K Kozaki, M Akishita, Y Ouchi, M Kaneki,
    posted to sirt1 by zhlei on 2008-04-24 18:33:40 as **
  • E2F1-Regulated MicroRNAs Impair TGF[beta]-Dependent Cell-Cycle Arrest and Apoptosis in Gastric Cancer
    Cancer Cell, Vol. 13, No. 3. (11 March 2008), pp. 272-286.
    by Fabio Petrocca, Rosa Visone, Mariadele R Onelli, Manisha H Shah, Milena S Nicoloso, Ivana de Martino, Dimitrios Iliopoulos, Emanuela Pilozzi, Chang-Gong Liu, Massimo Negrini, Luigi Cavazzini, Stefano Volinia, Hansjuerg Alder, Luigi P Ruco, Gustavo Baldassarre, Carlo M Croce, Andrea Vecchione
    posted to mirna by zhlei on 2008-04-21 15:13:41 as ** along with 1 person maralena
  • The SIRT1 deacetylase suppresses intestinal tumorigenesis and colon cancer growth.
    PLoS ONE, Vol. 3, No. 4. (2008)
    by R Firestein, G Blander, S Michan, P Oberdoerffer, S Ogino, J Campbell, A Bhimavarapu, S Luikenhuis, R de Cabo, C Fuchs, WC Hahn, LP Guarente, DA Sinclair
    posted to cancer sirt1 by zhlei on 2008-04-18 14:47:25 as ** along with 1 person jyuh
  • The deacetylase HDAC6 is a novel critical component of stress granules involved in the stress response
    Genes Dev., Vol. 21, No. 24. (15 December 2007), pp. 3381-3394.
    by Sohee Kwon, Yu Zhang, Patrick Matthias
    posted to dna-damage g3bp by zhlei on 2008-04-10 19:14:12 as ** along with 1 person kbjcflyer
  • Sirtuins in aging and age-related disease.
    Cell, Vol. 126, No. 2. (28 July 2006), pp. 257-268.
    by VD Longo, BK Kennedy
    posted to aging cancer sirt1 sirtuin by zhlei on 2008-04-08 22:24:32 as **
  • The p66shc adaptor protein controls oxidative stress response and life span in mammals.
    Nature, Vol. 402, No. 6759. (18 November 1999), pp. 309-313.
    by E Migliaccio, M Giorgio, S Mele, G Pelicci, P Reboldi, PP Pandolfi, L Lanfrancone, PG Pelicci
    posted to aging lifespan mitochondria p66shc ros by zhlei on 2008-04-04 21:15:48 as **
  • Sir2 and calorie restriction in yeast: A skeptical perspective
    Ageing Research Reviews, Vol. 6, No. 2. (August 2007), pp. 128-140.
    by Matt Kaeberlein, Powers
    posted to yeast sir2 cr calorie-restriction by zhlei on 2008-04-03 14:52:49 as **
  • SirT1 regulates energy metabolism and response to caloric restriction in mice.
    PLoS ONE, Vol. 3, No. 3. (2008)
    by G Boily, EL Seifert, L Bevilacqua, XH He, G Sabourin, C Estey, C Moffat, S Crawford, S Saliba, K Jardine, J Xuan, M Evans, ME Harper, MW McBurney
    posted to cr sirt1 by zhlei on 2008-04-03 14:39:36 as **
  • Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase.
    Science, Vol. 303, No. 5666. (26 March 2004), pp. 2011-2015.
    by A Brunet, LB Sweeney, JF Sturgill, KF Chua, PL Greer, Y Lin, H Tran, SE Ross, R Mostoslavsky, HY Cohen, LS Hu, HL Cheng, MP Jedrychowski, SP Gygi, DA Sinclair, FW Alt, ME Greenberg
    posted to foxo sirt1 sirtuin by zhlei on 2008-04-02 04:24:47 as ** along with 1 person jyuh
  • PHLPPing It off: Phosphatases Get in the Akt
    Molecular Cell, Vol. 25, No. 6. (23 March 2007), pp. 798-800.
    by Michelle C Mendoza, John Blenis
    posted to akt phlpp review by zhlei on 2008-04-01 15:34:17 as **
  • SIRT1 Regulates Apoptosis and Nanog Expression in Mouse Embryonic Stem Cells by Controlling p53 Subcellular Localization.
    Cell Stem Cell, Vol. 2, No. 3. (6 March 2008), pp. 241-251.
    by MK Han, EK Song, Y Guo, X Ou, C Mantel, HE Broxmeyer
    posted to sirt1 by zhlei on 2008-03-30 02:47:49 as **
  • SIRT1 Inhibition Alleviates Gene Silencing in Fragile X Mental Retardation Syndrome.
    PLoS Genet, Vol. 4, No. 3. (March 2008)
    by R Biacsi, D Kumari, K Usdin
    posted to sirt1 by zhlei on 2008-03-30 02:47:31 as **
  • Reactive species: A cell damaging rout assisting to chemical carcinogens.
    Cancer Lett (24 March 2008)
    by Mario E E Goetz, Andreas Luch
    posted to cancer ros by zhlei on 2008-03-28 20:18:08 as **
  • Signaling mechanisms involved in the response to genotoxic stress and regulating lifespan.
    Int J Biochem Cell Biol, Vol. 40, No. 2. (2008), pp. 176-180.
    by LJ Niedernhofer, PD Robbins
    posted to aging dna-damage review sirt1 by zhlei on 2008-03-28 20:12:20 as ** along with 1 person jyuh
  • Where in the cell is SIRT3?--functional localization of an NAD+-dependent protein deacetylase.
    Biochem J, Vol. 411, No. 2. (15 April 2008)
    by WC Hallows, BN Albaugh, JM Denu
    posted to sirt3 sirtuin by zhlei on 2008-03-28 20:10:41 as **
  • Mitochondria, oxidants, and aging.
    Cell, Vol. 120, No. 4. (25 February 2005), pp. 483-495.
    by RS Balaban, S Nemoto, T Finkel
    posted to aging cancer mitochondria review ros by zhlei on 2008-03-28 15:29:48 as **
  • Hop1 and the meiotic DNA-damage response.
    Cell, Vol. 132, No. 5. (7 March 2008), pp. 731-732.
    by N Hunter
    posted to dna-damage hop1 meiosis by zhlei on 2008-03-26 21:05:12 as **
  • Tat-SIRT1 Tango.
    Mol Cell, Vol. 29, No. 5. (14 March 2008), pp. 539-540.
    by Dalibor Blazek, B Matija M Peterlin
    posted to review sirt1 by zhlei on 2008-03-20 13:18:30 as **
  • Sirt1 contributes critically to the redox-dependent fate of neural progenitors.
    Nat Cell Biol (16 March 2008)
    by Timour Prozorovski, Ulf Schulze-Topphoff, Robert Glumm, Jan Baumgart, Friederike Schröter, Olaf Ninnemann, Elise Siegert, Ivo Bendix, Oliver Brüstle, Robert Nitsch, Frauke Zipp, Orhan Aktas
    posted to redox sirt1 sirtuin by zhlei on 2008-03-20 13:18:19 as ** along with 1 person epigenetics
  • SIRT1 Overexpression Antagonizes Cellular Senescence with Activated ERK/S6k1 Signaling in Human Diploid Fibroblasts.
    PLoS ONE, Vol. 3, No. 3. (2008)
    by J Huang, Q Gan, L Han, J Li, H Zhang, Y Sun, Z Zhang, T Tong
    posted to sirtuin by zhlei on 2008-03-06 21:35:35 as **
  • Berberine prevents UV-induced MMP-1 and reduction of type I procollagen expression in human dermal fibroblasts.
    Phytomedicine (26 December 2007)
    by Sangmin Kim, Jin Ho H Chung
    posted to aging by zhlei on 2008-02-20 02:47:50 as **
  • Hypoxia and metabolism: Hypoxia, DNA repair and genetic instability.
    Nat Rev Cancer (14 February 2008)
    by Robert G G Bristow, Richard P P Hill
    posted to dna-damage hypoxia review by zhlei on 2008-02-15 20:51:58 as ** along with 1 person jyuh
  • Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae.
    Nature, Vol. 423, No. 6936. (8 May 2003), pp. 181-185.
    by RM Anderson, KJ Bitterman, JG Wood, O Medvedik, DA Sinclair
    posted to lifespan sir2 sirt1 sirtuin by zhlei on 2008-02-14 03:48:23 as ** along with 2 people cito yedmonds
  • Calorie restriction promotes mitochondrial biogenesis by inducing the expression of eNOS.
    Science, Vol. 310, No. 5746. (14 October 2005), pp. 314-317.
    by E Nisoli, C Tonello, A Cardile, V Cozzi, R Bracale, L Tedesco, S Falcone, A Valerio, O Cantoni, E Clementi, S Moncada, MO Carruba
    posted to calorie_restriction cr enos mitochondria sirt1 by zhlei on 2008-02-12 19:13:46 as **
  • Coordination and communication between the p53 and IGF-1-AKT-TOR signal transduction pathways
    Genes Dev., Vol. 20, No. 3. (1 February 2006), pp. 267-275.
    by Arnold J Levine, Zhaohui Feng, Tak W Mak, Han You, Shengkan Jin
    posted to akt ifg1 p53 review tor by zhlei on 2008-01-09 15:24:35 as ** along with 1 person jyuh
  • SIRT1 sumoylation regulates its deacetylase activity and cellular response to genotoxic stress
    Nature Cell Biology, Vol. 9, No. 11. (14 October 2007), pp. 1253-1262.
    by Yonghua Yang, Wei Fu, Jiandong Chen, Nancy Olashaw, Xiaohong Zhang, Santo V Nicosia, Kapil Bhalla, Wenlong Bai
    posted to deacetylation dna-damage modification sirt1 sirtuin stress sumoylation by zhlei on 2008-01-06 19:43:22 as ** along with 1 person jyuh
  • Niacin restriction upregulates NADPH oxidase and reactive oxygen species (ROS) in human keratinocytes
    Free Radical Biology and Medicine, Vol. In Press, Corrected Proof
    by Claudia A Benavente, Elaine L Jacobson
    posted to ros by zhlei on 2008-01-06 19:42:29 as **
  • Early steps in the DNA base excision/single-strand interruption repair pathway in mammalian cells.
    Cell Res (1 January 2008)
    by Muralidhar L L Hegde, Tapas K K Hazra, Sankar Mitra
    posted to ber dna-damage repair review by zhlei on 2008-01-02 22:00:38 as **
  • Structure and mechanism for DNA lesion recognition.
    Cell Res (24 December 2007)
    by Wei Yang
    posted to dna-damage by zhlei on 2007-12-28 14:42:20 as **
  • A Functional Link Between SIRT1 Deacetylase and NBS1 in DNA Damage Response.
    Cell Cycle, Vol. 6, No. 23. (7 September 2007)
    by Zhigang Yuan, Edward Seto
    posted to deacetylation dna-damage sirt1 by zhlei on 2007-12-28 14:42:01 as **
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