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20 aa aa-aa aa-coevolution aa-substitution-matric adaption adaptive and antig architecture bias bond bonding bootstrap calculatedivergencetimeforinfluenzaa cancer cluster code coevolution coevolution-rna-rate coordiated-evolution-hcv correlated correlation ctmp detecting distance drug-design dynamics ecology estimating-selection-pressure evolution evolution-of-network for gene genetic genomic h3n2 ha ha1 hierarchical hiv human hydrogen influenza influenza-seasonality interaction interactioncoevolution interactome mcbasc measure method mutation mutation-network natural-selection negative netative network neutral new nonsynonymous number of on organelle positive predicting prediction pressure protein questions receptor-ligand review---evolution seasonality-influenza selection selection-pressure substitution synonymous synthetic-biology the to usage vaccine variants viewtreej yangziheng

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