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happy_manatees library [145 articles]

Neue Artikel in happy_manatees Bibliothek.
  • Characterization and Classification of ATP-binding Cassette Transporter ABCA3 Mutants in Fatal Surfactant Deficiency
    J. Biol. Chem., Vol. 281, No. 45. (10 November 2006), pp. 34503-34514.
    by Yoshihiro Matsumura, Nobuhiro Ban, Kazumitsu Ueda, Nobuya Inagaki
    posted to mutants abca by happy_manatee on 2008-06-24 20:32:52 as ** along with 1 person EvaKaltenborn
  • Prediction of the phenotypic effects of non-synonymous single nucleotide polymorphisms using structural and evolutionary information
    Bioinformatics, Vol. 21, No. 10. (15 May 2005), pp. 2185-2190.
    by Lei Bao, Yan Cui
    posted to snppredict prediction mutants abcpaper1 by happy_manatee on 2008-06-24 19:48:53 as **
  • Deleterious SNP prediction: be mindful of your training data!
    Bioinformatics, Vol. 23, No. 6. (15 March 2007), pp. 664-672.
    by Care, A Matthew, Needham, J Chris, Bulpitt, J Andrew, Westhead, R David
    posted to variants uniprot prediction abcpaper1 by happy_manatee on 2008-06-24 00:07:30 as ** along with 3 people and 2 groups marcius penka Yumyai BioinfoCIPF SGU-CIPF
  • The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints.
    Mol Pharmacol, Vol. 63, No. 6. (June 2003), pp. 1256-1272.
    by R Fredriksson, MC Lagerström, LG Lundin, HB Schiöth
    posted to csmp gpcrs superfamily by happy_manatee on 2008-04-21 00:46:23 as ** along with 2 people and 1 group xdeupi adamsdi LabCompMed
  • High-throughput fluorescent-based optimization of eukaryotic membrane protein overexpression and purification in Saccharomyces cerevisiae
    PNAS, Vol. 104, No. 35. (28 August 2007), pp. 13936-13941.
    by Simon Newstead, Hyun Kim, Gunnar von Heijne, So Iwata, David Drew
    posted to csmp membrane yeast by happy_manatee on 2007-11-06 21:48:49 as ** along with 1 person zwang
  • Insecticidal toxins from black widow spider venom
    Toxicon, Vol. 49, No. 4. (15 March 2007), pp. 531-549.
    by A Rohou, J Nield, YA Ushkaryov
    posted to evolution interesting ion toxin by happy_manatee on 2007-10-24 18:29:56 as **
  • Conus venoms: a rich source of novel ion channel-targeted peptides.
    Physiol Rev, Vol. 84, No. 1. (January 2004), pp. 41-68.
    by H Terlau, BM Olivera
    posted to conotoxin by happy_manatee on 2007-10-18 21:59:25 as **
  • Identification of a mammalian mitochondrial porphyrin transporter
    Nature (27 September 2006)
    by Partha C Krishnamurthy, Guoqing Du, Yu Fukuda, Daxi Sun, Janardhan Sampath, Kelly E Mercer, Junfeng Wang, Beatriz Sosa-Pineda, Gopal K Murti, John D Schuetz
    posted to abcb6 csmp membrane mitochondria by happy_manatee on 2007-09-10 17:26:04 as **
  • Crystal structure of bacterial multidrug efflux transporter AcrB.
    Nature, Vol. 419, No. 6907. (10 October 2002), pp. 587-593.
    by S Murakami, R Nakashima, E Yamashita, A Yamaguchi
    posted to csmp membrane resistance by happy_manatee on 2007-09-08 01:33:42 as ** along with 3 people martainn netterpaladin viktor21614
  • A Nucleoside Transporter from Trypanosoma brucei Involved in Drug Resistance
    Science, Vol. 285, No. 5425. (9 July 1999), pp. 242-244.
    by Pascal Mäser, Christine Sütterlin, Anastasia Kralli, Ronald Kaminsky
    posted to csmp membrane multidrug resistance by happy_manatee on 2007-09-08 01:10:23 as **
  • Differences in trans-stimulated chloroquine efflux kinetics are linked to PfCRT in Plasmodium falciparum
    Molecular Microbiology, Vol. 64, No. 2. (April 2007), pp. 407-420.
    by Sanchez, P Cecilia, Rohrbach, Petra, Mclean, E Jeremy, Fidock, A David, Stein, D Wilfred, Lanzer, Michael
    posted to csmp membrane resistance by happy_manatee on 2007-09-08 00:22:58 as **
  • Roles for the Trypanosoma brucei P2 Transporter in DB75 Uptake and Resistance
    Mol Pharmacol, Vol. 70, No. 5. (1 November 2006), pp. 1585-1592.
    by Charlotte A Lanteri, Mhairi L Stewart, Janice M Brock, Vincent P Alibu, Steven R Meshnick, Richard R Tidwell, Michael P Barrett
    posted to csmp disease membrane by happy_manatee on 2007-09-08 00:13:29 as **
  • The progress of membrane protein structure determination.
    Protein Sci, Vol. 13, No. 7. (July 2004), pp. 1948-1949.
    by SH White
    posted to csmp membrane review by happy_manatee on 2007-09-07 23:49:59 as ** along with 1 person thaliana
  • THE DRUGGABLE GENOME
    Nat Rev Drug Discov, Vol. 1, No. 9. (2002), pp. 727-730.
    by Andrew L Hopkins, Colin R Groom
    posted to csmp membrane review by happy_manatee on 2007-09-07 23:02:11 as ** along with 5 people and 2 groups Yanno andreasauerwein marcius Nambi ramensky BioinfoCIPF SGU-CIPF
  • The 7 TM G-Protein-Coupled Receptor Target Family
    ChemMedChem, Vol. 1, No. 8. (2006), pp. 760-782.
    by Edgar Jacoby, Rochdi Bouhelal, Marc Gerspacher, Klaus Seuwen
    posted to csmp membrane review by happy_manatee on 2007-09-07 23:01:49 as ** along with 2 people IrinaMoreira cen4ik
  • 3-D structural and functional characterization of the purified KATP channel complex Kir6.2[ndash]SUR1
    The EMBO Journal, Vol. aop, No. current. (24 November 2005)
    by Michael V Mikhailov, Jeff D Campbell, Heidi de Wet, Kenju Shimomura, Brittany Zadek, Richard F Collins, Mark SP Sansom, Robert C Ford, Frances M Ashcroft
    posted to abcc9 channel csmp sur1 sur2 by happy_manatee on 2007-08-27 18:14:32 as **
  • Identification of Essential Amino Acid Residues of the NorM Na+/Multidrug Antiporter in Vibrio parahaemolyticus
    J. Bacteriol., Vol. 187, No. 5. (1 March 2005), pp. 1552-1558.
    by Masato Otsuka, Makoto Yasuda, Yuji Morita, Chie Otsuka, Tomofusa Tsuchiya, Hiroshi Omote, Yoshinori Moriyama
    posted to csmp mate_family membrane multidrug mutants by happy_manatee on 2007-08-06 22:05:18 as **
  • Analysis of the topology of Vibrio cholerae NorM and identification of amino acid residues involved in norfloxacin resistance.
    Antimicrob Agents Chemother, Vol. 50, No. 11. (November 2006), pp. 3717-3723.
    by AK Singh, R Haldar, D Mandal, M Kundu
    posted to csmp mate_family membrane multidrug mutants by happy_manatee on 2007-08-06 21:08:28 as **
  • Differential contribution of organic cation transporters, OCT2 and MATE1, in platinum agent-induced nephrotoxicity
    Biochemical Pharmacology, Vol. 74, No. 3. (1 August 2007), pp. 477-487.
    by Sachiko Yokoo, Atsushi Yonezawa, Satohiro Masuda, Atsushi Fukatsu, Toshiya Katsura, Ken-Ichi Inui
    posted to csmp mate_family membrane multidrug mutants by happy_manatee on 2007-08-06 20:25:07 as **
  • Polyspecific Organic Cation Transporters: Structure, Function, Physiological Roles, and Biopharmaceutical Implications
    Pharmaceutical Research, Vol. 24, No. 7. (July 2007), pp. 1227-1251.
    by Koepsell, Hermann, Lips, Katrin, Volk, Christopher
    posted to csmp mate_family membrane multidrug mutants by happy_manatee on 2007-08-06 19:34:57 as **
  • Translocation of lipid-linked oligosaccharides across the ER membrane requires Rft1 protein
    Nature, Vol. 415, No. 6870. (24 January 2002), pp. 447-450.
    by Jonne Helenius, Davis T Ng, Cristina L Marolda, Peter Walter, Miguel A Valvano, Markus Aebi
    posted to csmp membrane multidrug mutants rft1_family by happy_manatee on 2007-08-06 18:02:55 as **
  • Molecular cloning, functional characterization and tissue distribution of rat H+/organic cation antiporter MATE1.
    Pharm Res, Vol. 23, No. 8. (August 2006), pp. 1696-1701.
    by T Terada, S Masuda, J Asaka, M Tsuda, T Katsura, K Inui
    posted to csmp mate_family membrane multidrug mutants by happy_manatee on 2007-08-06 18:00:29 as **
  • A human transporter protein that mediates the final excretion step for toxic organic cations.
    Proc Natl Acad Sci U S A, Vol. 102, No. 50. (13 December 2005), pp. 17923-17928.
    by M Otsuka, T Matsumoto, R Morimoto, S Arioka, H Omote, Y Moriyama
    posted to csmp mate_family membrane by happy_manatee on 2007-08-06 17:53:01 as **
  • Identification of essential histidine and cysteine residues of the H+/organic cation antiporter multidrug and toxin extrusion (MATE).
    Mol Pharmacol, Vol. 71, No. 6. (June 2007), pp. 1487-1493.
    by J Asaka, T Terada, M Tsuda, T Katsura, K Inui
    posted to csmp mate_family membrane multidrug mutants by happy_manatee on 2007-08-06 17:28:13 as **
  • Structural genomics for membrane proteins.
    Cell Mol Life Sci, Vol. 63, No. 22. (November 2006), pp. 2597-2607.
    by K Lundstrom
    posted to csmp membrane structure by happy_manatee on 2007-08-06 16:27:33 as **
  • Portrait of multifaceted transporter, the multidrug resistance-associated protein 1 (MRP1/ABCC1)
    Pflügers Archiv, Vol. 453, No. 5. (February 2007), pp. 621-641.
    by Bakos, Eva, Homolya, Laszlo
    posted to abcc1 mrp1 review by happy_manatee on 2007-03-11 20:49:41 as **
  • Flow cytometry-based approach to ABCG2 function suggests that the transporter differentially handles the influx and efflux of drugs.
    Cytometry A, Vol. 62, No. 2. (December 2004), pp. 129-138.
    by M García-Escarp, V Martínez-Muñoz, I Sales-Pardo, J Barquinero, JC Domingo, P Marin, J Petriz
    posted to 482 abcg2 facs kinetics mutant by happy_manatee on 2007-03-07 02:18:16 as **
  • Mutations at amino-acid 482 in the ABCG2 gene affect substrate and antagonist specificity.
    Br J Cancer, Vol. 89, No. 10. (17 November 2003), pp. 1971-1978.
    by RW Robey, Y Honjo, K Morisaki, TA Nadjem, S Runge, M Risbood, MS Poruchynsky, SE Bates
    posted to 482 abcg2 facs mutant by happy_manatee on 2007-03-07 02:17:28 as **
  • Structure of a bacterial multidrug ABC transporter
    Nature (30 August 2006)
    by Roger JP Dawson, Kaspar P Locher
    posted to 2hyd complete_stx locher sav1866 by happy_manatee on 2007-03-05 19:32:00 as ** along with 2 people netterpaladin softsimu
  • Structure of an ABC transporter in complex with its binding protein
    Nature (25 February 2007)
    by Kaspar Hollenstein, Dominik C Frei, Kaspar P Locher
    posted to complete_stx locher multidrug structure by happy_manatee on 2007-03-05 19:26:36 as ** along with 3 people netterpaladin EvaKaltenborn softsimu
  • Overview: ABC Transporters and Human Disease
    Journal of Bioenergetics and Biomembranes, Vol. V33, No. 6. (1 December 2001), pp. 453-458.
    by Michael M Gottesman, Suresh V Ambudkar
    posted to disease review by happy_manatee on 2007-03-05 18:19:22 as ** along with 1 person softsimu
  • Re-evaluation and functional classification of non-synonymous single nucleotide polymorphisms of the human ATP-binding cassette transporter ABCG2.
    Cancer Sci, Vol. 98, No. 2. (February 2007), pp. 231-239.
    by A Tamura, K Wakabayashi, Y Onishi, M Takeda, Y Ikegami, S Sawada, M Tsuji, Y Matsuda, T Ishikawa
    posted to abcg2 bcrp functional variants by happy_manatee on 2007-03-02 01:26:38 as **
  • Functional analysis of the human variants of breast cancer resistance protein: I206L, N590Y, and D620N.
    Drug Metab Dispos, Vol. 33, No. 6. (June 2005), pp. 697-705.
    by RR Vethanayagam, H Wang, A Gupta, Y Zhang, F Lewis, JD Unadkat, Q Mao
    posted to abcg2 bcrp functional variants by happy_manatee on 2007-03-02 00:53:38 as **
  • Functional analysis of SNPs variants of BCRP/ABCG2.
    Pharm Res, Vol. 21, No. 10. (October 2004), pp. 1895-1903.
    by C Kondo, H Suzuki, M Itoda, S Ozawa, J Sawada, D Kobayashi, I Ieiri, K Mine, K Ohtsubo, Y Sugiyama
    posted to abcg2 bcrp functional variants by happy_manatee on 2007-03-02 00:49:43 as **
  • The apical conjugate efflux pump ABCC2 (MRP2)
    Pflügers Archiv, Vol. 453, No. 5. (February 2007), pp. 643-659.
    by Nies, Anne, Keppler, Dietrich
    posted to abcc2 abcpaper1 functional mrp2 by happy_manatee on 2007-03-01 23:44:55 as **
  • Functional characterization of non-synonymous single nucleotide polymorphisms in the gene encoding human multidrug resistance protein 1 (MRP1/ABCC1).
    Pharmacogenet Genomics, Vol. 15, No. 9. (September 2005), pp. 647-657.
    by IJ Létourneau, RG Deeley, SP Cole
    posted to abcc1 functional mrp1 mutant by happy_manatee on 2007-03-01 22:55:24 as ** along with 1 person ramensky
  • Functional validation of the genetic polymorphisms of human ATP-binding cassette (ABC) transporter ABCG2: identification of alleles that are defective in porphyrin transport.
    Mol Pharmacol, Vol. 70, No. 1. (July 2006), pp. 287-296.
    by A Tamura, M Watanabe, H Saito, H Nakagawa, T Kamachi, I Okura, T Ishikawa
    posted to transporter transmembrane atpase abcg2 by happy_manatee on 2007-01-22 22:26:08 as **
  • Mutational analysis of the MRP2 gene and long-term follow-up of Dubin-Johnson syndrome in Japan.
    J Gastroenterol, Vol. 40, No. 4. (April 2005), pp. 366-370.
    by I Machida, S Wakusawa, F Sanae, H Hayashi, A Kusakabe, H Ninomiya, M Yano, K Yoshioka
    posted to r393w mutant mrp2 abcc2 by happy_manatee on 2007-01-17 17:45:03 as **
  • Insertion of an arginine residue into the transmembrane segments corrects protein misfolding.
    J Biol Chem, Vol. 281, No. 40. (6 October 2006), pp. 29436-29440.
    by TW Loo, MC Bartlett, DM Clarke
    posted to processing folding abcb1 by happy_manatee on 2007-01-17 17:40:18 as ** along with 1 person softsimu
  • Hsp90 cochaperone Aha1 downregulation rescues misfolding of CFTR in cystic fibrosis.
    Cell, Vol. 127, No. 4. (17 November 2006), pp. 803-815.
    by X Wang, J Venable, P LaPointe, DM Hutt, AV Koulov, J Coppinger, C Gurkan, W Kellner, J Matteson, H Plutner, JR Riordan, JW Kelly, JR Yates, WE Balch
    posted to cftr folding interaction interesting by happy_manatee on 2007-01-08 19:26:12 as **
  • Ancient and Recent Positive Selection Transformed Opioid cis-Regulation in Humans.
    PLoS Biol, Vol. 3, No. 12. (15 November 2005)
    by Matthew V V Rockman, Matthew W W Hahn, Nicole Soranzo, Fritz Zimprich, David B B Goldstein, Gregory A A Wray
    posted to interesting regulation by happy_manatee on 2007-01-08 17:33:22 as ** along with 8 people and 3 groups jphekman imouthesmp indigoviolet dpollard Archaeogenetics djkt mgaldzic cisevol EisenLab CHIP cis-regulatory-evolution
  • The nature of amino acid 482 of human ABCG2 affects substrate transport and ATP hydrolysis but not substrate binding
    Protein Sci, Vol. 15, No. 7. (1 July 2006), pp. 1597-1607.
    by Karin F Ejendal, Ndeye K Diop, Linda C Schweiger, Christine A Hrycyna
    posted to abcg2 by happy_manatee on 2006-12-24 22:50:49 as **
  • Transmembrane transport of endo- and xenobiotics by mammalian ATP-binding cassette multidrug resistance proteins.
    Physiol Rev, Vol. 86, No. 3. (July 2006), pp. 849-899.
    by RG Deeley, C Westlake, SP Cole
    posted to abcc1 abcc2 abcc6 abcc9 mrp1 mrp2 review by happy_manatee on 2006-12-24 22:48:28 as **
  • Promiscuity in multidrug recognition and transport: the bacterial MFS Mdr transporters
    Molecular Microbiology, Vol. 61, No. 2. (July 2006), pp. 277-284.
    by Lewinson, Oded, Adler, Julia, Sigal, Nadejda, Bibi, Eitan
    posted to mdr promiscuity transmembrane transporter by happy_manatee on 2006-12-24 22:45:51 as ** along with 1 person EvaKaltenborn
  • The Amino Terminus of the Human Multidrug Resistance Transporter ABCC1 Has a U-shaped Folding with a Gating Function
    J. Biol. Chem., Vol. 281, No. 41. (13 October 2006), pp. 31152-31163.
    by Qun Chen, Youyun Yang, Lang Li, Jian-Ting Zhang
    posted to abcc1 transmembrane by happy_manatee on 2006-12-24 22:40:40 as **
  • Sequence alignment and homology threading reveals prokaryotic and eukaryotic proteins similar to lactose permease.
    J Mol Biol, Vol. 358, No. 4. (12 May 2006), pp. 1060-1070.
    by VN Kasho, IN Smirnova, HR Kaback
    posted to csmp by happy_manatee on 2006-11-29 20:16:16 as **
  • The multidrug transporter, P-glycoprotein, actively mediates cholesterol redistribution in the cell membrane
    PNAS, Vol. 99, No. 16. (6 August 2002), pp. 10347-10352.
    by Alexia Garrigues, Alexandre E Escargueil, Stephane Orlowski
    posted to abcb1 mutants pgp pgpmuts by happy_manatee on 2006-11-28 20:06:42 as **
  • Location of the rhodamine-binding site in the human multidrug resistance P-glycoprotein.
    J Biol Chem, Vol. 277, No. 46. (15 November 2002), pp. 44332-44338.
    by TW Loo, DM Clarke
    posted to abcb1 mutants pgp pgpmuts by happy_manatee on 2006-11-28 20:02:58 as **
  • The dileucine motif at the COOH terminus of human multidrug resistance P-glycoprotein is important for folding but not activity.
    J Biol Chem, Vol. 280, No. 4. (28 January 2005), pp. 2522-2528.
    by TW Loo, MC Bartlett, DM Clarke
    posted to abcb1 mutants pgp pgpmuts by happy_manatee on 2006-11-28 19:59:44 as **
  • The conserved tyrosine residues 401 and 1044 in ATP sites of human P-glycoprotein are critical for ATP binding and hydrolysis: evidence for a conserved subdomain, the A-loop in the ATP-binding cassette.
    Biochemistry, Vol. 45, No. 24. (20 June 2006), pp. 7605-7616.
    by IW Kim, XH Peng, ZE Sauna, PC FitzGerald, D Xia, M Müller, K Nandigama, SV Ambudkar
    posted to mutants pgp abcb1 pgpmuts by happy_manatee on 2006-11-21 19:00:53 as **
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