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DAnTE: a statistical tool for quantitative analysis of -omics databy: Ashoka D Polpitiya, Wei-Jun Qian, Navdeep Jaitly, Vladislav A Petyuk, Joshua N Adkins, David G Camp, Gordon A Anderson, Richard D Smith
Bioinformatics (3 May 2008), btn217.
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AbstractSummary: DAnTE (Data Analysis Tool Extension) is a statistical tool designed to address challenges associated with quantitative bottom-up, shotgun proteomics data. This tool has also been demonstrated for microarray data and can easily be extended to other high-throughput data types. DAnTE features selected normalization methods, missing value imputation algorithms, peptide to protein rollup methods, an extensive array of plotting functions, and a comprehensive hypothesis testing scheme that can handle unbalanced data and random effects. The Graphical User Interface (GUI) is designed to be very intuitive and user friendly. Availability: DAnTE may be downloaded free of charge at http://ncrr.pnl.gov/software/ Contact: rds@pnl.gov or proteomics@pnl.gov Supplementary information: An example dataset with instructions on how to perform a series of analysis steps is available at http://ncrr.pnl.gov/software/ 10.1093/bioinformatics/btn217
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