An overview of the structures of protein-DNA complexes.

by: NM Luscombe, SE Austin, HM Berman, JM Thornton

Genome Biol, Vol. 1, No. 1. (2000)

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Abstract

On the basis of a structural analysis of 240 protein-DNA complexes contained in the Protein Data Bank (PDB), we have classified the DNA-binding proteins involved into eight different structural/functional groups, which are further classified into 54 structural families. Here we present this classification and review the functions, structures and binding interactions of these protein-DNA complexes.

@article{citeulike:558739, abstract = {On the basis of a structural analysis of 240 protein-DNA complexes contained in the Protein Data Bank (PDB), we have classified the DNA-binding proteins involved into eight different structural/functional groups, which are further classified into 54 structural families. Here we present this classification and review the functions, structures and binding interactions of these protein-DNA complexes.}, address = {Biomolecular Structure and Modelling Unit, Department of Biochemistry and Molecular Biology, University College, Gower Street, London WC1E 6BT, UK. nick@biochem.ucl.ac.uk}, author = {Luscombe, N. M. and Austin, S. E. and Berman, H. M. and Thornton, J. M. }, citeulike-article-id = {558739}, issn = {1465-6914}, journal = {Genome Biol}, keywords = {cis\_regulatory\_elements, dna-protein\_interaction, review}, number = {1}, posted-at = {2008-01-01 20:29:41}, priority = {2}, title = {An overview of the structures of protein-DNA complexes.}, url = {http://view.ncbi.nlm.nih.gov/pubmed/11104519}, volume = {1}, year = {2000} }

RIS record

TY - JOUR ID - citeulike:558739 L3 - citeulike-article-id:558739 TI - An overview of the structures of protein-DNA complexes. JF - Genome Biol VL - 1 IS - 1 AD - Biomolecular Structure and Modelling Unit, Department of Biochemistry and Molecular Biology, University College, Gower Street, London WC1E 6BT, UK. nick@biochem.ucl.ac.uk SN - 1465-6914 N2 - On the basis of a structural analysis of 240 protein-DNA complexes contained in the Protein Data Bank (PDB), we have classified the DNA-binding proteins involved into eight different structural/functional groups, which are further classified into 54 structural families. Here we present this classification and review the functions, structures and binding interactions of these protein-DNA complexes. KW - cis_regulatory_elements KW - dna-protein_interaction KW - review AU - Luscombe, NM AU - Austin, SE AU - Berman, HM AU - Thornton, JM PY - 2000/// UR - http://view.ncbi.nlm.nih.gov/pubmed/11104519 ER -

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