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Hand preference and sex shape the architecture of language networks

by: Patric Hagmann, Leila Cammoun, Roberto Martuzzi, Philippe Maeder, Stephanie Clarke, Jean-Philippe Thiran, Reto Meuli
Human Brain Mapping, Vol. 27, No. 10. (2006), pp. 828-835.


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In right-handed subjects, language processing relies predominantly on left hemisphere networks, more so in men than in women, and in right- versus left-handers. Using DT-MRI tractography, we have shown that right-handed men are massively interconnected between the left-hemisphere language areas, whereas the homologous in the right hemisphere are sparse; interhemispheric connections between the language areas and their contralateral homologues are relatively strong. Women and left-handed men have equally strong intrahemispheric connections in both hemispheres, but women have a higher density of interhemispheric connections. Hum Brain Mapp, 2006. © 2006 Wiley-Liss, Inc.


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