Genetic basis of fitness differences in natural populations

by: Hans Ellegren, Ben C Sheldon

Nature, Vol. 452, No. 7184. (13 March 2008), pp. 169-175.

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Abstract

Genomics profoundly influences current biology. One of many exciting consequences of this revolution is the potential for identifying and studying the genetic basis of those traits affecting fitness that are key to natural selection. Recent studies using a multitude of genomic approaches have established such genotype–phenotype relationships in natural populations, giving new insight into the genetic architecture of quantitative variation. In parallel, an emerging understanding of the quantitative genetics of fitness variation in the wild means that we are poised to see a synthesis of ecological and molecular approaches in evolutionary biology.

@article{citeulike:2522348, abstract = {Genomics profoundly influences current biology. One of many exciting consequences of this revolution is the potential for identifying and studying the genetic basis of those traits affecting fitness that are key to natural selection. Recent studies using a multitude of genomic approaches have established such genotype–phenotype relationships in natural populations, giving new insight into the genetic architecture of quantitative variation. In parallel, an emerging understanding of the quantitative genetics of fitness variation in the wild means that we are poised to see a synthesis of ecological and molecular approaches in evolutionary biology.}, author = {Ellegren, Hans and Sheldon, Ben C. }, citeulike-article-id = {2522348}, doi = {http://dx.doi.org/10.1038/nature06737}, journal = {Nature}, keywords = {epidemiology, evolution, genetics, population, read, review, selection, variation}, month = {March}, number = {7184}, pages = {169--175}, posted-at = {2008-11-09 18:39:32}, priority = {2}, publisher = {Nature Publishing Group}, title = {Genetic basis of fitness differences in natural populations}, url = {http://dx.doi.org/10.1038/nature06737}, volume = {452}, year = {2008} }

RIS record

TY - JOUR ID - citeulike:2522348 L3 - citeulike-article-id:2522348 N2 - Genomics profoundly influences current biology. One of many exciting consequences of this revolution is the potential for identifying and studying the genetic basis of those traits affecting fitness that are key to natural selection. Recent studies using a multitude of genomic approaches have established such genotype–phenotype relationships in natural populations, giving new insight into the genetic architecture of quantitative variation. In parallel, an emerging understanding of the quantitative genetics of fitness variation in the wild means that we are poised to see a synthesis of ecological and molecular approaches in evolutionary biology. IS - 7184 JF - Nature EP - 175 TI - Genetic basis of fitness differences in natural populations PB - Nature Publishing Group VL - 452 SP - 169 KW - epidemiology KW - evolution KW - genetics KW - population KW - read KW - review KW - selection KW - variation AU - Ellegren, Hans AU - Sheldon, Ben PY - 2008/03/13/ UR - http://dx.doi.org/10.1038/nature06737 ER -

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