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Conserved noncoding sequences are reliable guides to regulatory elements

by: Ross C Hardison

Trends in Genetics, Vol. 16, No. 9. (1 September 2000), pp. 369-372.

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Abstract

A `working draft' of the human genome sequence is now available. Comparisons with the sequences of mouse and other species will be a powerful approach to identifying functional segments of the noncoding regions, such as gene regulatory elements. However, the choice of a species for most effective comparison differs among various loci.

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@article{citeulike:2396864, abstract = {A `working draft' of the human genome sequence is now available. Comparisons with the sequences of mouse and other species will be a powerful approach to identifying functional segments of the noncoding regions, such as gene regulatory elements. However, the choice of a species for most effective comparison differs among various loci.}, author = {Hardison, Ross C. }, citeulike-article-id = {2396864}, doi = {http://dx.doi.org/10.1016/S0168-9525(00)02081-3}, journal = {Trends in Genetics}, keywords = {comparative, conserved, enhancer\_finding, genomic, non-coding}, month = {September}, number = {9}, pages = {369--372}, posted-at = {2008-02-19 01:14:38}, priority = {2}, title = {Conserved noncoding sequences are reliable guides to regulatory elements}, url = {http://dx.doi.org/10.1016/S0168-9525(00)02081-3}, volume = {16}, year = {2000} }

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