Networking pathways unveils association between obesity and non-insulin dependent diabetes mellitus.

@article{citeulike:3135105, abstract = {Genetic related health problems are often interrelated. Current practices to establish associations between diseases are expensive and rarely can reflect underlying molecular mechanisms, We propose a general framework to associate diseases by networking pathways. By applying our method on association study of non-insulin dependent diabetes mellitus (NIDDM) and obesity, we demonstrate that our method can both identify signature pathways for each disease and establish valid association of two diseases.}, address = {School of lnformatics and Center for Computational Biology and Bioinformatics, Indiana University, 410 West 10th street, Suite 5000, Indianapolis, IN 46202, USA.}, author = {Hu, H. and Li, X. }, citeulike-article-id = {3135105}, issn = {1793-5091}, journal = {Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing}, keywords = {dm, genetics, obesity, pathway, text-mining}, pages = {255--266}, posted-at = {2008-08-19 04:28:22}, priority = {2}, title = {Networking pathways unveils association between obesity and non-insulin dependent diabetes mellitus.}, url = {http://view.ncbi.nlm.nih.gov/pubmed/18229691}, year = {2008} }

TY - JOUR ID - citeulike:3135105 L3 - citeulike-article-id:3135105 N2 - Genetic related health problems are often interrelated. Current practices to establish associations between diseases are expensive and rarely can reflect underlying molecular mechanisms, We propose a general framework to associate diseases by networking pathways. By applying our method on association study of non-insulin dependent diabetes mellitus (NIDDM) and obesity, we demonstrate that our method can both identify signature pathways for each disease and establish valid association of two diseases. JF - Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing SN - 1793-5091 AD - School of lnformatics and Center for Computational Biology and Bioinformatics, Indiana University, 410 West 10th street, Suite 5000, Indianapolis, IN 46202, USA. EP - 266 TI - Networking pathways unveils association between obesity and non-insulin dependent diabetes mellitus. SP - 255 KW - dm KW - genetics KW - obesity KW - pathway KW - text-mining AU - Hu, H AU - Li, X PY - 2008/// UR - http://view.ncbi.nlm.nih.gov/pubmed/18229691 ER -