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Discovering spatial working memory fields in prefrontal cortex

by: Xiao-Jing Wang
J Neurophysiol, Vol. 93, No. 6. (1 June 2005), pp. 3027-3028.


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This essay reviews the classic article by Funahashi, Bruce, and Goldman-Rakic on prefrontal cells for "memory field." The representaion of working memory in prefrontal cortex ever since has reached the cellular and microcircuitry level, according to Wang's comments. Previous studies have found activities in cortices other than prefrontal cortex (such as parietal cortex) during memory retention. Following the trend of studies in the field, the author vocalized the questions that are still under exploration: does the delay activity represent a sensory information, selection, or motor planning? Are there subdivisions in prefrontal cortex processing different types of information,such as object and spatial information?

wenhsin (public ) - 2006-03-15 21:26:30

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This essay looks at the historical significance of one APS classic paper that is freely available online: Funahashi S, Bruce CJ, and Goldman-Rakic PS. Mnemonic coding of visual space in the monkey's dorsolateral prefrontal cortex. J Neurophysiol 61: 331-349, 1989 (http://jn.physiology.org/cgi/reprint/61/2/331).


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