Awareness of illness in schizophrenia and schizoaffective and mood disorders.

@article{citeulike:1891288, abstract = {BACKGROUND: The literature on insight, or self-awareness, in schizophrenia suggests that this cognitive dimension may be of nosological value. Poor insight has descriptive validity at the phenomenological and neuropsychological levels of schizophrenia and has prognostic validity in terms of the prediction of the course of illness. The lack of empirical data on the diagnostic specificity of poor insight to schizophrenia and the previous use of insight measures with questionable reliability and validity have limited this interpretation. METHODS: In the present study, we assessed insight into multiple aspects of mental disorder using a measure with demonstrated reliability and validity. A sample of 412 patients with psychotic and mood disorders coming from geographically diverse regions of the United States and one international site was studied. The main aims were to determine the prevalence of self-awareness deficits in patients in whom schizophrenia was diagnosed, to examine the relative severity of self-awareness deficits associated with schizophrenia compared with that of schizoaffective and mood disorders with and without psychosis, and to evaluate the clinical correlates of self-awareness in patients with schizophrenia. RESULTS: The results indicated that poor insight is a prevalent feature of schizophrenia. A variety of self-awareness deficits are more severe and pervasive in patients with schizophrenia than in patients with schizoaffective or major depressive disorders with or without psychosis and are associated with poorer psychosocial functioning. CONCLUSIONS: The results suggest that severe self-awareness deficits are a prevalent feature of schizophrenia, perhaps stemming from the neuropsychological dysfunction associated with the disorder, and are more common in schizophrenia than in other psychotic disorders.}, address = {Department of Clinical Psychobiology, New York State Psychiatric Institute.}, author = {Amador, X. F. and Flaum, M. and Andreasen, N. C. and Strauss, D. H. and Yale, S. A. and Clark, S. C. and Gorman, J. M. }, citeulike-article-id = {1891288}, issn = {0003-990X}, journal = {Arch Gen Psychiatry}, keywords = {mood, neuropsychology}, month = {October}, number = {10}, pages = {826--836}, posted-at = {2007-12-17 14:57:14}, priority = {2}, title = {Awareness of illness in schizophrenia and schizoaffective and mood disorders.}, url = {http://view.ncbi.nlm.nih.gov/pubmed/7944872}, volume = {51}, year = {1994} }

TY - JOUR ID - citeulike:1891288 L3 - citeulike-article-id:1891288 TI - Awareness of illness in schizophrenia and schizoaffective and mood disorders. JF - Arch Gen Psychiatry VL - 51 IS - 10 SP - 826 EP - 836 AD - Department of Clinical Psychobiology, New York State Psychiatric Institute. SN - 0003-990X N2 - BACKGROUND: The literature on insight, or self-awareness, in schizophrenia suggests that this cognitive dimension may be of nosological value. Poor insight has descriptive validity at the phenomenological and neuropsychological levels of schizophrenia and has prognostic validity in terms of the prediction of the course of illness. The lack of empirical data on the diagnostic specificity of poor insight to schizophrenia and the previous use of insight measures with questionable reliability and validity have limited this interpretation. METHODS: In the present study, we assessed insight into multiple aspects of mental disorder using a measure with demonstrated reliability and validity. A sample of 412 patients with psychotic and mood disorders coming from geographically diverse regions of the United States and one international site was studied. The main aims were to determine the prevalence of self-awareness deficits in patients in whom schizophrenia was diagnosed, to examine the relative severity of self-awareness deficits associated with schizophrenia compared with that of schizoaffective and mood disorders with and without psychosis, and to evaluate the clinical correlates of self-awareness in patients with schizophrenia. RESULTS: The results indicated that poor insight is a prevalent feature of schizophrenia. A variety of self-awareness deficits are more severe and pervasive in patients with schizophrenia than in patients with schizoaffective or major depressive disorders with or without psychosis and are associated with poorer psychosocial functioning. CONCLUSIONS: The results suggest that severe self-awareness deficits are a prevalent feature of schizophrenia, perhaps stemming from the neuropsychological dysfunction associated with the disorder, and are more common in schizophrenia than in other psychotic disorders. KW - mood KW - neuropsychology AU - Amador, XF AU - Flaum, M AU - Andreasen, NC AU - Strauss, DH AU - Yale, SA AU - Clark, SC AU - Gorman, JM PY - 1994/10// UR - http://view.ncbi.nlm.nih.gov/pubmed/7944872 ER -