Microinversions in mammalian evolution

by: MJ Chaisson, BJ Raphael, PA Pevzner

PNAS, Vol. 103, No. 52. (26 December 2006), pp. 19824-19829.

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DOI, HighWire, Pubmed, Hubmed, DOI, http://dx.doi.org/10.1073/pnas.0603984103…

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Abstract

We propose an approach for identifying microinversions across different species and show that microinversions provide a source of low-homoplasy evolutionary characters. These characters may be used as "certificates" to verify different branches in a phylogenetic tree, turning the challenging problem of phylogeny reconstruction into a relatively simple algorithmic problem. We estimate that there exist hundreds of thousands of microinversions in genomes of mammals from comparative sequencing projects, an untapped source of new phylogenetic characters. 10.1073/pnas.0603984103

@article{chaisson06, abstract = {We propose an approach for identifying microinversions across different species and show that microinversions provide a source of low-homoplasy evolutionary characters. These characters may be used as "certificates" to verify different branches in a phylogenetic tree, turning the challenging problem of phylogeny reconstruction into a relatively simple algorithmic problem. We estimate that there exist hundreds of thousands of microinversions in genomes of mammals from comparative sequencing projects, an untapped source of new phylogenetic characters. 10.1073/pnas.0603984103}, author = {Chaisson, M. J. and Raphael, B. J. and Pevzner, P. A. }, citeulike-article-id = {1030185}, doi = {http://dx.doi.org/10.1073/pnas.0603984103}, journal = {PNAS}, keywords = {microinversions, phylogenetics, phylogenomics, rare\_genomic\_characters, tree, zooseq}, month = {December}, number = {52}, pages = {19824--19829}, posted-at = {2007-01-08 14:49:39}, priority = {2}, title = {Microinversions in mammalian evolution}, url = {http://dx.doi.org/10.1073/pnas.0603984103}, volume = {103}, year = {2006} }

RIS record

TY - JOUR ID - chaisson06 L3 - citeulike-article-id:1030185 N2 - We propose an approach for identifying microinversions across different species and show that microinversions provide a source of low-homoplasy evolutionary characters. These characters may be used as "certificates" to verify different branches in a phylogenetic tree, turning the challenging problem of phylogeny reconstruction into a relatively simple algorithmic problem. We estimate that there exist hundreds of thousands of microinversions in genomes of mammals from comparative sequencing projects, an untapped source of new phylogenetic characters. 10.1073/pnas.0603984103 IS - 52 JF - PNAS EP - 19829 TI - Microinversions in mammalian evolution VL - 103 SP - 19824 KW - microinversions KW - phylogenetics KW - phylogenomics KW - rare_genomic_characters KW - tree KW - zooseq AU - Chaisson, MJ AU - Raphael, BJ AU - Pevzner, PA PY - 2006/December/26/ UR - http://dx.doi.org/10.1073/pnas.0603984103 ER -

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