How Athila retrotransposons survive in the Arabidopsis genome

@article{citeulike:2800447, abstract = {BACKGROUND:Transposable elements are selfish genetic sequences which only occasionally provide useful functions to their host species. In addition, models of mobile element evolution assume a second type of selfishness: elements of different familes do not cooperate, but they independently fight for their survival in the host genome.RESULTS:We show that recombination events among distantly related Athila retrotransposons have led to the generation of new Athila lineages. Their pattern of diversification suggests that Athila elements survive in Arabidopsis by a combination of selfish replication and of amplification of highly diverged copies with coding potential. Many Athila elements are non-autonomous but still conserve intact open reading frames which are under the effect of negative, purifying natural selection. CONCLUSIONS:The evolution of these mobile elements is far more complex than hitherto assumed. Strict selfish replication does not explain all the patterns observed.}, author = {Marco, Antonio and Marin, Ignacio }, citeulike-article-id = {2800447}, doi = {10.1186/1471-2164-9-219}, journal = {BMC Genomics}, keywords = {arabidopsis, genomics\_analysis}, number = {1}, posted-at = {2008-05-15 02:19:15}, priority = {2}, title = {How Athila retrotransposons survive in the Arabidopsis genome}, url = {http://dx.doi.org/10.1186/1471-2164-9-219}, volume = {9}, year = {2008} }

TY - JOUR ID - citeulike:2800447 L3 - citeulike-article-id:2800447 TI - How Athila retrotransposons survive in the Arabidopsis genome JF - BMC Genomics VL - 9 IS - 1 N2 - BACKGROUND:Transposable elements are selfish genetic sequences which only occasionally provide useful functions to their host species. In addition, models of mobile element evolution assume a second type of selfishness: elements of different familes do not cooperate, but they independently fight for their survival in the host genome.RESULTS:We show that recombination events among distantly related Athila retrotransposons have led to the generation of new Athila lineages. Their pattern of diversification suggests that Athila elements survive in Arabidopsis by a combination of selfish replication and of amplification of highly diverged copies with coding potential. Many Athila elements are non-autonomous but still conserve intact open reading frames which are under the effect of negative, purifying natural selection. CONCLUSIONS:The evolution of these mobile elements is far more complex than hitherto assumed. Strict selfish replication does not explain all the patterns observed. KW - arabidopsis KW - genomics_analysis AU - Marco, Antonio AU - Marin, Ignacio PY - 2008/// UR - http://dx.doi.org/10.1186/1471-2164-9-219 ER -