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happy_manatees abcb1 [23 articles]

Neue Publikationen in happy_manatees Bibliothek eingetragen unter dem Bezeichner: abcb1. You can also see everyone's abcb1.
  • Insertion of an arginine residue into the transmembrane segments corrects protein misfolding.
    J Biol Chem, Vol. 281, No. 40. (6 October 2006), pp. 29436-29440.
    by TW Loo, MC Bartlett, DM Clarke
    posted to processing folding abcb1 by happy_manatee on 2007-01-17 17:40:18 as ** along with 1 person softsimu
  • The multidrug transporter, P-glycoprotein, actively mediates cholesterol redistribution in the cell membrane
    PNAS, Vol. 99, No. 16. (6 August 2002), pp. 10347-10352.
    by Alexia Garrigues, Alexandre E Escargueil, Stephane Orlowski
    posted to abcb1 mutants pgp pgpmuts by happy_manatee on 2006-11-28 20:06:42 as **
  • Location of the rhodamine-binding site in the human multidrug resistance P-glycoprotein.
    J Biol Chem, Vol. 277, No. 46. (15 November 2002), pp. 44332-44338.
    by TW Loo, DM Clarke
    posted to abcb1 mutants pgp pgpmuts by happy_manatee on 2006-11-28 20:02:58 as **
  • The dileucine motif at the COOH terminus of human multidrug resistance P-glycoprotein is important for folding but not activity.
    J Biol Chem, Vol. 280, No. 4. (28 January 2005), pp. 2522-2528.
    by TW Loo, MC Bartlett, DM Clarke
    posted to abcb1 mutants pgp pgpmuts by happy_manatee on 2006-11-28 19:59:44 as **
  • The conserved tyrosine residues 401 and 1044 in ATP sites of human P-glycoprotein are critical for ATP binding and hydrolysis: evidence for a conserved subdomain, the A-loop in the ATP-binding cassette.
    Biochemistry, Vol. 45, No. 24. (20 June 2006), pp. 7605-7616.
    by IW Kim, XH Peng, ZE Sauna, PC FitzGerald, D Xia, M Müller, K Nandigama, SV Ambudkar
    posted to mutants pgp abcb1 pgpmuts by happy_manatee on 2006-11-21 19:00:53 as **
  • Cystic fibrosis-type mutational analysis in the ATP-binding cassette transporter signature of human P-glycoprotein MDR1.
    J Biol Chem, Vol. 269, No. 32. (12 August 1994), pp. 20575-20583.
    by T Hoof, A Demmer, MR Hadam, JR Riordan, B Tümmler
    posted to abcb1 mutants pgp pgpmuts by happy_manatee on 2006-11-21 01:54:00 as **
  • P-glycoprotein function involves conformational transitions detectable by differential immunoreactivity
    PNAS, Vol. 94, No. 24. (25 November 1997), pp. 12908-12913.
    by Eugene B Mechetner, Brigitte Schott, Brian S Morse, Wilfred D Stein, Todd Druley, Kenneth A Davis, Takashi Tsuruo, Igor B Roninson
    posted to abcb1 pgp uic2 by happy_manatee on 2006-11-21 01:45:40 as **
  • Functional characterization of a glycine 185-to-valine substitution in human P-glycoprotein by using a vaccinia-based transient expression system.
    Mol Biol Cell, Vol. 7, No. 10. (October 1996), pp. 1485-1498.
    by M Ramachandra, SV Ambudkar, MM Gottesman, I Pastan, CA Hrycyna
    posted to abcb1 mutants pgp pgpmuts by happy_manatee on 2006-11-21 01:44:15 as **
  • Altered drug-stimulated ATPase activity in mutants of the human multidrug resistance protein.
    J Biol Chem, Vol. 271, No. 4. (26 January 1996), pp. 1877-1883.
    by M Müller, E Bakos, E Welker, A Váradi, UA Germann, MM Gottesman, BS Morse, IB Roninson, B Sarkadi
    posted to abcb1 mutants pgp pgpmuts signature by happy_manatee on 2006-11-21 01:43:49 as **
  • Characterization of the human multidrug resistance protein containing mutations in the ATP-binding cassette signature region.
    Biochem J, Vol. 323 ( Pt 3) (1 May 1997), pp. 777-783.
    by E Bakos, I Klein, E Welker, K Szabó, M Müller, B Sarkadi, A Váradi
    posted to abcb1 mutants pgp pgpmuts signature by happy_manatee on 2006-11-21 01:43:19 as **
  • Both ATP sites of human P-glycoprotein are essential but not symmetric.
    Biochemistry, Vol. 38, No. 42. (19 October 1999), pp. 13887-13899.
    by CA Hrycyna, M Ramachandra, UA Germann, PW Cheng, I Pastan, MM Gottesman
    posted to abcb1 catalytic context cycle mdr1 mutants nbd by happy_manatee on 2006-08-09 19:46:25 as **
  • Identification of residues in the drug-binding domain of human P-glycoprotein. Analysis of transmembrane segment 11 by cysteine-scanning mutagenesis and inhibition by dibromobimane.
    J Biol Chem, Vol. 274, No. 50. (10 December 1999), pp. 35388-35392.
    by TW Loo, DM Clarke
    posted to abcb1 mdr1 mutants transmembrane by happy_manatee on 2006-08-09 19:44:45 as **
  • Conserved walker A Ser residues in the catalytic sites of P-glycoprotein are critical for catalysis and involved primarily at the transition state step.
    J Biol Chem, Vol. 275, No. 32. (11 August 2000), pp. 25031-25038.
    by IL Urbatsch, K Gimi, S Wilke-Mounts, AE Senior
    posted to abcb1 carboxylate catalytic mdr1 mutants pgp by happy_manatee on 2006-08-09 19:43:29 as **
  • Identification of basic residues involved in drug export function of human multidrug resistance-associated protein 2.
    J Biol Chem, Vol. 275, No. 50. (15 December 2000), pp. 39617-39624.
    by S Ryu, T Kawabe, S Nada, A Yamaguchi
    posted to abcb1 mdr1 mutants pgp transmembrane by happy_manatee on 2006-08-09 19:41:44 as **
  • Identification of residues within the drug-binding domain of the human multidrug resistance P-glycoprotein by cysteine-scanning mutagenesis and reaction with dibromobimane.
    J Biol Chem, Vol. 275, No. 50. (15 December 2000), pp. 39272-39278.
    by TW Loo, DM Clarke
    posted to abcb1 mdr1 mutants pgp transmembrane by happy_manatee on 2006-08-09 19:40:57 as **
  • Role of glycine-534 and glycine-1179 of human multidrug resistance protein (MDR1) in drug-mediated control of ATP hydrolysis.
    Biochem J, Vol. 356, No. Pt 1. (15 May 2001), pp. 71-75.
    by G Szakács, C Ozvegy, E Bakos , B Sarkadi, A Váradi
    posted to abcb1 mdr1 mutants pgp pgpmuts signature by happy_manatee on 2006-08-09 19:39:36 as **
  • Functional Characterization of Coding Polymorphisms in the Human MDR1 Gene Using a Vaccinia Virus Expression System
    Mol Pharmacol, Vol. 62, No. 1. (1 July 2002), pp. 1-6.
    by Chava Kimchi-Sarfaty, John J Gribar, Michael M Gottesman
    posted to abcb1 mdr1 mutants pgp by happy_manatee on 2006-08-09 19:37:10 as **
  • Importance of the conserved Walker B glutamate residues, 556 and 1201, for the completion of the catalytic cycle of ATP hydrolysis by human P-glycoprotein (ABCB1).
    Biochemistry, Vol. 41, No. 47. (26 November 2002), pp. 13989-14000.
    by ZE Sauna, M Müller, XH Peng, SV Ambudkar
    posted to abcb1 carboxylate mdr1 mutants pgp by happy_manatee on 2006-08-08 23:51:52 as **
  • Rescue of Folding Defects in ABC Transporters Using Pharmacological Chaperones
    Journal of Bioenergetics and Biomembranes, Vol. 37, No. 6. (December 2005), pp. 501-507.
    by Loo, Tip, Bartlett, , Clarke, David
    posted to abcb1 mdr1 pgp processing by happy_manatee on 2006-08-08 23:01:16 as **
  • The human multidrug resistance P-glycoprotein is inactive when its maturation is inhibited: potential for a role in cancer chemotherapy.
    FASEB J, Vol. 13, No. 13. (October 1999), pp. 1724-1732.
    by TW Loo, DM Clarke
    posted to abcb1 glycosylation pgp by happy_manatee on 2006-08-08 22:52:57 as **
  • Functional Characterization of Glycosylation-Deficient Human P-Glycoprotein Using A Vaccinia Virus Expression System
    Journal of Membrane Biology, Vol. 173, No. 3. (February 2000), pp. 203-214.
    by JJ Gribar, M Ramachandra, CA Hrycyna, S Dey, SV Ambudkar
    posted to abcb1 pgp by happy_manatee on 2006-08-08 22:25:17 as **
  • Targeting multidrug resistance in cancer
    Nature Reviews Drug Discovery, Vol. 5, No. 3., pp. 219-234.
    by Gergely Szakács, Jill K Paterson, Joseph A Ludwig, Catherine Booth-Genthe, Michael M Gottesman
    posted to abcb1 abcpaper1 cancer mdr resistance by happy_manatee on 2006-04-24 19:06:37 as ** along with 1 person Petersarkies
  • Processing mutations located throughout the human multidrug resistance P-glycoprotein disrupt interactions between the nucleotide binding domains.
    J Biol Chem, Vol. 279, No. 37. (10 September 2004), pp. 38395-38401.
    by TW Loo, MC Bartlett, DM Clarke
    posted to abcb1 interface mdr1 mutants nbd pgp psb by happy_manatee on 2006-03-23 22:32:36 as **
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