Primary immunodeficiency diseases: an update from the International Union of Immunological Societies Primary Immunodeficiency Diseases Classification Committee Meeting in Budapest, 2005.

@article{citeulike:2961841, abstract = {Although relatively rare, primary immunodeficiency diseases (PIDs) provide an excellent window into the functioning of the immune system. In the late 1960s, observations on these diseases, with their associated infections and genetics, bisected the immune system into humoral immunity and cell-mediated immunity. These diseases also represent a challenge in their diagnosis and treatment. Beginning in 1970, a unified nomenclature for the then-known PIDs was created by a committee convoked by the World Health Organization. Since then, and later under the aegis of the International Union of Immunological Societies, an international committee of experts has met every 2 to 3 years to update the classification of PIDs. During the past 15 years, the molecular basis of more than 120 PIDs has been elucidated. This update results from the latest meeting of this committee in Budapest, Hungary, in June 2005, which followed 2 1/2 days of scientific discussions. As a result of this work, new entities have been included, and the nomenclature of some PIDs (specifically of the various forms of class-switch recombination defects, previously known as hyper-IgM syndromes) has been changed.}, address = {Department of Pediatrics, University of Brescia Spedali Civili, Italy.}, author = {Notarangelo, L. and Casanova, J. L. and Conley, M. E. and Chapel, H. and Fischer, A. and Puck, J. and Roifman, C. and Seger, R. and Geha, R. S. and }, citeulike-article-id = {2961841}, issn = {0091-6749}, journal = {The Journal of allergy and clinical immunology}, keywords = {immunodeficiency}, month = {April}, number = {4}, pages = {883--896}, posted-at = {2008-07-04 05:29:42}, priority = {2}, title = {Primary immunodeficiency diseases: an update from the International Union of Immunological Societies Primary Immunodeficiency Diseases Classification Committee Meeting in Budapest, 2005.}, url = {http://view.ncbi.nlm.nih.gov/pubmed/16680902}, volume = {117}, year = {2006} }

TY - JOUR ID - citeulike:2961841 L3 - citeulike-article-id:2961841 TI - Primary immunodeficiency diseases: an update from the International Union of Immunological Societies Primary Immunodeficiency Diseases Classification Committee Meeting in Budapest, 2005. JF - The Journal of allergy and clinical immunology VL - 117 IS - 4 SP - 883 EP - 896 AD - Department of Pediatrics, University of Brescia Spedali Civili, Italy. SN - 0091-6749 N2 - Although relatively rare, primary immunodeficiency diseases (PIDs) provide an excellent window into the functioning of the immune system. In the late 1960s, observations on these diseases, with their associated infections and genetics, bisected the immune system into humoral immunity and cell-mediated immunity. These diseases also represent a challenge in their diagnosis and treatment. Beginning in 1970, a unified nomenclature for the then-known PIDs was created by a committee convoked by the World Health Organization. Since then, and later under the aegis of the International Union of Immunological Societies, an international committee of experts has met every 2 to 3 years to update the classification of PIDs. During the past 15 years, the molecular basis of more than 120 PIDs has been elucidated. This update results from the latest meeting of this committee in Budapest, Hungary, in June 2005, which followed 2 1/2 days of scientific discussions. As a result of this work, new entities have been included, and the nomenclature of some PIDs (specifically of the various forms of class-switch recombination defects, previously known as hyper-IgM syndromes) has been changed. KW - immunodeficiency AU - Notarangelo, L AU - Casanova, JL AU - Conley, ME AU - Chapel, H AU - Fischer, A AU - Puck, J AU - Roifman, C AU - Seger, R AU - Geha, RS PY - 2006/04// UR - http://view.ncbi.nlm.nih.gov/pubmed/16680902 ER -