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Yannos drugdiscovery [29 articles]

Neue Publikationen in Yannos Bibliothek eingetragen unter dem Bezeichner: drugdiscovery. You can also see everyone's drugdiscovery.
  • High-throughput kinase profiling as a platform for drug discovery
    Nat Rev Drug Discov, Vol. 7, No. 5. (May 2008), pp. 391-397.
    by David M Goldstein, Nathanael S Gray, Patrick P Zarrinkar
  • High-throughput electronic biology: mining information for drug discovery
    Nature Reviews Drug Discovery, Vol. 6, No. 3., pp. 220-230.
    by William Loging, Lee Harland, Bryn Williams-Jones
  • High-content single-cell drug screening with phosphospecific flow cytometry.
    Nat Chem Biol, Vol. 4, No. 2. (February 2008), pp. 132-142.
    by PO Krutzik, JM Crane, MR Clutter, GP Nolan
    posted to drugdiscovery method screening statistics by Yanno on 2008-01-23 13:38:20 as read along with 2 people jyuh kengg
  • An efficient rapid system for profiling the cellular activities of molecular libraries
    Proceedings of the National Academy of Sciences, Vol. 103, No. 9. (28 February 2006), pp. 3153-3158.
    by Jonathan S Melnick, Jeff Janes, Sungjoon Kim, Jim Y Chang, Daniel G Sipes, Drew Gunderson, Laura Jarnes, Jason T Matzen, Michael E Garcia, Tami L Hood, Ronak Beigi, Gang Xia, Richard A Harig, Hayk Asatryan, Frank S Yan, Yingyao Zhou, Xiang-Ju Gu, Alham Saadat, Vicki Zhou, Frederick J King, Christopher M Shaw, Andrew I Su, Robert Downs, Nathanael S Gray, Peter G Schultz, Markus Warmuth, Jeremy S Caldwell
  • A quantitative analysis of kinase inhibitor selectivity
    Nature Biotechnology, Vol. 26, No. 1. (08 January 2008), pp. 127-132.
    by Mazen W Karaman, Sanna Herrgard, Daniel K Treiber, Paul Gallant, Corey E Atteridge, Brian T Campbell, Katrina W Chan, Pietro Ciceri, Mindy I Davis, Philip T Edeen, Raffaella Faraoni, Mark Floyd, Jeremy P Hunt, Daniel J Lockhart, Zdravko V Milanov, Michael J Morrison, Gabriel Pallares, Hitesh K Patel, Stephanie Pritchard, Lisa M Wodicka, Patrick P Zarrinkar
  • Discovery of Novel Targets of Quinoline Drugs in the Human Purine Binding Proteome
    Mol Pharmacol, Vol. 62, No. 6. (1 December 2002), pp. 1364-1372.
    by Paul R Graves, Jesse J Kwiek, Patrick Fadden, Rupa Ray, Klaas Hardeman, Andrew M Coley, Michael Foley, Timothy A Haystead
    posted to disease drugdiscovery hcs proteomics purine by Yanno on 2008-01-03 16:04:44 as read
  • Chemogenomics: an emerging strategy for rapid target and drug discovery
    Nat Rev Genet, Vol. 5, No. 4. (April 2004), pp. 262-275.
    by Markus Bredel, Edgar Jacoby
  • Proteins, drug targets and the mechanisms they control: the simple truth about complex networks.
    Nat Rev Drug Discov (12 October 2007)
    by Robyn P P Araujo, Lance A A Liotta, Emanuel F F Petricoin
  • Drug[mdash]target network
    Nat Biotech, Vol. 25, No. 10. (October 2007), pp. 1119-1126.
    by Muhammed A Yildirim, Kwang-Il Goh, Michael E Cusick, Albert-Laszlo Barabasi, Marc Vidal
  • Relating protein pharmacology by ligand chemistry
    Nature Biotechnology, Vol. 25, No. 2. (07 February 2007), pp. 197-206.
    by Michael J Keiser, Bryan L Roth, Blaine N Armbruster, Paul Ernsberger, John J Irwin, Brian K Shoichet
  • Global mapping of pharmacological space
    Nature Biotechnology, Vol. 24, No. 7. (13 July 2006), pp. 805-815.
    by Gaia V Paolini, Richard HB Shapland, Willem P van Hoorn, Jonathan S Mason, Andrew L Hopkins
  • PI3Kγ inhibition: towards an 'aspirin of the 21st century'?
    Nature Reviews Drug Discovery, Vol. 5, No. 11. (13 October 2006), pp. 903-918.
    by Thomas Rückle, Matthias K Schwarz, Christian Rommel
    posted to drugdiscovery inflammation kinase review target by Yanno on 2006-11-27 15:03:34 as read along with 1 person jyuh
  • High-Content Screening and Profiling of Drug Activity in an Automated Centrosome-Duplication Assay.
    Chembiochem (29 November 2004)
    by Zachary E E Perlman, Timothy J J Mitchison, Thomas U U Mayer
    posted to assay centrosome drugdiscovery by Yanno on 2006-05-28 17:32:27 as read
  • High-throughput assays for promiscuous inhibitors.
    Nat Chem Biol, Vol. 1, No. 3. (August 2005), pp. 146-148.
    by BY Feng, A Shelat, TN Doman, RK Guy, BK Shoichet
    posted to drugdiscovery inhibitor method by Yanno on 2006-05-28 17:25:16 as read
  • Pharma-entomology: when bugs become drugs
    Drug Discovery Today, Vol. 8, No. 3. (21 January 2003), pp. 107-110.
    by Jean-Luc Dimarcq, Ian Hunneyball
    posted to drugdiscovery by Yanno on 2006-05-28 17:08:46 as read
  • A small molecule–kinase interaction map for clinical kinase inhibitors
    Nature Biotechnology, Vol. 23, No. 3. (13 February 2005), pp. 329-336.
    by Miles A Fabian, William H Biggs, Daniel K Treiber, Corey E Atteridge, Mihai D Azimioara, Michael G Benedetti, Todd A Carter, Pietro Ciceri, Philip T Edeen, Mark Floyd, Julia M Ford, Margaret Galvin, Jay L Gerlach, Robert M Grotzfeld, Sanna Herrgard, Darren E Insko, Michael A Insko, Andiliy G Lai, Jean-Michel Lélias, Shamal A Mehta, Zdravko V Milanov, Anne M Velasco, Lisa M Wodicka, Hitesh K Patel, Patrick P Zarrinkar, David J Lockhart
  • Features of selective kinase inhibitors.
    Chem Biol, Vol. 12, No. 6. (June 2005), pp. 621-637.
    by ZA Knight, KM Shokat
  • The Druggable Genome
    Nat Rev Drug Discov, Vol. 1, No. 9. (2002), pp. 727-730.
    by Andrew L Hopkins, Colin R Groom
  • Enzyme family–specific and activity-based screening of chemical libraries using enzyme microarrays
    Nature Biotechnology, Vol. 23, No. 5. (10 April 2005), pp. 622-627.
    by Daniel P Funeriu, Jörg Eppinger, Lucile Denizot, Masato Miyake, Jun Miyake
    posted to chip drugdiscovery enzyme hts by Yanno on 2006-05-16 08:28:04 as read
  • Proteomic profiling of metalloprotease activities with cocktails of active-site probes
    Nat Chem Biol, Vol. 2, No. 5. (May 2006), pp. 274-281.
    by Stephan A Sieber, Sherry Niessen, Heather S Hoover, Benjamin F Cravatt
    posted to assay drugdiscovery library method protease by Yanno on 2006-05-15 14:29:37 as ***
  • Improving the hit-to-lead process: data-driven assessment of drug-like and lead-like screening hits.
    Drug Discov Today, Vol. 11, No. 3-4. (February 2006), pp. 175-180.
    posted to datamining drugdiscovery review by Yanno on 2006-03-29 15:14:45 as ** along with 1 person nicklynch
  • THE ENDOCANNABINOID SYSTEM AND ITS THERAPEUTIC EXPLOITATION
    Nat Rev Drug Discov, Vol. 3, No. 9. (2004), pp. 771-784.
    by Vincenzo D Marzo, Maurizio Bifulco, Luciano D Petrocellis
  • Chemical Rescue of a Mutant Enzyme in Living Cells
    Science, Vol. 311, No. 5765. (3 March 2006), pp. 1293-1297.
    by Yingfeng Qiao, Henrik Molina, Akhilesh Pandey, Jin Zhang, Philip A Cole
  • Integrating disease knowledge and technology to deliver protein targets and biomarkers into drug discovery projects
    Drug Discovery Today: Technologies, Vol. 2, No. 4. ( 2005), pp. 345-351.
    by Thomas E Fehniger, Thomas Laurell, Gyorgy Marko-Varga
  • Drug discovery: a historical perspective.
    Science, Vol. 287, No. 5460. (17 March 2000), pp. 1960-1964.
    by J Drews
  • The druggable genome: an update.
    Drug Discov Today, Vol. 10, No. 23-24. (December 2005), pp. 1607-1610.
    by AP Russ, S Lampel
  • Chemical Genetics and Orphan Genetic Diseases
    Chemistry & Biology, Vol. 12, No. 10. (October 2005), pp. 1063-1073.
    by Mitchell R Lunn, Brent R Stockwell
    posted to drugdiscovery orphan review by Yanno on 2006-01-31 16:34:08 as read
  • Bayesian clinical trials
    Nature Reviews Drug Discovery, Vol. 5, No. 1., pp. 27-36.
    by Donald A Berry
  • Encoded self-assembling chemical libraries
    Nat Biotech, Vol. 22, No. 5. (May 2004), pp. 568-574.
    by Samu Melkko, Jorg Scheuermann, Christoph E Dumelin, Dario Neri
    posted to chemical drugdiscovery library method by Yanno on 2005-11-24 10:27:51 as read
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