Genome-Scale Proteomics Reveals Arabidopsis thaliana Gene Models and Proteome Dynamics

@article{citeulike:2724238, abstract = {We have assembled a proteome map for Arabidopsis thaliana from high-density, organ-specific proteome catalogs that we generated for different organs, developmental stages, and undifferentiated cultured cells. We matched 86,456 unique peptides to 13,029 proteins and provide expression evidence for 57 gene models that are not represented in the TAIR7 protein database. Analysis of the proteome identified organ-specific biomarkers and allowed us to compile an organ-specific set of proteotypic peptides for 4105 proteins to facilitate targeted quantitative proteomics surveys. Quantitative information for the identified proteins was used to establish correlations between transcript and protein accumulation in different plant organs. The Arabidopsis proteome map provides information about genome activity and proteome assembly and is available as a resource for plant systems biology. 10.1126/science.1157956}, author = {Baerenfaller, Katja and Grossmann, Jonas and Grobei, Monica A. and Hull, Roger and Hirsch-Hoffmann, Matthias and Yalovsky, Shaul and Zimmermann, Philip and Grossniklaus, Ueli and Gruissem, Wilhelm and Baginsky, Sacha }, citeulike-article-id = {2724238}, doi = {10.1126/science.1157956}, journal = {Science}, keywords = {proteome}, month = {April}, pages = {1157956+}, posted-at = {2008-05-16 21:32:53}, priority = {2}, title = {Genome-Scale Proteomics Reveals Arabidopsis thaliana Gene Models and Proteome Dynamics}, url = {http://dx.doi.org/10.1126/science.1157956}, year = {2008} }

TY - JOUR ID - citeulike:2724238 L3 - citeulike-article-id:2724238 TI - Genome-Scale Proteomics Reveals Arabidopsis thaliana Gene Models and Proteome Dynamics JF - Science SP - 1157956 N2 - We have assembled a proteome map for Arabidopsis thaliana from high-density, organ-specific proteome catalogs that we generated for different organs, developmental stages, and undifferentiated cultured cells. We matched 86,456 unique peptides to 13,029 proteins and provide expression evidence for 57 gene models that are not represented in the TAIR7 protein database. Analysis of the proteome identified organ-specific biomarkers and allowed us to compile an organ-specific set of proteotypic peptides for 4105 proteins to facilitate targeted quantitative proteomics surveys. Quantitative information for the identified proteins was used to establish correlations between transcript and protein accumulation in different plant organs. The Arabidopsis proteome map provides information about genome activity and proteome assembly and is available as a resource for plant systems biology. 10.1126/science.1157956 KW - proteome AU - Baerenfaller, Katja AU - Grossmann, Jonas AU - Grobei, Monica AU - Hull, Roger AU - Hirsch-Hoffmann, Matthias AU - Yalovsky, Shaul AU - Zimmermann, Philip AU - Grossniklaus, Ueli AU - Gruissem, Wilhelm AU - Baginsky, Sacha PY - 2008/04/24/ UR - http://dx.doi.org/10.1126/science.1157956 ER -