Correlation between periodic sharp wave complexes and diffusion-weighted magnetic resonance images in early stage of Creutzfeldt-Jakob disease: A report of two cases.

@article{citeulike:2974016, abstract = {We evaluated the correlation between the periodic sharp wave complexes (PSWC) on EEG and the spreading lesions on diffusion-weighted (DW) magnetic resonance images (MRI) in two cases of Creutzfeldt-Jakob disease (CJD). In Case 1, DW-MRI showed increased signal intensity in bilateral caudate, bilateral parietal, and right temporo-occipital cortex at 7 weeks after onset. EEG showed PSWC of 1Hz frequency at 8 weeks after onset. Source localization analysis of the PSWC was conducted by low resolution electromagnetic tomography (LORETA), and localized the source in the cortex of bilateral parietal lobes and mesial frontal lobe, predominantly on the right side. At 10 weeks after onset, the PSWC source spread to bilateral parietal and frontal lobes, and the same spread was also observed for the lesion depicted on DW-MRI. In Case 2, DW images showed high signal intensity in the right parietal cortical lesion at 4 weeks after onset. PSWC of 2Hz frequency were seen in the routine EEG, and the source was localized in bilateral frontal lobes and right parietal lobe at 7 weeks after onset. The lesions on DW images also spread to bilateral frontal and parietal lobes. Nine weeks after onset, the source of PSWC extended to the right frontal lobe and bilateral parietal lobes, while the lesions on DW images progressed to the right temporal lobe and bilateral fronto-parieto-occipital lobes. Spreading DW-MRI lesions may correlate with the appearance of PSWC.}, address = {Department of Neurology, Nakamura Memorial Hospital, Sapporo, Japan.}, author = {Mizobuchi, Masahiro and Tanaka, Chiharu and Sako, Kazuya and Nihira, Atsuko and Abe, Takenori and Shirasawa, Atsushi }, citeulike-article-id = {2974016}, doi = {http://dx.doi.org/10.1016/j.seizure.2008.05.012}, issn = {1059-1311}, journal = {Seizure : the journal of the British Epilepsy Association}, keywords = {cjd, diagnosis, eeg, mri, prion\_diseases}, month = {July}, posted-at = {2008-07-09 02:56:59}, priority = {4}, title = {Correlation between periodic sharp wave complexes and diffusion-weighted magnetic resonance images in early stage of Creutzfeldt-Jakob disease: A report of two cases.}, url = {http://dx.doi.org/10.1016/j.seizure.2008.05.012}, year = {2008} }

TY - JOUR ID - citeulike:2974016 L3 - citeulike-article-id:2974016 N2 - We evaluated the correlation between the periodic sharp wave complexes (PSWC) on EEG and the spreading lesions on diffusion-weighted (DW) magnetic resonance images (MRI) in two cases of Creutzfeldt-Jakob disease (CJD). In Case 1, DW-MRI showed increased signal intensity in bilateral caudate, bilateral parietal, and right temporo-occipital cortex at 7 weeks after onset. EEG showed PSWC of 1Hz frequency at 8 weeks after onset. Source localization analysis of the PSWC was conducted by low resolution electromagnetic tomography (LORETA), and localized the source in the cortex of bilateral parietal lobes and mesial frontal lobe, predominantly on the right side. At 10 weeks after onset, the PSWC source spread to bilateral parietal and frontal lobes, and the same spread was also observed for the lesion depicted on DW-MRI. In Case 2, DW images showed high signal intensity in the right parietal cortical lesion at 4 weeks after onset. PSWC of 2Hz frequency were seen in the routine EEG, and the source was localized in bilateral frontal lobes and right parietal lobe at 7 weeks after onset. The lesions on DW images also spread to bilateral frontal and parietal lobes. Nine weeks after onset, the source of PSWC extended to the right frontal lobe and bilateral parietal lobes, while the lesions on DW images progressed to the right temporal lobe and bilateral fronto-parieto-occipital lobes. Spreading DW-MRI lesions may correlate with the appearance of PSWC. JF - Seizure : the journal of the British Epilepsy Association SN - 1059-1311 AD - Department of Neurology, Nakamura Memorial Hospital, Sapporo, Japan. TI - Correlation between periodic sharp wave complexes and diffusion-weighted magnetic resonance images in early stage of Creutzfeldt-Jakob disease: A report of two cases. KW - cjd KW - diagnosis KW - eeg KW - mri KW - prion_diseases AU - Mizobuchi, Masahiro AU - Tanaka, Chiharu AU - Sako, Kazuya AU - Nihira, Atsuko AU - Abe, Takenori AU - Shirasawa, Atsushi PY - 2008/07/02/ UR - http://dx.doi.org/10.1016/j.seizure.2008.05.012 ER -