Proteinuria as a significant determinant of hypertension in a normotensive screened cohort in Okinawa, Japan.

@article{citeulike:3359435, abstract = {To evaluate the influence of proteinuria on the development of hypertension in normotensive screened subjects. We studied 4,428 normotensive subjects without heart disease (2888 men, 1540 women, age 19-89 years) who were participants in a 1-day health evaluation in both 1997 and 2000. The 3-year frequency of developing hypertension was 6.0\% in subjects without proteinuria, and 13.5\% in subjects with proteinuria. The odds ratio for developing hypertension by age (year) increased approximately 1.6\%. Obesity was associated with an approximately 40\% increased risk of hypertension; proteinuria increased the risk of hypertension 2-fold. Proteinuria was a significant predictor of developing hypertension. Age, obesity, and initial blood pressure level also contributed to the development of hypertension. In conclusion, proteinuria is a powerful predictor of developing hypertension. Age and obesity are also associated with increased risk of hypertension. Lifestyle modification might thus be necessary, particularly in subjects with proteinuria.}, author = {Inoue, T. and Iseki, K. and Higashiuesato, Y. and Nagahama, K. and Matsuoka, M. and Iseki, C. and Ohya, Y. and Kinjo, K. and Takishita, S. }, citeulike-article-id = {3359435}, issn = {0916-9636}, journal = {Hypertension research : official journal of the Japanese Society of Hypertension}, keywords = {bp, japan, proteinuria}, month = {September}, number = {9}, pages = {687--693}, posted-at = {2008-09-30 16:30:32}, priority = {2}, title = {Proteinuria as a significant determinant of hypertension in a normotensive screened cohort in Okinawa, Japan.}, url = {http://view.ncbi.nlm.nih.gov/pubmed/17249524}, volume = {29}, year = {2006} }

TY - JOUR ID - citeulike:3359435 L3 - citeulike-article-id:3359435 N2 - To evaluate the influence of proteinuria on the development of hypertension in normotensive screened subjects. We studied 4,428 normotensive subjects without heart disease (2888 men, 1540 women, age 19-89 years) who were participants in a 1-day health evaluation in both 1997 and 2000. The 3-year frequency of developing hypertension was 6.0% in subjects without proteinuria, and 13.5% in subjects with proteinuria. The odds ratio for developing hypertension by age (year) increased approximately 1.6%. Obesity was associated with an approximately 40% increased risk of hypertension; proteinuria increased the risk of hypertension 2-fold. Proteinuria was a significant predictor of developing hypertension. Age, obesity, and initial blood pressure level also contributed to the development of hypertension. In conclusion, proteinuria is a powerful predictor of developing hypertension. Age and obesity are also associated with increased risk of hypertension. Lifestyle modification might thus be necessary, particularly in subjects with proteinuria. IS - 9 JF - Hypertension research : official journal of the Japanese Society of Hypertension SN - 0916-9636 EP - 693 TI - Proteinuria as a significant determinant of hypertension in a normotensive screened cohort in Okinawa, Japan. VL - 29 SP - 687 KW - bp KW - japan KW - proteinuria AU - Inoue, T AU - Iseki, K AU - Higashiuesato, Y AU - Nagahama, K AU - Matsuoka, M AU - Iseki, C AU - Ohya, Y AU - Kinjo, K AU - Takishita, S PY - 2006/09// UR - http://view.ncbi.nlm.nih.gov/pubmed/17249524 ER -