Stretching of macromolecules and proteins

@article{citeulike:1946368, abstract = {In this paper we review the biophysics revealed by stretching single biopolymers. During the last decade various techniques have emerged allowing micromanipulation of single molecules and simultaneous measurements of their elasticity. Using such techniques, it has been possible to investigate some of the interactions playing a role in biology. We shall first review the simplest case of a non-interacting polymer and then present the structural transitions in DNA, RNA and proteins that have been studied by single-molecule techniques. We shall explain how these techniques permit a new approach to the protein folding/unfolding transition.}, author = {Strick, T. R. }, citeulike-article-id = {1946368}, keywords = {dna, wlc}, posted-at = {2007-11-20 19:01:54}, priority = {2}, title = {Stretching of macromolecules and proteins}, url = {http://www.ingentaconnect.com/content/iop/ropp/2003/00000066/00000001/art00201}, year = {2003} }

TY - JOUR ID - citeulike:1946368 L3 - citeulike-article-id:1946368 TI - Stretching of macromolecules and proteins N2 - In this paper we review the biophysics revealed by stretching single biopolymers. During the last decade various techniques have emerged allowing micromanipulation of single molecules and simultaneous measurements of their elasticity. Using such techniques, it has been possible to investigate some of the interactions playing a role in biology. We shall first review the simplest case of a non-interacting polymer and then present the structural transitions in DNA, RNA and proteins that have been studied by single-molecule techniques. We shall explain how these techniques permit a new approach to the protein folding/unfolding transition. KW - dna KW - wlc AU - Strick, TR PY - 2003/// UR - http://www.ingentaconnect.com/content/iop/ropp/2003/00000066/00000001/art00201 ER -