Perisomatic inhibition.

by: TF Freund, I Katona

Neuron, Vol. 56, No. 1. (4 October 2007), pp. 33-42.

View FullText article

DOI, Pubmed, Hubmed

Reviews [Write a review of this article]

There are no reviews of this article

Find related articles from these CiteULike users

balicea, agidon20, susannah

Find related articles with these CiteULike tags

balance, cerebral-cortex, clockwork, cog-neuro, cognitive-function, control, fine-tuning, inhibition, mood, mpl, network, neuro-chem, neuro-disorders, neuron, neuroplasticity, neuro-sync, neuro-timing, oscillation, pathology, perisomatic, reviews, rhythm

Abstract

Recent evidence supports the hypothesis of a functional dichotomy of perisomatic inhibition in the cerebral cortex: the parvalbumin- and cholecystokinin-containing basket cells that are specialized to control rhythm (as a clockwork) and "mood" (as a fine-tuning device), respectively, of network oscillations. Pathology extends this conclusion further, as the former is implicated in epilepsy and the latter in anxiety. The well-balanced cooperation of the two inhibitory systems is required for the normal network operations underlying the cognitive functions of the cerebral cortex.

@article{citeulike:2269822, abstract = {Recent evidence supports the hypothesis of a functional dichotomy of perisomatic inhibition in the cerebral cortex: the parvalbumin- and cholecystokinin-containing basket cells that are specialized to control rhythm (as a clockwork) and "mood" (as a fine-tuning device), respectively, of network oscillations. Pathology extends this conclusion further, as the former is implicated in epilepsy and the latter in anxiety. The well-balanced cooperation of the two inhibitory systems is required for the normal network operations underlying the cognitive functions of the cerebral cortex.}, address = {Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest, Hungary. Freund@koki.hu}, author = {Freund, T. F. and Katona, I. }, citeulike-article-id = {2269822}, doi = {http://dx.doi.org/10.1016/j.neuron.2007.09.012}, issn = {0896-6273}, journal = {Neuron}, keywords = {balance, cerebral-cortex, clockwork, cognitive-function, control, fine-tuning, inhibition, mood, network, neuron, oscillation, pathology, perisomatic, rhythm}, month = {October}, number = {1}, pages = {33--42}, posted-at = {2008-04-14 13:04:36}, priority = {2}, title = {Perisomatic inhibition.}, url = {http://dx.doi.org/10.1016/j.neuron.2007.09.012}, volume = {56}, year = {2007} }

RIS record

TY - JOUR ID - citeulike:2269822 L3 - citeulike-article-id:2269822 N2 - Recent evidence supports the hypothesis of a functional dichotomy of perisomatic inhibition in the cerebral cortex: the parvalbumin- and cholecystokinin-containing basket cells that are specialized to control rhythm (as a clockwork) and "mood" (as a fine-tuning device), respectively, of network oscillations. Pathology extends this conclusion further, as the former is implicated in epilepsy and the latter in anxiety. The well-balanced cooperation of the two inhibitory systems is required for the normal network operations underlying the cognitive functions of the cerebral cortex. IS - 1 JF - Neuron SN - 0896-6273 AD - Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest, Hungary. Freund@koki.hu EP - 42 TI - Perisomatic inhibition. VL - 56 SP - 33 KW - balance KW - cerebral-cortex KW - clockwork KW - cognitive-function KW - control KW - fine-tuning KW - inhibition KW - mood KW - network KW - neuron KW - oscillation KW - pathology KW - perisomatic KW - rhythm AU - Freund, TF AU - Katona, I PY - 2007/10/04/ UR - http://dx.doi.org/10.1016/j.neuron.2007.09.012 ER -

RIS BibTeX