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Tag target [310 articles]

Recent papers classified by the tag target.
  • MicroRNA Targeting Specificity in Mammals: Determinants beyond Seed Pairing.
    Mol Cell, Vol. 27, No. 1. (6 July 2007), pp. 91-105.
    by Andrew Grimson, Kyle Kai-How K Farh, Wendy K K Johnston, Philip Garrett-Engele, Lee P P Lim, David P P Bartel
    posted to mammal microrna prediction target by zwang on 2007-08-15 04:15:51 as ** along with 7 people and 1 group giovenko jfr andersbj bootsy heliopais fpattyn maralena microRNA
  • A protocol for constructing gene targeting vectors: generating knockout mice for the cadherin family and beyond
    Nat. Protocols, Vol. 3, No. 6. (May 2008), pp. 1056-1076.
    by Sen Wu, Guoxin Ying, Qiang Wu, Mario R Capecchi
    posted to mammal protocol target by zwang on 2008-07-04 03:36:02 as ** along with 2 people qeimmu dchughes
  • How many modes of action should an antibiotic have?
    Current Opinion in Pharmacology, Vol. 8, No. 5. (October 2008), pp. 564-573.
    by H Brotzoesterhelt, N Brunner
    posted to target resistance of mode antibiotic action by zimbo1 on 2008-11-11 10:22:14 as ** along with 1 person ramensky
  • Ligand-Target Interaction-Based Weighting of Substructures for Virtual Screening
    J. Chem. Inf. Model. (27 September 2008)
    by Thomas J Crisman, Mihiret T Sisay, Jürgen Bajorath
    posted to target scoring interaction fragment fingerprint by zimbo1 on 2008-10-06 08:09:30 as **
  • SuperTarget and Matador: resources for exploring drug-target relationships.
    Nucleic Acids Res (16 October 2007)
    by Stefan Günther, Michael Kuhn, Mathias Dunkel, Monica Campillos, Christian Senger, Evangelia Petsalaki, Jessica Ahmed, Eduardo Garcia G Urdiales, Andreas Gewiess, Lars Juhl J Jensen, Reinhard Schneider, Roman Skoblo, Robert B B Russell, Philip E E Bourne, Peer Bork, Robert Preissner
    posted to target interaction drug by zimbo1 on 2008-09-08 09:30:11 as ** along with 7 people dansullivanblk guhjy mdimmic daevans massivemayhem Evangelia larsjuhljensen
  • The problem of optimal robust sensor scheduling
    (2000)
    by A Savkin, R Evans, E Skafidas
    posted to target tracking wsn by zhensong on 2006-10-14 16:58:34 as **
  • Molecular targeted therapies for breast cancer treatment
    Breast Cancer Research, Vol. 10 (24 July 2008), 211.
    by Claus M Schlotter, Ulf Vogt, Heike Allgayer, Burkhard Brandt
    posted to therapy target molecular cancer breast by Zephyrus on 2008-10-05 20:23:18 as ** along with 1 person jfr
  • Gene Expression Profiles in Breast Cancer to Identify Estrogen Receptor Target Genes
    Mini Reviews in Medicinal Chemistry, Vol. 8, No. 5. (May 2008), pp. 448-454.
    by Nagai, , Brentani,
    posted to target receptor genes gene-expression estrogen by Zephyrus on 2008-11-30 23:52:45 as **
  • Immune cells as anti-cancer therapeutic targets and tools
    Journal of Cellular Biochemistry, Vol. 101, No. 4. (2007), pp. 918-926.
    by Magnus Johansson, Tingting Tan, Karin E de Visser, Lisa M Coussens
    posted to thesis therapy target review immune cells cancer background by Zephyrus on 2008-11-29 01:51:55 as **
  • Steroid Sulfatase: A New Target for the Endocrine Therapy of Breast Cancer
    Oncologist, Vol. 12, No. 4. (1 April 2007), pp. 370-374.
    by Susannah J Stanway, Patrick Delavault, Atul Purohit, Lawrence LW Woo, Christophe Thurieau, Barry V Potter, Michael J Reed
    posted to sulfatase therapy target steroid endocrine drug cancer breast by Zephyrus on 2008-10-14 12:51:50 as **
  • Gene expression profiles in breast cancer to identify estrogen receptor target genes.
    Mini reviews in medicinal chemistry, Vol. 8, No. 5. (May 2008), pp. 448-454.
    by MA Nagai, MM Brentani
    posted to estrogen-receptor genetics web-study target review receptor expression estrogen cancer breast by Zephyrus on 2008-07-17 01:02:44 as ** along with 1 group Breast Cancer Reading Club
  • Selective estrogen enzyme modulator actions of melatonin in human breast cancer cells
    Journal of Pineal Research, Vol. 45, No. 1. (August 2008), pp. 86-92.
    by Gonzalez, , Cos, , Martinez-Campa, , Alonso-Gonzalez, , Sanchez-Mateos, , Mediavilla, , Sanchez-Barcelo,
    posted to thesis therapy target melatonin immunomodulation estrogen enzyme drug-discovery cancer breast background by Zephyrus on 2008-11-09 18:00:55 as ** along with 1 group Breast Cancer Reading Club
  • Targeting tumour-associated macrophages
    Expert Opinion on Therapeutic Targets, Vol. 11, No. 9. (September 2007), pp. 1219-1229.
    by Antonio Sica, Luca Rubino, Alessandra Mancino, Paola Larghi, Chiara Porta, Monica Rimoldi, Graziella Solinas, Massimo Locati, Paola Allavena, Alberto Mantovani
    posted to target tumour thesis macrophage immunology by Zephyrus on 2008-10-16 23:14:35 as **
  • A critique of the molecular target-based drug discovery paradigm based on principles of metabolic control: Advantages of pathway-based discovery.
    Metab Eng (20 September 2007)
    by Marc K K Hellerstein
    posted to target drug-discovery cancer-crosstalk by Zephyrus on 2008-09-09 09:25:42 as ** along with 5 people and 2 groups guhjy barry msierk Ema cmmorel Roswell Cancer Crosstalk McCammon
  • Chemokines and Their Receptors: Drug Targets in Immunity and Inflammation.
    Annu Rev Pharmacol Toxicol (17 September 2007)
    by Antonella Viola, Andrew D D Luster
    posted to evolepi thesis target receptor inflammation immunology chemokines by Zephyrus on 2008-10-20 19:41:10 as ** along with 1 person guhjy
  • Systematic Identification of mRNAs Recruited to Argonaute 2 by Specific microRNAs and Corresponding Changes in Transcript Abundance.
    PLoS ONE, Vol. 3, No. 5. (2008)
    by DG Hendrickson, DJ Hogan, D Herschlag, JE Ferrell, PO Brown
    posted to another are at cds experimental identification mirna paper reported sites target by yuwang on 2008-05-08 20:10:58 as ** along with 4 people diaz0058 jfr bootsy maralena
  • Prioritizing Genomic Drug Targets in Pathogens: Application to Mycobacterium tuberculosis
    PLoS Computational Biology, Vol. 2, No. 6. (1 June 2006), e61.
    by Samiul Hasan, Sabine Daugelat, Srinivasa PS Rao, Mark Schreiber
    posted to target prediction by yaredo on 2008-11-17 17:02:43 as ** along with 2 people and 1 group dansullivanblk caporaso biomedical-nlp
  • Price Movements as Indicators of Tender Offer Success
    The Journal of Finance, Vol. 41, No. 2. (1986), pp. 481-499.
    by William Samuelson, Leonard Rosenthal
    posted to tender target success stock statistical prices offers movement mergers market company analysis acquisitions by yanshanxiao on 2008-09-24 00:30:21 as **
  • PI3Kγ inhibition: towards an 'aspirin of the 21st century'?
    Nature Reviews Drug Discovery, Vol. 5, No. 11. (13 October 2006), pp. 903-918.
    by Thomas Rückle, Matthias K Schwarz, Christian Rommel
    posted to drugdiscovery inflammation kinase review target by Yanno on 2006-11-27 15:03:34 as read along with 1 person guhjy
  • The purinome, a complex mix of drug and toxicity targets.
    Curr Top Med Chem, Vol. 6, No. 11. (2006), pp. 1117-1127.
    by TA Haystead
    posted to proteomics purine target by Yanno on 2008-01-02 16:43:45 as read
  • Cannabinoids Biology: The Search for New Therapeutic Targets
    Mol. Interv., Vol. 6, No. 3. (1 June 2006), pp. 149-161.
    by Christian C Felder, Amy K Dickason-Chesterfield, Steven A Moore
    posted to 2-ag anandamide cannabinoid review signalling target therapy by xico on 2007-08-28 20:03:46 as ** along with 1 group WetBiology
  • Reliability-based optimization of structural systems by adaptive target safety - Application to RC frames
    Structural Safety, Vol. 30, No. 2. (March 2008), pp. 144-161.
    by Younes Aoues, Alaa Chateauneuf
    posted to optimization reliability structural structures target by xapc2 on 2008-07-29 15:07:36 as read
  • Forkhead Box Transcription Factor FOXO3a Regulates Estrogen Receptor Alpha Expression and Is Repressed by the Her-2/neu/Phosphatidylinositol 3-Kinase/Akt Signaling Pathway
    Mol. Cell. Biol., Vol. 24, No. 19. (1 October 2004), pp. 8681-8690.
    by Shangqin Guo, Gail E Sonenshein
    posted to her2 target transcription_factor by tuck on 2006-02-07 13:54:36 as **
  • Regulation of Her2/neu promoter activity by the ETS transcription factor, ER81.
    J Cell Biochem, Vol. 86, No. 1. (2002), pp. 174-183.
    by DG Bosc, R Janknecht
    posted to her2 target transcription_factor by tuck on 2006-02-07 14:00:46 as **
  • When fish meet a trawling vessel: examining the behaviour of gadoids using a free-floating buoy and acoustic split-beam tracking
    Canadian Journal of Fisheries and Aquatic Sciences, Vol. 62, No. 10. (1 October 2005), pp. 2409-2422.
    by NO Handegard, D Tjostheim
    posted to target tracking by thorak on 2007-06-12 12:01:07 as **
  • Theoretical Studies on the Structure and Symmetry of the Transmembrane Region of Glutamatergic GluR5 Receptor
    J. Med. Chem., Vol. 51, No. 13. (10 July 2008), pp. 3765-3776.
    by Agnieszka A Kaczor, Urszula A Kijkowska-Murak, Dariusz Matosiuk
    posted to cns gpcrs mglur5 target by SuperFast on 2008-07-28 08:06:28 as **
  • A bioinformatics tool for linking gene expression profiling results with public databases of microRNA target predictions.
    RNA (New York, N.Y.) (23 September 2008)
    by Chad J J Creighton, Ankur K K Nagaraja, Samir M M Hanash, Martin M M Matzuk, Preethi H H Gunaratne
    posted to tool target software prediction microrna gene expression by Stew on 2008-10-31 09:48:09 as ** along with 6 people and 1 group ealloza guhjy giovenko druvus pengchy bootsy microRNA database
  • Genomic-scale prioritization of drug targets: the TDR Targets database
    Nature Reviews Drug Discovery, Vol. 7, No. 11. (17 October 2008), pp. 900-907.
    by Fernán Agüero, Bissan Al-Lazikani, Martin Aslett, Matthew Berriman, Frederick S Buckner, Robert K Campbell, Santiago Carmona, Ian M Carruthers, Edith AW Chan, Feng Chen, Gregory J Crowther, Maria A Doyle, Christiane Hertz-Fowler, Andrew L Hopkins, Gregg Mcallister, Solomon Nwaka, John P Overington, Arnab Pain, Gaia V Paolini, Ursula Pieper, Stuart A Ralph, Aaron Riechers, David S Roos, Andrej Sali, Dhanasekaran Shanmugam, Takashi Suzuki, Wesley C Van Voorhis, Christophe LMJ Verlinde
    posted to target drugtargets by sschurer on 2008-12-01 20:02:31 as ** along with 3 people richardbickerton guhjy tmmurali
  • ACE2: A New Target for Prevention of Diabetic Nephropathy?
    J Am Soc Nephrol, Vol. 17, No. 11. (November 2006), pp. 2957-2959.
    by JR Ingelfinger
    posted to diabetics target by skhadar on 2007-07-25 07:44:30 as ** along with 2 people guhjy brainsman2000
  • Integrated Assessment and Prediction of Transcription Factor Binding
    PLoS Computational Biology, Vol. 2, No. 6. (1 June 2006), e70.
    by Andreas Beyer, Christopher Workman, Jens Hollunder, Dörte Radke, Ulrich Möller, Thomas Wilhelm, Trey Ideker
    posted to prediction target tf transcription by samal on 2006-08-22 07:03:55 as ** along with 7 people and 1 group nklee jfr balajis wnpx emilyhare reidy Ao_Li2007 EisenLab
  • Simulation of conformational transitions by the restricted perturbation-targeted molecular dynamics method.
    J Chem Phys, Vol. 122, No. 11. (15 March 2005)
    by A van der Vaart, M Karplus
    posted to dihedrals folding md protein target transition by ruvido on 2006-12-22 11:26:26 as read along with 1 person nigham
  • In Vitro Targeting of Synthesized Antibody-Conjugated Dendrimer Nanoparticles
    Biomacromolecules, Vol. 5, No. 6. (8 November 2004), pp. 2269-2274.
    by TP Thomas, AK Patri, A Myc, MT Myaing, JY Ye, TB Norris, JR Baker
    posted to fibers dendrimers antibodies nanoparticles target two-photon by rodney on 2007-08-08 21:55:50 as ** along with 1 person and 1 group eeruowl Kopelman_Group
  • MicroRNA-21 targets tumor suppressor genes in invasion and metastasis.
    Cell Res (12 February 2008)
    by Shuomin Zhu, Hailong Wu, Fangting Wu, Daotai Nie, Shijie Sheng, Yin-Yuan Y Mo
    posted to mir-21 target by robertlsons on 2008-08-13 00:45:07 as read along with 2 people eckart_bindewald maralena
  • A structural snapshot of base-pair opening in DNA.
    Proc Natl Acad Sci U S A, Vol. 96, No. 21. (12 October 1999), pp. 11809-11814.
    by DM van Aalten, DA Erlanson, GL Verdine, L Joshua-Tor
    posted to enzyme sequence target by RaquelSL on 2007-10-24 10:30:26 as ** along with 1 group BergmanLab
  • Predicting subcellular localization of proteins based on their N-terminal amino acid sequence.
    J Mol Biol, Vol. 300, No. 4. (21 July 2000), pp. 1005-1016.
    by O Emanuelsson, H Nielsen, S Brunak, G von Heijne
    posted to tool target prediction mitotarget methodspaper localization by raiyar on 2008-09-29 13:16:43 as ** along with 4 people and 2 groups nlapalu bpcusack ana mloewer structural_bioinformatics Bioinformatics
  • Chemogenomic profiling: identifying the functional interactions of small molecules in yeast.
    Proc Natl Acad Sci U S A, Vol. 101, No. 3. (20 January 2004), pp. 793-798.
    by G Giaever, P Flaherty, J Kumm, M Proctor, C Nislow, DF Jaramillo, AM Chu, MI Jordan, AP Arkin, RW Davis
    posted to yeast target ht genomics compound by raiyar on 2007-01-19 11:36:51 as **** along with 4 people and 1 group dipenps pcahan1 balajis laureniezhang steinmetzlab
  • Drug Target Identification Using Side-Effect Similarity
    Science, Vol. 321, No. 5886. (11 July 2008), pp. 263-266.
    by Monica Campillos, Michael Kuhn, Anne-Claude Gavin, Lars J Jensen, Peer Bork
    posted to analysis chemgen compound example genomics ht interaction network prediction target by raiyar on 2008-08-11 16:21:27 as ***** along with 11 people jfr zimbo1 bpcusack jmuhlich aheilbut larsjuhljensen tmmurali askrajiv reyez roys ajaymalik
  • Adaptation of protein surfaces to subcellular location.
    Journal of molecular biology, Vol. 276, No. 2. (20 February 1998), pp. 517-525.
    by MA Andrade, SI O'Donoghue, B Rost
    posted to target proteomics prediction mitotarget methodspaper localization by raiyar on 2008-09-29 15:24:31 as read
  • Genomic profiling of drug sensitivities via induced haploinsufficiency
    Nature Genetics, Vol. 21, No. 3. (March 1999), pp. 278-283.
    by G Giaever, DD Shoemaker, TW Jones, H Liang, EA Winzeler, A Astromoff, RW Davis
    posted to yeast target ht genomics deletion compound array by raiyar on 2007-01-19 11:32:35 as **** along with 1 group steinmetzlab
  • Discovering Modes of Action for Therapeutic Compounds Using a Genome-Wide Screen of Yeast Heterozygotes
    Cell, Vol. 116, No. 1. (9 January 2004), pp. 121-137.
    by Pek Y Lum, Christopher D Armour, Sergey B Stepaniants, Guy Cavet, Maria K Wolf, Scott J Butler, Jerald C Hinshaw, Philippe Garnier, Glenn D Prestwich, Amy Leonardson
    posted to yeast target ht genomics deletion compound barcode array by raiyar on 2007-01-19 11:28:44 as **** along with 1 group steinmetzlab
  • Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.
    Plant Cell, Vol. 16, No. 1. (January 2004), pp. 241-256.
    by JL Heazlewood, JS Tonti-Filippini, AM Gout, DA Day, J Whelan, AH Millar
    posted to target proteomics prediction parts-list mitotarget mitochondria methodspaper localization by raiyar on 2008-09-29 13:05:41 as ** along with 1 person dandaman
  • Molecular Basis for Target RNA Recognition and Cleavage by Human RISC.
    Cell, Vol. 130, No. 1. (13 July 2007), pp. 101-112.
    by SL Ameres, J Martinez, R Schroeder
    posted to basis mirna molecular recognition risc target by rahulthadani on 2007-07-19 05:04:40 as ** along with 3 people and 2 groups caizhiqiang puranjoy_b f299 mgh-lcs Bioinformatics
  • Prediction of potential drug targets based on simple sequence properties
    BMC Bioinformatics, Vol. 8, No. 1. (2007)
    by Qingliang Li, Luhua Lai
    posted to drug target by qlli on 2008-04-25 09:20:58 as ** along with 1 person niallhaslam
  • Inference of Protein Complex Activities from Chemical-Genetic Profile and Its Applications: Predicting Drug-Target Pathways
    PLoS Comput Biol, Vol. 4, No. 8. (2008), e1000162.
    by Sangjo Han, Dongsup Kim
    posted to yeast target pathways factor drug analysis by ptrobajo on 2008-10-17 13:46:20 as ** along with 3 people guhjy friendpine aheilbut
  • Drug-target network
    Nat Biotech, Vol. 25, No. 10. (October 2007), pp. 1119-1126.
    by Muhammed A Yildirim, Kwang-Il Goh, Michael E Cusick, Albert-Laszlo Barabasi, Marc Vidal
    posted to target network drug by ptrobajo on 2008-10-22 21:29:08 as ** along with 13 people and 1 group richardbickerton ramensky Yanno guhjy cannin jfr julius grahamc cjeans zwang dejori mingzhi jerome_ucsf_slb libr
  • Chemogenomic profiling on a genome-wide scale using reverse-engineered gene networks
    Nature Biotechnology, Vol. 23, No. 3. (04 March 2005), pp. 377-383.
    by Diego d di Bernardo, Michael J Thompson, Timothy S Gardner, Sarah E Chobot, Erin L Eastwood, Andrew P Wojtovich, Sean J Elliott, Scott E Schaus, James J Collins
    posted to target regullatory of network mode gene drug action by ptrobajo on 2008-12-01 09:39:52 as ** along with 7 people and 2 groups rklancer snuppepuppan kentsis mjt rhem1224 balajis jayster4 TCR_Signaling SysbioMPI-TCells
  • Data completeness—the Achilles heel of drug-target networks
    Nature Biotechnology, Vol. 26, No. 9., pp. 983-984.
    by Jordi Mestres, Elisabet Gregori-Puigjané, Sergi Valverde, Ricard V Solé
    posted to target network interaction drug completeness by ptrobajo on 2008-10-17 14:46:04 as ** along with 1 person jfr
  • Complications in mammalian microRNA target prediction.
    Methods Mol Biol, Vol. 342 (2006), pp. 115-127.
    by NR Smalheiser, VI Torvik
    posted to mirna target by plofje on 2006-11-01 17:44:26 as **
  • A novel biochemical method to identify target genes of individual microRNAs: identification of a new Caenorhabditis elegans let-7 target.
    RNA (New York, N.Y.), Vol. 14, No. 11. (November 2008), pp. 2440-2451.
    by Y Andachi
    posted to target microrna biochemical_method by pengchy on 2008-11-16 00:33:38 as ** along with 1 person caizhiqiang
  • Preferential regulation of duplicated genes by microRNAs in mammals
    Genome Biology, Vol. 9, No. 8. (2008)
    by Jingjing Li, Gabriel Musso, Zhaolei Zhang
    posted to target microrna by pengchy on 2008-09-04 06:53:41 as ** along with 8 people and 2 groups jfr samgj heliopais natstreet sabahkadri djkt bpcusack fpattyn microRNA BenosLab
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