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sobolevnrms drug_design [92 articles]

Neue Publikationen in sobolevnrms Bibliothek eingetragen unter dem Bezeichner: drug_design. You can also see everyone's drug_design.
  • Synthesis and bioassay of improved mosquito repellents predicted from chemical structure
    Proceedings of the National Academy of Sciences, Vol. 105, No. 21. (2008), pp. 7359-7364.
    by Alan R Katritzky, Zuoquan Wang, Svetoslav Slavov, Maia Tsikolia, Dimitar Dobchev, Novruz G Akhmedov, Dennis C Hall, Ulrich R Bernier, Gary G Clark, Kenneth J Linthicum
    posted to drug_design by sobolevnrm on 2008-07-25 11:47:14 as read
  • Absorption Classification of Oral Drugs Based on Molecular Surface Properties
    J. Med. Chem., Vol. 46, No. 4. (13 February 2003), pp. 558-570.
  • Ensemble-Based Virtual Screening Reveals Potential Novel Antiviral Compounds for Avian Influenza Neuraminidase
    J. Med. Chem. (18 June 2008)
    by Lily S Cheng, Rommie E Amaro, Dong Xu, Wilfred W Li, Peter W Arzberger, Andrew J Mccammon
  • Release of hydrophobic molecules from polymer micelles into cell membranes revealed by Forster resonance energy transfer imaging
    Proceedings of the National Academy of Sciences, Vol. 105, No. 18. (6 May 2008), pp. 6596-6601.
    by Hongtao Chen, Sungwon Kim, Li Li, Shuyi Wang, Kinam Park, Ji-Xin Cheng
  • Targeted Quantum Dot Conjugates for siRNA Delivery.
    Bioconjug Chem (14 July 2007)
    by Austin M Derfus, Alice A Chen, Dal-Hee H Min, Erkki Ruoslahti, Sangeeta N Bhatia
  • Quantum dots to monitor RNAi delivery and improve gene silencing
    Nucleic Acids Research, Vol. 33, No. 22. (2005), pp. e190-e190.
    by Alice A Chen, Austin M Derfus, Salman R Khetani, Sangeeta N Bhatia
  • Imaging in the era of molecular oncology
    Nature, Vol. 452, No. 7187. (3 April 2008), pp. 580-589.
    by Ralph Weissleder, Mikael J Pittet
  • Minute dosages of alphanubeta3-targeted fumagillin nanoparticles impair Vx-2 tumor angiogenesis and development in rabbits
    FASEB J. (24 March 2008), fj.07-103929.
    by Patrick M Winter, Anne H Schmieder, Shelton D Caruthers, Jeffery L Keene, Huiying Zhang, Samuel A Wickline, Gregory M Lanza
  • New mechanisms for non-porative ultrasound stimulation of cargo delivery to cell cytosol with targeted perfluorocarbon nanoparticles
    Nanotechnology, Vol. 19, No. 18. (2008), 185102.
    by NR Soman, JN Marsh, GM Lanza, SA Wickline
  • From the Cover: Precise engineering of targeted nanoparticles by using self-assembled biointegrated block copolymers
    Proceedings of the National Academy of Sciences, Vol. 105, No. 7. (19 February 2008), pp. 2586-2591.
    by Frank Gu, Liangfang Zhang, Benjamin A Teply, Nina Mann, Andrew Wang, Aleksandar F Radovic-Moreno, Robert Langer, Omid C Farokhzad
  • Nanoparticulate delivery of suicide DNA to murine prostate and prostate tumors
    The Prostate, Vol. 67, No. 8. (2007), pp. 855-862.
    by Weidan Peng, Daniel G Anderson, Yunhua Bao, Robert F Padera, Robert Langer, Janet A Sawicki
  • Nanoparticle Imaging of Integrins on Tumor Cells
    Neoplasia, Vol. 8, No. 3. (March 2006), pp. 214-222.
    by Xavier Montet, Karin Montet-Abou, Fred Reynolds, Ralph Weissleder, Lee Josephson
  • A Macrophage-Targeted Theranostic Nanoparticle for Biomedical Applications
    Small, Vol. 2, No. 8-9. (2006), pp. 983-987.
  • Polymeric Nanoparticle Preparation that Eradicates Tumors
    Nano Lett., Vol. 5, No. 12. (14 December 2005), pp. 2552-2556.
  • Multivalent Effects of RGD Peptides Obtained by Nanoparticle Display
    J. Med. Chem., Vol. 49, No. 20. (5 October 2006), pp. 6087-6093.
  • Enhancement of a human immunodeficiency virus env DNA vaccine using a novel polycationic nanoparticle formulation
    Immunology Letters, Vol. 90, No. 2-3. (15 December 2003), pp. 67-70.
    by Christopher P Locher, David Putnam, Robert Langer, Stephanie A Witt, Brittany M Ashlock, Jay A Levy
  • Biodegradable polymeric microspheres and nanospheres for drug delivery in the peritoneum
    Journal of Biomedical Materials Research Part A, Vol. 77A, No. 2. (2006), pp. 351-361.
    by Daniel S Kohane, Julie Y Tse, Yoon Yeo, Robert Padera, Maria Shubina, Robert Langer
  • Electrostatic Ligand Coatings of Nanoparticles Enable Ligand-Specific Gene Delivery to Human Primary Cells
    Nano Lett., Vol. 7, No. 4. (11 April 2007), pp. 874-879.
    by JJ Green, E Chiu, ES Leshchiner, J Shi, R Langer, DG Anderson
  • Noncavitational mechanisms of interaction of ultrasound with targeted perfluorocarbon nanoparticles: implications for drug delivery
    Ultrasonics Symposium, 2005 IEEE, Vol. 3 (2005), pp. 1712-1715.
    by NR Soman, JN Marsh, MS Hughes, GM Lanza, SA Wickline
  • P2G-1 Ultrasound Enhances Cellular Lipid Trafficking: Implications for Lipid Therapy
    Ultrasonics Symposium, 2006. IEEE (2006), pp. 1730-1733.
    by NR Soman, JN Marsh, MS Hughes, GM Lanza, SA Wickline
  • Quantum Dot-Aptamer Conjugates for Synchronous Cancer Imaging, Therapy, and Sensing of Drug Delivery Based on Bi-Fluorescence Resonance Energy Transfer
    Nano Lett. (14 September 2007)
  • First experience with noncavitational ultrasound enhancement of selective cellular delivery of liquid perfluorocarbon nanoparticles to Angiogenic sites
    Journal of the American College of Cardiology, Vol. 41, No. 6, Supplement 1. (19 March 2003), 59.
    by Kathryn C Crowder, Michael S Hughes, Jon N Marsh, Michael J Scott, Lori Chinen, Thomas D Harris, Gregory M Lanza, Samuel A Wickline
  • Augmented and selective delivery of liquid perfluorocarbon nanoparticles to melanoma cells with noncavitational ultrasound
    Ultrasonics, 2003 IEEE Symposium on, Vol. 1 (2003), pp. 532-535 Vol.1.
    by KC Crowder, MS Hughes, JN Marsh, MJ Scott, RW Fuhrhop, GM Lanza, SA Wickline
  • Formulation of functionalized PLGA-PEG nanoparticles for in vivo targeted drug delivery
    Biomaterials, Vol. 28, No. 5. (February 2007), pp. 869-876.
    by Jianjun Cheng, Benjamin A Teply, Ines Sherifi, Josephine Sung, Gaurav Luther, Frank X Gu, Etgar Levy-Nissenbaum, Aleksandar F Radovic-Moreno, Robert Langer, Omid C Farokhzad
  • Multi-reservoir device for detecting a soluble cancer biomarker
    Lab Chip, Vol. 7 (2007), pp. 288-1293.
    by Karen D Daniel, Grace Y Kim, Christophoros C Vassiliou, Farzad Jalali-Yazdi, Robert Langer, Michael J Cima
    posted to cancer ccne drug_design nanotech by sobolevnrm on 2008-02-22 11:56:18 as read along with 1 person ml115
  • Poly(ethylene oxide)-Modified Poly(β-amino ester) Nanoparticles as a pH-Sensitive System for Tumor-Targeted Delivery of Hydrophobic Drugs. 1. In Vitro Evaluations
    Mol. Pharmaceutics, Vol. 2, No. 5. (3 October 2005), pp. 357-366.
    by D Shenoy, S Little, R Langer, M Amiji
  • Poly(Ethylene Oxide)-Modified Poly(β-Amino Ester) Nanoparticles as a pH-Sensitive System for Tumor-Targeted Delivery of Hydrophobic Drugs: Part 2. In Vivo Distribution and Tumor Localization Studies
    Pharmaceutical Research, Vol. 22, No. 12. (20 December 2005), pp. 2107-2114.
    by Dinesh Shenoy, Steven Little, Robert Langer, Mansoor Amiji
  • Poly(ethylene oxide)-modified poly(beta-amino ester) nanoparticles as a pH-sensitive system for tumor-targeted delivery of hydrophobic drugs: part 3. Therapeutic efficacy and safety studies in ovarian cancer xenograft model
    Cancer Chemotherapy and Pharmacology, Vol. 59, No. 4. (March 2007), pp. 477-484.
  • Targeted nanoparticle-aptamer bioconjugates for cancer chemotherapy in vivo
    PNAS, Vol. 103, No. 16. (18 April 2006), pp. 6315-6320.
    by Omid C Farokhzad, Jianjun Cheng, Benjamin A Teply, Ines Sherifi, Sangyong Jon, Philip W Kantoff, Jerome P Richie, Robert Langer
  • Imaging of Vx-2 rabbit tumors with alpha(nu)beta3-integrin-targeted 111In nanoparticles.
    Int J Cancer, Vol. 120, No. 9. (1 May 2007), pp. 1951-1957.
    by G Hu, M Lijowski, H Zhang, KC Partlow, SD Caruthers, G Kiefer, G Gulyas, P Athey, MJ Scott, SA Wickline, GM Lanza
  • Studies on Anticancer Activities of Antimicrobial Peptides
    Biochimica et Biophysica Acta (BBA) - Biomembranes, Vol. In Press, Accepted Manuscript
    by David W Hoskin, Ayyalusamy Ramamoorthy
  • Flexible ligand-flexible protein docking in protein kinase systems
    Biochimica et Biophysica Acta (BBA) - Proteins & Proteomics, Vol. 1784, No. 1. (January 2008), pp. 244-251.
    by Chung F Wong
  • Model of Drug-Loaded Fluorocarbon-Based Micelles Studied by Electron-Spin Induced 19F Relaxation NMR and Molecular Dynamics Simulation
    Langmuir (1 December 2007)
    by EV Mathias, X Liu, O Franco, I Khan, Y Ba, JA Kornfield
    posted to drug_design nanotech by sobolevnrm on 2008-01-07 12:45:30 as read along with 1 group baker-group
  • DrugBank: a knowledgebase for drugs, drug actions and drug targets
    Nucl. Acids Res. (11 December 2007), gkm958.
    by David S Wishart, Craig Knox, An C Guo, Dean Cheng, Savita Shrivastava, Dan Tzur, Bijaya Gautam, Murtaza Hassanali
  • Specificity in Molecular Design: A Physical Framework for Probing the Determinants of Binding Specificity and Promiscuity in a Biological Environment
    J. Phys. Chem. B, Vol. 111, No. 47. (29 November 2007), pp. 13419-13435.
  • Modeling the Thermodynamics of the Interaction of Nanoparticles with Cell Membranes
    Nano Lett., Vol. 7, No. 12. (12 December 2007), pp. 3716-3722.
  • An atomistic model of passive membrane permeability: application to a series of FDA approved drugs
    Journal of Computer-Aided Molecular Design
    by Chakrapani Kalyanaraman, Matthew Jacobson
  • Molecular Recognition by Cholesterol Esterase of Active Site Ligands: Structure-Reactivity Effects for Inhibition by Aryl Carbamates and Subsequent Carbamylenzyme Turnover
    Biochemistry, Vol. 35, No. 51. (24 December 1996), pp. 16723-16734.
    by SR Feaster, K Lee, N Baker, DY Hui, DM Quinn
    posted to drug_design kinetics oxysterols by sobolevnrm on 2007-10-16 12:36:38 as read along with 1 group baker-group
  • New and Original pKa Prediction Method Using Grid Molecular Interaction Fields
    J. Chem. Inf. Model. (2 October 2007)
  • Fluorine in Pharmaceuticals: Looking Beyond Intuition
    Science, Vol. 317, No. 5846. (28 September 2007), pp. 1881-1886.
    by Klaus Muller, Christoph Faeh, Francois Diederich
    posted to drug_design misc by sobolevnrm on 2007-10-03 12:31:36 as read along with 1 group baker-group
  • Nanotechnology Applications in Cancer
    Annual Review of Biomedical Engineering, Vol. 9 (2007), pp. 257-88.
    by S Nie, Y Xing, GJ Kim, JW Simons
    posted to drug_design nanotech by sobolevnrm on 2007-07-26 13:34:06 as read along with 1 group baker-group
  • MR Three-Dimensional Molecular Imaging of Intramural Biomarkers with Targeted Nanoparticles
    Journal of Cardiovascular Magnetic Resonance, Vol. 8, No. 3. (2006), pp. 535-41.
    posted to drug_design nanotech by sobolevnrm on 2007-05-25 14:38:05 as read along with 1 group baker-group
  • Biodistribution and anti-tumor efficacy of doxorubicin loaded glycol-chitosan nanoaggregates by EPR effect
    Journal of Controlled Release, Vol. 91, No. 1-2. (2003), pp. 135-45.
    by YJ Son, JS Jang, YW Cho, H Chung, RW Park, IC Kwon, IS Kim, JY Park, SB Seo, CR Park, SY Jeong
    posted to drug_design nanotech by sobolevnrm on 2007-05-25 14:38:05 as read along with 1 group baker-group
  • Nanotechnological applications in medicine
    Current Opinion in Biotechnology, Vol. 18, No. 1. (2007), pp. 26-30.
    by SD Caruthers, SA Wickline, GM Lanza
    posted to drug_design nanotech by sobolevnrm on 2007-05-25 14:38:05 as read along with 1 group baker-group
  • Shape effects of filaments versus spherical particles in flow and drug delivery
    Nature Nanotechnology, Vol. 2, No. 4. (2007), pp. 249-55.
    by Y Geng, P Dalhaimer, S Cai, R Tsai, M Tewari, T Minko, DE Discher
    posted to drug_design nanotech by sobolevnrm on 2007-05-25 14:37:07 as read along with 1 group baker-group
  • Emerging nanomedicine opportunities with perfluorocarbon nanoparticles
    Expert Review of Medical Devices, Vol. 4, No. 2. (2007), pp. 137-45.
    by PM Winter, K Cai, SD Caruthers, SA Wickline, GM Lanza
    posted to drug_design emulsions nanotech by sobolevnrm on 2007-05-25 14:37:06 as read along with 1 group baker-group
  • Controlling Liposomal Drug Release with Low Frequency Ultrasound: Mechanism and Feasibility
    Langmuir (in press)
  • Biomimetic amplification of nanoparticle homing to tumors
    Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, No. 3. (2007), pp. 932-6.
    by D Simberg, T Duza, JH Park, M Essler, J Pilch, L Zhang, AM Derfus, M Yang, RM Hoffman, S Bhatia, MJ Sailor, E Ruoslahti
    posted to drug_design nanotech by sobolevnrm on 2007-05-25 14:36:05 as read along with 1 group baker-group
  • Preparation of Organic Nanoparticles Using Microemulsions: Their Potential Use in Transdermal Delivery
    Langmuir (in press)
    by C Destrée, J Ghijsen, JB Nagy
    posted to drug_design emulsions nanotech by sobolevnrm on 2007-05-25 14:36:04 as read along with 1 group baker-group
  • Nanoparticle-Mediated Drug Delivery and Gene Therapy
    Biotechnology Progress (in press)
    by S Jin, K Ye
    posted to drug_design nanotech by sobolevnrm on 2007-05-25 14:36:04 as read along with 1 group baker-group
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