Experimental Evolution of Olfactory Memory in Drosophila melanogaster.

@article{citeulike:1388294, abstract = {In order to address the nature of genetic variation in learning performance, we investigated the response to classical olfactory conditioning in "high-learning" Drosophila melanogaster lines previously subject to selection for the ability to learn an association between the flavor of an oviposition medium and bitter taste. In a T-maze choice test, the seven high-learning lines were better at avoiding an odor previously associated with aversive mechanical shock than were five unselected "low-learning" lines originating from the same natural population. Thus, the evolved improvement in learning ability of high-learning lines generalized to another aversion learning task involving a different aversive stimulus (shock instead of bitter taste) and a different behavioral context than that used to impose selection. In this olfactory shock task, the high-learning lines showed improvements in the learning rate as well as in two forms of consolidated memory: anesthesia-resistant memory and long-term memory. Thus, genetic variation underlying the experimental evolution of learning performance in the high-learning lines affected several phases of memory formation in the course of olfactory aversive learning. However, the two forms of consolidated memory were negatively correlated among replicate high-learning lines, which is consistent with a recent hypothesis that these two forms of consolidated memory are antagonistic.}, address = {Department of Biology, University of Fribourg, Chemin du Musee 10, CH-1700 Fribourg, Switzerland. tadeusz.kawecki@unifr.ch.}, author = {Kawecki, T. J. and Pont, J. and Preat, T. and Mery, F. }, citeulike-article-id = {1388294}, doi = {http://dx.doi.org/10.1086/518014}, issn = {1522-2152}, journal = {Physiol Biochem Zool}, keywords = {adaptation, dan\_presented, drosophila, eisen\_journal\_club, experimental\_evolution, round\_robin, selection}, number = {4}, pages = {399--405}, posted-at = {2007-06-13 21:50:16}, priority = {2}, title = {Experimental Evolution of Olfactory Memory in Drosophila melanogaster.}, url = {http://dx.doi.org/10.1086/518014}, volume = {80}, year = {2007} }

TY - JOUR ID - citeulike:1388294 L3 - citeulike-article-id:1388294 TI - Experimental Evolution of Olfactory Memory in Drosophila melanogaster. JF - Physiol Biochem Zool VL - 80 IS - 4 SP - 399 EP - 405 AD - Department of Biology, University of Fribourg, Chemin du Musee 10, CH-1700 Fribourg, Switzerland. tadeusz.kawecki@unifr.ch. SN - 1522-2152 N2 - In order to address the nature of genetic variation in learning performance, we investigated the response to classical olfactory conditioning in "high-learning" Drosophila melanogaster lines previously subject to selection for the ability to learn an association between the flavor of an oviposition medium and bitter taste. In a T-maze choice test, the seven high-learning lines were better at avoiding an odor previously associated with aversive mechanical shock than were five unselected "low-learning" lines originating from the same natural population. Thus, the evolved improvement in learning ability of high-learning lines generalized to another aversion learning task involving a different aversive stimulus (shock instead of bitter taste) and a different behavioral context than that used to impose selection. In this olfactory shock task, the high-learning lines showed improvements in the learning rate as well as in two forms of consolidated memory: anesthesia-resistant memory and long-term memory. Thus, genetic variation underlying the experimental evolution of learning performance in the high-learning lines affected several phases of memory formation in the course of olfactory aversive learning. However, the two forms of consolidated memory were negatively correlated among replicate high-learning lines, which is consistent with a recent hypothesis that these two forms of consolidated memory are antagonistic. KW - adaptation KW - dan_presented KW - drosophila KW - eisen_journal_club KW - experimental_evolution KW - round_robin KW - selection AU - Kawecki, TJ AU - Pont, J AU - Preat, T AU - Mery, F PY - 2007///g UR - http://dx.doi.org/10.1086/518014 ER -