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Microarray-based expression profiling and informatics

by: Richard Simon
Current Opinion in Biotechnology, Vol. 19, No. 1. (February 2008), pp. 26-29.


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Microarray-based expression profiling is a powerful technology for studying biological mechanisms and for developing clinically valuable predictive classifiers. The high-dimensional read-out for each sample assayed makes it possible to do new kinds of studies but also increases the risks of misleading conclusions. We review here the current state-of-the-art for design and analysis of microarray-based investigations.


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