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Tag p53 [331 articles]

Recent papers classified by the tag p53.
  • Nutrient availability regulates SIRT1 through a forkhead-dependent pathway.
    Science, Vol. 306, No. 5704. (17 December 2004), pp. 2105-2108.
    by S Nemoto, MM Fergusson, T Finkel
    posted to foxo p53 sirt1 sirtuin by zhlei on 2007-11-05 20:40:35 as **
  • p53 Target Genes Sestrin1 and Sestrin2 Connect Genotoxic Stress and mTOR Signaling
    Cell, Vol. 134, No. 3. (8 August 2008), pp. 451-460.
    by Andrei V Budanov, Michael Karin
    posted to dna-damage dna-repair mtor p53 by zhlei on 2008-08-08 17:04:55 as ** along with 2 people sarahazl jyuh
  • Coordination and communication between the p53 and IGF-1-AKT-TOR signal transduction pathways
    Genes Dev., Vol. 20, No. 3. (1 February 2006), pp. 267-275.
    by Arnold J Levine, Zhaohui Feng, Tak W Mak, Han You, Shengkan Jin
    posted to akt ifg1 p53 review tor by zhlei on 2008-01-09 15:24:35 as ** along with 1 person jyuh
  • p53 in breast cancer: mutation and countermeasures.
    Frontiers in bioscience : a journal and virtual library, Vol. 12 (2007), pp. 4168-4178.
    by S Kumar, V Walia, M Ray, RC Elble
    posted to breast cancer p53 by Zephyrus on 2008-07-17 00:18:42 as **
  • WWOX tumor suppressor gene.
    Histology and histopathology, Vol. 23, No. 7. (2008), pp. 877-882.
    by J Yang, W Zhang
    posted to breast cancer p53 by Zephyrus on 2008-07-17 00:11:12 as **
  • Cytotoxic activity of 3,3',4,4',5,5'-hexahydroxystilbene against breast cancer cells is mediated by induction of p53 and downregulation of mitochondrial superoxide dismutase
    Toxicology in Vitro, Vol. 22, No. 5. (August 2008), pp. 1361-1370.
    by Marek Murias, Michal W Luczak, Anna Niepsuj, Violetta Krajka-Kuzniak, Malgorzata Zielinska-Przyjemska, Pawel P Jagodzinski, Walter Jäger, Thomas Szekeres, Jadwiga Jodynis-Liebert
    posted to breast cancer environment p53 by Zephyrus on 2008-07-17 00:23:43 as **
  • The promoters of human cell cycle genes integrate signals from two tumor suppressive pathways during cellular transformation
    Molecular Systems Biology, Vol. 1, No. 1. (18 October 2005), pp. msb4100030-E1-msb4100030-E15.
    by Yuval Tabach, Michael Milyavsky, Igor Shats, Ran Brosh, Or Zuk, Assif Yitzhaky, Roberto Mantovani, Eytan Domany, Varda Rotter, Yitzhak Pilpel
    posted to promoter p53 my motifs location by YuvalTabach on 2008-09-04 16:07:57 as **** along with 3 people rklancer jfr tuck
  • Transcriptional control of human p53-regulated genes
    Nat Rev Mol Cell Biol, Vol. 9, No. 5. (May 2008), pp. 402-412.
    by Todd Riley, Eduardo Sontag, Patricia Chen, Arnold Levine
    posted to p53 review by YuvalTabach on 2008-08-21 09:16:25 as ** along with 3 people cmzmasek lyndallsarkies oelemento
  • Aurora A, meiosis and mitosis.
    Biology of the cell / under the auspices of the European Cell Biology Organization, Vol. 96, No. 3. (April 2004), pp. 215-229.
    by R Crane, B Gadea, L Littlepage, H Wu, JV Ruderman
    posted to 20q aurka p53 tpx2 by YuvalTabach on 2008-08-03 18:05:25 as **
  • Overexpression of aurora kinase A in mouse mammary epithelium induces genetic instability preceding mammary tumor formation
    Oncogene, Vol. aop, No. current.
    by X Wang, YX Zhou, W Qiao, Y Tominaga, M Ouchi, T Ouchi, CX Deng
    posted to 20q aurka p53 by YuvalTabach on 2008-08-03 15:41:37 as **
  • Defective induction but normal activation and function of p53 in mouse cells lacking poly-ADP-ribose polymerase.
    Oncogene, Vol. 15, No. 9. (28 August 1997), pp. 1035-1041.
    by ML Agarwal, A Agarwal, WR Taylor, ZQ Wang, EF Wagner, GR Stark
    posted to p53 parpdeficiency by yedmonds on 2005-06-27 17:54:07 as ****
  • Roles of poly(ADP-ribosyl)ation and PARP in apoptosis, DNA repair, genomic stability and functions of p53 and E2F-1.
    Adv Enzyme Regul, Vol. 40 (2000), pp. 183-215.
    by ME Smulson, CM Simbulan-Rosenthal, AH Boulares, A Yakovlev, B Stoica, S Iyer, R Luo, B Haddad, ZQ Wang, T Pang, M Jung, A Dritschilo, DS Rosenthal
    posted to dnadamagerepair genomicstability p53 par parp by yedmonds on 2005-06-20 15:44:43 as ***
  • ATM-dependent telomere loss in aging human diploid fibroblasts and DNA damage lead to the post-translational activation of p53 protein involving poly(ADP-ribose) polymerase.
    EMBO J, Vol. 16, No. 19. (1 October 1997), pp. 6018-6033.
    by H Vaziri, MD West, RC Allsopp, TS Davison, YS Wu, CH Arrowsmith, GG Poirier, S Benchimol
    posted to ageing dnadamagerepair p53 parp telomeres by yedmonds on 2005-06-22 14:44:36 as read
  • Poly(ADP-ribose) polymerase-1 regulates the stability of the wild-type p53 protein.
    Cell Mol Biol Lett, Vol. 6, No. 2. (2001), pp. 117-140.
    by J Wesierska-Gadek, G Schmid
    posted to p53 parp by yedmonds on 2005-06-29 14:52:17 as ****
  • Regulation of p53 sequence-specific DNA-binding by covalent poly(ADP-ribosyl)ation.
    J Biol Chem, Vol. 276, No. 39. (28 September 2001), pp. 36425-36430.
    by H Mendoza-Alvarez, R Alvarez-Gonzalez
    posted to p53 par parp by yedmonds on 2005-06-22 14:59:59 as read
  • Central and carboxy-terminal regions of human p53 protein are essential for interaction and complex formation with PARP-1.
    J Cell Biochem, Vol. 89, No. 2. (15 May 2003), pp. 220-232.
    by J Wesierska-Gadek, J Wojciechowski, G Schmid
    posted to p53 parpbinding by yedmonds on 2005-07-08 16:44:52 as ***
  • Telomere shortening triggers a p53-dependent cell cycle arrest via accumulation of G-rich single stranded DNA fragments.
    Oncogene, Vol. 18, No. 37. (16 September 1999), pp. 5148-5158.
    by G Saretzki, N Sitte, U Merkel, RE Wurm, T von Zglinicki
    posted to ageing p53 telomeres by yedmonds on 2005-06-20 20:25:24 as **
  • Physiological ageing: role of p53 and PARP-1 tumor suppressors in the regulation of terminal senescence.
    J Physiol Pharmacol, Vol. 56 Suppl 2 (March 2005), pp. 77-88.
    by J Wesierska-Gadek, C Ranftler, G Schmid
    posted to ageing p53 parp senescence by yedmonds on 2005-08-11 15:01:50 as read
  • Poly(ADP-ribosyl)ation of p53 during apoptosis in human osteosarcoma cells.
    Cancer Res, Vol. 59, No. 9. (1 May 1999), pp. 2190-2194.
    by CM Simbulan-Rosenthal, DS Rosenthal, R Luo, ME Smulson
    posted to apoptosis p53 par by yedmonds on 2005-07-01 16:21:15 as read
  • hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase.
    Cell, Vol. 107, No. 2. (19 October 2001), pp. 149-159.
    by H Vaziri, SK Dessain, E Ng Eaton, SI Imai, RA Frye, TK Pandita, L Guarente, RA Weinberg
    posted to p53 sir2 by yedmonds on 2005-06-20 21:01:20 as **
  • Poly(ADP-ribose) binds to specific domains of p53 and alters its DNA binding functions.
    J Biol Chem, Vol. 273, No. 19. (8 May 1998), pp. 11839-11843.
    by M Malanga, JM Pleschke, HE Kleczkowska, FR Althaus
    posted to p53 par by yedmonds on 2005-06-20 15:27:32 as read
  • Advantage of a baculovirus expression system for protein-protein interaction studies. Involvement of posttranslational phosphorylation in the interaction between wt p53 protein and poly(ADP-ribose) polymerase-1.
    Acta Biochim Pol (4 August 2005)
    by Gerald Schmid, Jacek Wojciechowski, Józefa Węsierska-Gądek
    posted to p53 parp parpbinding by yedmonds on 2005-08-11 14:56:52 as *** along with 1 person ieken
  • Negative control of p53 by Sir2alpha promotes cell survival under stress.
    Cell, Vol. 107, No. 2. (19 October 2001), pp. 137-148.
    by J Luo, AY Nikolaev, S Imai, D Chen, F Su, A Shiloh, L Guarente, W Gu
    posted to ageing p53 sir2 by yedmonds on 2005-06-20 21:02:09 as ***
  • ADP-ribosylation of wild-type p53 in vitro: binding of p53 protein to specific p53 consensus sequence prevents its modification.
    Biochem Biophys Res Commun, Vol. 224, No. 1. (5 July 1996), pp. 96-102.
    by J Wesierska-Gadek, G Schmid, C Cerni
    posted to p53 par by yedmonds on 2005-06-22 14:43:25 as read
  • The role of poly(ADP-ribose) in the DNA damage signaling network.
    Biochem Cell Biol, Vol. 83, No. 3. (June 2005), pp. 354-364.
    by Maria Malanga, Felix R Althaus
    posted to dnadamagerepair p21 p53 par by yedmonds on 2005-06-29 15:00:12 as read
  • Prolongation of the p53 response to DNA strand breaks in cells depleted of PARP by antisense RNA expression.
    Biochem Biophys Res Commun, Vol. 253, No. 3. (30 December 1998), pp. 864-868.
    by CM Simbulan-Rosenthal, DS Rosenthal, R Ding, K Bhatia, ME Smulson
    posted to dnadamagerepair p53 parp by yedmonds on 2005-06-20 19:41:38 as ***
  • Poly(ADP-ribosyl)ation of p53 in vitro and in vivo modulates binding to its DNA consensus sequence.
    Neoplasia, Vol. 3, No. 3. (n 2001), pp. 179-188.
    by CM Simbulan-Rosenthal, DS Rosenthal, RB Luo, R Samara, M Jung, A Dritschilo, A Spoonde, ME Smulson
    posted to p53 parp by yedmonds on 2005-06-29 14:54:16 as read
  • Involvement of NAD-poly(ADP-ribose) metabolism in p53 regulation and its consequences.
    Cancer Res, Vol. 55, No. 17. (1 September 1995), pp. 3697-3701.
    by CM Whitacre, H Hashimoto, ML Tsai, S Chatterjee, SJ Berger, NA Berger
    posted to p53 par by yedmonds on 2005-06-27 17:40:57 as ****
  • Poly(ADP-ribosyl)ation is required for p53-dependent signal transduction induced by radiation.
    Oncogene, Vol. 17, No. 22. (3 December 1998), pp. 2819-2825.
    by X Wang, K Ohnishi, A Takahashi, T Ohnishi
    posted to dnadamagerepair p53 par by yedmonds on 2005-06-27 17:42:20 as ****
  • Poly(ADP-ribose) polymerase-1 is a positive regulator of the p53-mediated G1 arrest response following ionizing radiation.
    J Biol Chem, Vol. 278, No. 21. (23 May 2003), pp. 18914-18921.
    by S Wieler, JP Gagné, H Vaziri, GG Poirier, S Benchimol
    posted to p53 parp by yedmonds on 2005-06-20 14:54:19 as ***
  • Functional interactions of p53 with poly(ADP-ribose) polymerase (PARP) during apoptosis following DNA damage: covalent poly(ADP-ribosyl)ation of p53 by exogenous PARP and noncovalent binding of p53 to the M(r) 85,000 proteolytic fragment.
    Cancer Res, Vol. 58, No. 22. (15 November 1998), pp. 5075-5078.
    by SR Kumari, H Mendoza-Alvarez, R Alvarez-Gonzalez
    posted to dnadamagerepair p53 par parp by yedmonds on 2005-06-20 19:40:22 as ****
  • Phosphorylation regulates the interaction and complex formation between wt p53 protein and PARP-1.
    J Cell Biochem, Vol. 89, No. 6. (15 August 2003), pp. 1260-1284.
    by J Wesierska-Gadek, J Wojciechowski, G Schmid
    posted to p53 parpbinding by yedmonds on 2005-06-29 14:49:30 as read
  • p53 mutant mice that display early ageing-associated phenotypes.
    Nature, Vol. 415, No. 6867. (3 January 2002), pp. 45-53.
    by SD Tyner, S Venkatachalam, J Choi, S Jones, N Ghebranious, H Igelmann, X Lu, G Soron, B Cooper, C Brayton, S Hee Park, T Thompson, G Karsenty, A Bradley, LA Donehower
    posted to ageing p53 by yedmonds on 2005-06-20 21:04:29 as *
  • Reduced stability of regularly spliced but not alternatively spliced p53 protein in PARP-deficient mouse fibroblasts.
    Cancer Res, Vol. 59, No. 1. (1 January 1999), pp. 28-34.
    by J Wesierska-Gadek, ZQ Wang, G Schmid
    posted to p53 parpdeficiency by yedmonds on 2005-06-27 17:55:05 as ***
  • Targeting protein-protein interactions: Lessons from p53/MDM2.
    Biopolymers, Vol. 88, No. 5. (10 April 2007), pp. 657-686.
    by Justin K K Murray, Samuel H H Gellman
    posted to interaction mdm2 molecule p53 protein small by yeastyboy on 2007-09-11 12:32:46 as ** along with 2 people jyuh higueruelo
  • HDM2 antagonist Nutlin-3 disrupts p73-HDM2 binding and enhances p73 function
    Oncogene, Vol. aop, No. current.
    by LMS Lau, JK Nugent, X Zhao, MS Irwin
    posted to interaction mdm2 molecule nutlin p53 small by yeastyboy on 2007-09-11 12:21:23 as **
  • Small-molecule MDM2 antagonists reveal aberrant p53 signaling in cancer: implications for therapy.
    Proc Natl Acad Sci U S A, Vol. 103, No. 6. (7 February 2006), pp. 1888-1893.
    by C Tovar, J Rosinski, Z Filipovic, B Higgins, K Kolinsky, H Hilton, X Zhao, BT Vu, W Qing, K Packman, O Myklebost, DC Heimbrook, LT Vassilev
    posted to discovery drug interaction molecule nutlin p53 protein small by yeastyboy on 2007-09-16 14:08:35 as read along with 2 people sbiring Evangelia
  • Induction of p53-dependent senescence by the MDM2 antagonist nutlin-3a in mouse cells of fibroblast origin.
    Cancer Res, Vol. 67, No. 15. (1 August 2007), pp. 7350-7357.
    by A Efeyan, A Ortega-Molina, S Velasco-Miguel, D Herranz, LT Vassilev, M Serrano
    posted to interaction mdm2 molecule nutlin p53 small by yeastyboy on 2007-09-11 12:25:28 as **
  • Nutlin-3 inhibits the NFkappaB Pathway in a p53 Dependent Manner: Implications in Lung Cancer Therapy.
    Cell Cycle, Vol. 6, No. 17. (27 June 2007)
    by Anwesha Dey, E T T Wong, P Bist, V Tergaonkar, David P Lane
    posted to interaction mdm2 nutlin p53 by yeastyboy on 2007-09-11 12:18:27 as **
  • notes Gene-specific requirement for P-TEFb activity and RNA polymerase II phosphorylation within the p53 transcriptional program.
    Genes Dev, Vol. 20, No. 5. (1 March 2006), pp. 601-612.
    by NP Gomes, G Bjerke, B Llorente, SA Szostek, BM Emerson, JM Espinosa
    posted to gene-specific p-tefb p53 phosphorylation rnapii transcription by xico on 2006-04-04 19:02:52 as *** along with 1 group WetBiology
  • p53 in health and disease
    Nature Reviews Molecular Cell Biology, Vol. 8, No. 4., pp. 275-283.
    by Karen H Vousden, David P Lane
    posted to anti-oncogene apoptosis cancer cell cycle disease health oncogene p53 review by xico on 2007-03-24 21:08:35 as ** along with 3 people and 1 group jyuh cjeans lyndallsarkies WetBiology
  • Principles of tumor suppression.
    Cell, Vol. 116, No. 2. (23 January 2004), pp. 235-246.
    by CJ Sherr
    posted to cancer p53 rb review suppression suppressors tumor tumorigenesis by xico on 2006-02-16 19:57:36 as **** along with 2 people and 1 group Borelli gloria WetBiology
  • Conformationally altered p53: a novel Alzheimer's disease marker?
    Molecular Psychiatry, Vol. aop, No. current.
    by C Lanni, M Racchi, G Mazzini, A Ranzenigo, R Polotti, E Sinforiani, L Olivari, M Barcikowska, M Styczynska, J Kuznicki, A Szybinska, S Govoni, M Memo, D Uberti
    posted to alzheimers disease p53 test by willgiardino on 2008-05-19 17:59:22 as **
  • Perp-etrating p53-dependent apoptosis.
    Cell cycle (Georgetown, Tex.), Vol. 3, No. 3. (March 2004), pp. 267-269.
    by RA Ihrie, LD Attardi
    posted to apoptosis p53 perp by whitew0a on 2008-06-25 12:19:30 as **
  • Multiple response elements and differential p53 binding control Perp expression during apoptosis.
    Molecular cancer research : MCR, Vol. 1, No. 14. (December 2003), pp. 1048-1057.
    by EE Reczek, ER Flores, AS Tsay, LD Attardi, T Jacks
    posted to apoptosis p53 perp by whitew0a on 2008-06-25 12:19:52 as **
  • On the shoulders of giants: p63, p73 and the rise of p53
    Trends in Genetics, Vol. 18, No. 2. (1 February 2002), pp. 90-95.
    by Annie Yang, Mourad Kaghad, Daniel Caput, Frank Mckeon
    posted to p53 p63 p73 by viktor21614 on 2007-08-12 19:40:10 as **
  • From the Cover: Acrolein is a major cigarette-related lung cancer agent: Preferential binding at p53 mutational hotspots and inhibition of DNA repair
    PNAS, Vol. 103, No. 42. (17 October 2006), pp. 15404-15409.
    by Zhaohui Feng, Wenwei Hu, Yu Hu, Moon-Shong Tang
    posted to acrolein cigarette dna_repair lung_cancer mutation_hotspot p53 by uz_labu_laimi on 2007-03-30 05:14:47 as **
  • The attractive Achilles heel of germ cell tumours: an inherent sensitivity to apoptosis-inducing stimuli.
    J Pathol, Vol. 200, No. 2. (June 2003), pp. 137-148.
    by DC Spierings, EG de Vries, E Vellenga, S de Jong
    posted to apoptosis cisplatin male_germ_line mdm2 p53 testis tumour by uz_labu_laimi on 2007-08-28 16:02:53 as ** along with 1 person daed
  • hnRNP K: an HDM2 target and transcriptional coactivator of p53 in response to DNA damage.
    Cell, Vol. 123, No. 6. (16 December 2005), pp. 1065-1078.
    by A Moumen, P Masterson, MJ O'Connor, SP Jackson
    posted to dna_damage hdm2 hnrnp_k p53 by uz_labu_laimi on 2007-08-27 16:42:29 as ****
  • p53 targets identified by protein expression profiling.
    Proc Natl Acad Sci U S A, Vol. 104, No. 13. (27 March 2007), pp. 5401-5406.
    by R Rahman-Roblick, UJ Roblick, U Hellman, P Conrotto, T Liu, S Becker, D Hirschberg, H Jörnvall, G Auer, KG Wiman
    posted to cancer carcinoma colon_cancer hnrnp_k p53 protein_expression_profiling redox_regulation by uz_labu_laimi on 2007-04-25 20:00:34 as ** along with 1 person gedelb
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