Single-molecule Chemistry and Biology Special Feature: New directions in single-molecule imaging and analysis.

by: WE Moerner

Proc Natl Acad Sci U S A, Vol. 104, No. 31. (31 July 2007), pp. 12596-12602.

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Abstract

Optical imaging and analysis of single molecules continue to unfold as powerful ways to study the individual behavior of biological systems, unobscured by ensemble averaging. Current expansion of interest in this field is great, as evidenced by new meetings, journal special issues, and the large number of new investigators. Selected recent advances in biomolecular analysis are described, and two new research directions are summarized: superresolution imaging using single-molecule fluorescence and trapping of single molecules in solution by direct suppression of Brownian motion.

@article{citeulike:1604863, abstract = {Optical imaging and analysis of single molecules continue to unfold as powerful ways to study the individual behavior of biological systems, unobscured by ensemble averaging. Current expansion of interest in this field is great, as evidenced by new meetings, journal special issues, and the large number of new investigators. Selected recent advances in biomolecular analysis are described, and two new research directions are summarized: superresolution imaging using single-molecule fluorescence and trapping of single molecules in solution by direct suppression of Brownian motion.}, address = {Department of Chemistry, Stanford University, Stanford, CA 94305.}, author = {Moerner, W. E. }, citeulike-article-id = {1604863}, doi = {10.1073/pnas.0610081104}, issn = {0027-8424}, journal = {Proc Natl Acad Sci U S A}, keywords = {imaging, review, single\_molecule}, month = {July}, number = {31}, pages = {12596--12602}, posted-at = {2007-11-09 23:12:30}, priority = {3}, title = {Single-molecule Chemistry and Biology Special Feature: New directions in single-molecule imaging and analysis.}, url = {http://dx.doi.org/10.1073/pnas.0610081104}, volume = {104}, year = {2007} }

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TY - JOUR ID - citeulike:1604863 L3 - citeulike-article-id:1604863 TI - Single-molecule Chemistry and Biology Special Feature: New directions in single-molecule imaging and analysis. JF - Proc Natl Acad Sci U S A VL - 104 IS - 31 SP - 12596 EP - 12602 AD - Department of Chemistry, Stanford University, Stanford, CA 94305. SN - 0027-8424 N2 - Optical imaging and analysis of single molecules continue to unfold as powerful ways to study the individual behavior of biological systems, unobscured by ensemble averaging. Current expansion of interest in this field is great, as evidenced by new meetings, journal special issues, and the large number of new investigators. Selected recent advances in biomolecular analysis are described, and two new research directions are summarized: superresolution imaging using single-molecule fluorescence and trapping of single molecules in solution by direct suppression of Brownian motion. KW - imaging KW - review KW - single_molecule AU - Moerner, WE PY - 2007/07/31/ UR - http://dx.doi.org/10.1073/pnas.0610081104 ER -

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