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Terkkos Backman [41 articles]

Recent papers posted to Terkkos library by the author Backman. You can also see everyones Backman.
  • Pharmacokinetic Comparison of the Potential Over-the-Counter Statins Simvastatin, Lovastatin, Fluvastatin and Pravastatin.
    Clinical pharmacokinetics, Vol. 47, No. 7. (2008), pp. 463-474.
    by PJ Neuvonen, JT Backman, M Niemi
    posted to no-tag by Terkko on 2008-06-23 10:08:13 as **
  • Effects of Gemfibrozil and Atorvastatin on the Pharmacokinetics of Repaglinide in Relation to SLCO1B1 Polymorphism.
    Clinical pharmacology and therapeutics (16 April 2008)
    by A Kalliokoski, Jt Backman, Kj Kurkinen, Pj Neuvonen, M Niemi
    posted to no-tag by Terkko on 2008-04-21 09:02:29 as **
  • The Effect of Gemfibrozil on Repaglinide Pharmacokinetics Persists for at Least 12 h After the Dose: Evidence for Mechanism-based Inhibition of CYP2C8 In Vivo.
    Clinical pharmacology and therapeutics (19 March 2008)
    by A Tornio, M Niemi, M Neuvonen, J Laitila, A Kalliokoski, Pj Neuvonen, Jt Backman
    posted to no-tag by Terkko on 2008-04-07 10:03:55 as **
  • Celecoxib is a CYP1A2 inhibitor in vitro but not in vivo.
    Eur J Clin Pharmacol (16 January 2008)
    by Marjo J Karjalainen, Pertti J Neuvonen, Janne T Backman
    posted to no-tag by Terkko on 2008-01-18 13:13:15 as **
  • Pharmacogenetics of cyclosporine in children suggests an age-dependent influence of ABCB1 polymorphisms.
    Pharmacogenet Genomics, Vol. 18, No. 2. (February 2008), pp. 77-90.
    by Samuel Fanta, Mikko Niemi, Siv Jönsson, Mats O Karlsson, Christer Holmberg, Pertti J Neuvonen, Kalle Hoppu, Janne T Backman
    posted to no-tag by Terkko on 2008-01-16 10:55:02 as **
  • Effects of gender and moderate smoking on the pharmacokinetics and effects of the CYP1A2 substrate tizanidine.
    Eur J Clin Pharmacol (23 October 2007)
    by Janne T Backman, Marika T Schröder, Pertti J Neuvonen
    posted to no-tag by Terkko on 2007-10-25 07:42:25 as **
  • Characterization of novel CYP2C8 haplotypes and their contribution to paclitaxel and repaglinide metabolism
    The Pharmacogenomics Journal, Vol. aop, No. current.
    by C Rodríguez-Antona, M Niemi, JT Backman, LI Kajosaari, PJ Neuvonen, M Robledo, M Ingelman-Sundberg
    posted to no-tag by Terkko on 2007-10-12 07:32:04 as **
  • Trimethoprim and the CYP2C8*3 allele have opposite effects on the pharmacokinetics of pioglitazone.
    Drug Metab Dispos (3 October 2007)
    by Aleksi Tornio, Mikko Niemi, Pertti J J Neuvonen, Janne T T Backman
    posted to no-tag by Terkko on 2007-10-12 07:15:06 as **
  • Developmental pharmacokinetics of ciclosporin - a population pharmacokinetic study in paediatric renal transplant candidates.
    Br J Clin Pharmacol (27 July 2007)
    by S Fanta, S Jönsson, J T T Backman, M O O Karlsson, K Hoppu
    posted to no-tag by Terkko on 2007-08-01 08:22:38 as **
  • Tolfenamic acid is a potent CYP1A2 inhibitor in vitro but does not interact in vivo: correction for protein binding is needed for data interpretation.
    Eur J Clin Pharmacol (6 July 2007)
    by Marjo J Karjalainen, Pertti J Neuvonen, Janne T Backman
    posted to no-tag by Terkko on 2007-07-24 08:07:29 as **
  • Effects of Daily Ingestion of Cranberry Juice on the Pharmacokinetics of Warfarin, Tizanidine, and Midazolam-Probes of CYP2C9, CYP1A2, and CYP3A4.
    Clin Pharmacol Ther (28 March 2007)
    by J J J Lilja, J T T Backman, P J J Neuvonen
    posted to no-tag by Terkko on 2007-04-02 10:32:40 as **
  • Stereoselective interaction between the CYP2C8 inhibitor gemfibrozil and racemic ibuprofen.
    Eur J Clin Pharmacol (27 February 2007)
    by Aleksi Tornio, Mikko Niemi, Pertti J Neuvonen, Janne T Backman
    posted to no-tag by Terkko on 2007-03-08 07:50:59 as **
  • Pharmacokinetics and bone effects of budesonide in primary biliary cirrhosis.
    Aliment Pharmacol Ther, Vol. 24, No. 11-12. (December 2006), pp. 1545-1552.
    by H Rautiainen, M Färkkilä, M Neuvonen, T Sane, AL Karvonen, H Nurmi, P Kärkkäinen, PJ Neuvonen, JT Backman
    posted to no-tag by Terkko on 2007-01-10 08:16:13 as **
  • Drug interactions with lipid-lowering drugs: Mechanisms and clinical relevance.
    Clin Pharmacol Ther, Vol. 80, No. 6. (December 2006), pp. 565-581.
    by PJ Neuvonen, M Niemi, JT Backman
    posted to no-tag by Terkko on 2006-12-22 09:42:45 as **
  • Association of genetic polymorphism in ABCC2 with hepatic multidrug resistance-associated protein 2 expression and pravastatin pharmacokinetics.
    Pharmacogenet Genomics, Vol. 16, No. 11. (November 2006), pp. 801-808.
    by Mikko Niemi, Katja A Arnold, Janne T Backman, Marja K Pasanen, Ute Gödtel-Armbrust, Leszek Wojnowski, Ulrich M Zanger, Pertti J Neuvonen, Michel Eichelbaum, Kari T Kivistö, Thomas Lang
    posted to no-tag by Terkko on 2006-10-20 08:18:03 as **
  • ROFECOXIB IS A POTENT, METABOLISM-DEPENDENT INHIBITOR OF CYP1A2 - IMPLICATIONS FOR IN VITRO PREDICTION OF DRUG INTERACTIONS.
    Drug Metab Dispos (19 September 2006)
    by Marjo J J Karjalainen, Pertti J J Neuvonen, Janne T T Backman
    posted to no-tag by Terkko on 2006-09-25 07:46:33 as **
  • Rofecoxib is a potent inhibitor of cytochrome P450 1A2: studies with tizanidine and caffeine in healthy subjects
    British Journal of Clinical Pharmacology, Vol. 62, No. 3. (September 2006), pp. 345-357.
    by Backman, T Janne, Karjalainen, J Marjo, Neuvonen, Mikko, Laitila, Jouko, Neuvonen, J Pertti
    posted to no-tag by Terkko on 2006-08-30 10:55:45 as **
  • Cyclosporine A Increases Plasma Concentrations and Effects of Repaglinide.
    Am J Transplant (25 July 2006)
    by J T T Backman, L I I Kajosaari, M Niemi, P J J Neuvonen
    posted to no-tag by Terkko on 2006-08-02 11:30:32 as **
  • Pioglitazone is Metabolised by CYP2C8 and CYP3A4 in vitro: Potential for Interactions with CYP2C8 Inhibitors
    Basic & Clinical Pharmacology & Toxicology, Vol. 99, No. 1. (July 2006), pp. 44-51.
    by Jaakkola, Tiina, Laitila, Jouko, Neuvonen, J Pertti, Backman, T Janne
    posted to no-tag by Terkko on 2006-08-02 11:12:12 as **
  • The CYP2C8 inhibitor gemfibrozil does not increase the plasma concentrations of zopiclone.
    Eur J Clin Pharmacol, Vol. 62, No. 8. (August 2006), pp. 645-651.
    by A Tornio, PJ Neuvonen, JT Backman
    posted to no-tag by Terkko on 2006-07-28 11:36:08 as **
  • Montelukast and zafirlukast do not affect the pharmacokinetics of the CYP2C8 substrate pioglitazone.
    Eur J Clin Pharmacol (3 May 2006)
    by Tiina Jaakkola, Janne T Backman, Mikko Neuvonen, Mikko Niemi, Pertti J Neuvonen
    posted to no-tag by Terkko on 2006-05-10 11:43:43 as **
  • Itraconazole, gemfibrozil and their combination markedly raise the plasma concentrations of loperamide.
    Eur J Clin Pharmacol (27 April 2006)
    by Mikko Niemi, Aleksi Tornio, Marja K Pasanen, Hanna Fredrikson, Pertti J Neuvonen, Janne T Backman
    posted to no-tag by Terkko on 2006-05-08 09:36:39 as **
  • Rifampicin is only a weak inducer of CYP1A2-mediated presystemic and systemic metabolism: studies with tizanidine and caffeine.
    Eur J Clin Pharmacol (27 April 2006)
    by Janne T Backman, Marika T Granfors, Pertti J Neuvonen
    posted to no-tag by Terkko on 2006-05-08 09:36:27 as **
  • Frequencies of single nucleotide polymorphisms and haplotypes of organic anion transporting polypeptide 1B1 SLCO1B1 gene in a Finnish population.
    Eur J Clin Pharmacol (21 April 2006)
    by Marja K Pasanen, Janne T Backman, Pertti J Neuvonen, Mikko Niemi
    posted to no-tag by Terkko on 2006-05-05 10:38:42 as **
  • Telithromycin, but not montelukast, increases the plasma concentrations and effects of the cytochrome P450 3A4 and 2C8 substrate repaglinide.
    Clin Pharmacol Ther, Vol. 79, No. 3. (March 2006), pp. 231-242.
    by LI Kajosaari, M Niemi, JT Backman, PJ Neuvonen
    posted to no-tag by Terkko on 2006-03-06 09:36:36 as **
  • Polymorphisms of COX-1 and GPVI associate with the antiplatelet effect of aspirin in coronary artery disease patients.
    Thromb Haemost, Vol. 95, No. 2. (February 2006), pp. 253-259.
    by A Lepäntalo, J Mikkelsson, JC Reséndiz, L Viiri, JT Backman, E Kankuri, PJ Karhunen, R Lassila
    posted to no-tag by Terkko on 2006-02-27 08:49:13 as **
  • Pioglitazone, an in vitro inhibitor of CYP2C8 and CYP3A4, does not increase the plasma concentrations of the CYP2C8 and CYP3A4 substrate repaglinide.
    Eur J Clin Pharmacol (31 January 2006), pp. 1-7.
    by Lauri I Kajosaari, Tiina Jaakkola, Pertti J Neuvonen, Janne T Backman
    posted to no-tag by Terkko on 2006-02-02 13:03:26 as **
  • Differential Inhibition of Cytochrome P450 3A4, 3A5 and 3A7 by Five Human Immunodeficiency Virus HIV Protease Inhibitors in vitro
    Basic & Clinical Pharmacology & Toxicology, Vol. 98, No. 1. (January 2006), pp. 79-85.
    by Marika T Granfors, Jun-Sheng Wang, Lauri I Kajosaari, Jouko Laitila, Pertti J Neuvonen, Janne T Backman
    posted to no-tag by Terkko on 2006-01-27 12:28:36 as **
  • Effect of rifampicin on the pharmacokinetics of pioglitazone
    British Journal of Clinical Pharmacology, Vol. 61, No. 1. (January 2006), pp. 70-78.
    by Tiina Jaakkola, Janne T Backman, Mikko Neuvonen, Jouko Laitila, Pertti J Neuvonen
    posted to no-tag by Terkko on 2006-01-09 10:53:02 as **
  • Effect of itraconazole on the pharmacokinetics of atenolol.
    Basic Clin Pharmacol Toxicol, Vol. 97, No. 6. (December 2005), pp. 395-398.
    by JJ Lilja, JT Backman, PJ Neuvonen
    posted to no-tag by Terkko on 2006-01-02 07:03:17 as **
  • Cyclosporine markedly raises the plasma concentrations of repaglinide.
    Clin Pharmacol Ther, Vol. 78, No. 4. (October 2005), pp. 388-399.
    by LI Kajosaari, M Niemi, M Neuvonen, J Laitila, PJ Neuvonen, JT Backman
    posted to no-tag by Terkko on 2005-10-05 11:45:13 as **
  • Oral contraceptives containing ethinyl estradiol and gestodene markedly increase plasma concentrations and effects of tizanidine by inhibiting cytochrome P450 1A2.
    Clin Pharmacol Ther, Vol. 78, No. 4. (October 2005), pp. 400-411.
    by MT Granfors, JT Backman, J Laitila, PJ Neuvonen
    posted to no-tag by Terkko on 2005-10-05 11:44:55 as **
  • Use of the levonorgestrel-releasing intrauterine system and breast cancer.
    Obstet Gynecol, Vol. 106, No. 4. (October 2005), pp. 813-817.
    by T Backman, I Rauramo, K Jaakkola, P Inki, K Vaahtera, A Launonen, M Koskenvuo
    posted to no-tag by Terkko on 2005-10-05 11:44:15 as **
  • Metabolism of Repaglinide by CYP2C8 and CYP3A4 in vitro: Effect of Fibrates and Rifampicin
    Basic & Clinical Pharmacology & Toxicology, Vol. 97, No. 4. (October 2005), pp. 249-256.
    by Lauri I Kajosaari, Jouko Laitila, Pertti J Neuvonen, Janne T Backman
    posted to no-tag by Terkko on 2005-09-27 13:04:25 as **
  • Rifampin markedly decreases and gemfibrozil increases the plasma concentrations of atorvastatin and its metabolites.
    Clin Pharmacol Ther, Vol. 78, No. 2. (August 2005), pp. 154-167.
    by JT Backman, H Luurila, M Neuvonen, PJ Neuvonen
    posted to no-tag by Terkko on 2005-08-15 12:06:41 as **
  • Coadministration of gemfibrozil and itraconazole has only a minor effect on the pharmacokinetics of the CYP2C9 and CYP3A4 substrate nateglinide
    British Journal of Clinical Pharmacology, Vol. 60, No. 2. (August 2005), pp. 208-217.
    by Mikko Niemi, Janne T Backman, Laura Juntti-Patinen, Mikko Neuvonen, Pertti J Neuvonen
    posted to no-tag by Terkko on 2005-07-28 08:09:12 as **
  • Comparison of 3-Hydroxy-3-methylglutaryl Coenzyme A (HMG-CoA) Reductase Inhibitors (Statins) as Inhibitors of Cytochrome P450 2C8
    Basic & Clinical Pharmacology & Toxicology, Vol. 97, No. 2. (August 2005), pp. 104-108.
    by Aleksi Tornio, Marja K Pasanen, Jouko Laitila, Pertti J Neuvonen, Janne T Backman
    posted to no-tag by Terkko on 2005-07-13 12:46:19 as **
  • Polymorphic organic anion transporting polypeptide 1B1 is a major determinant of repaglinide pharmacokinetics.
    Clin Pharmacol Ther, Vol. 77, No. 6. (June 2005), pp. 468-478.
    by M Niemi, JT Backman, LI Kajosaari, JB Leathart, M Neuvonen, AK Daly, M Eichelbaum, KT Kivistö, PJ Neuvonen
    posted to no-tag by Terkko on 2005-06-22 10:08:51 as **
  • Acute effects of pravastatin on cholesterol synthesis are associated with SLCO1B1 (encoding OATP1B1) haplotype *17.
    Pharmacogenet Genomics, Vol. 15, No. 5. (May 2005), pp. 303-309.
    by Mikko Niemi, Pertti J Neuvonen, Ute Hofmann, Janne T Backman, Matthias Schwab, Dieter Lütjohann, Klaus von Bergmann, Michel Eichelbaum, Kari T Kivistö
    posted to no-tag by Terkko on 2005-05-09 11:35:27 as **
  • Effect of gemfibrozil on the pharmacokinetics and pharmacodynamics of racemic warfarin in healthy subjects
    British Journal of Clinical Pharmacology, Vol. 59, No. 4. (April 2005), pp. 433-439.
    by Jari J Lilja, Janne T Backman, Pertti J Neuvonen
    posted to no-tag by Terkko on 2005-04-05 12:27:56 as **
  • Cyclosporine A monitoring - how to account for twice and three times daily dosing.
    Pediatr Nephrol (17 March 2005)
    by Samuel Fanta, Janne T Backman, Paula Seikku, Christer Holmberg, Kalle Hoppu
    posted to no-tag by Terkko on 2005-03-21 07:55:25 as **
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