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Tag p450 [75 articles]

Recent papers classified by the tag p450.
  • Prediction of binding modes for ligands in the cytochromes P450 and other heme-containing proteins
    Proteins: Structure, Function, and Bioinformatics, Vol. 58, No. 4. (2005), pp. 836-844.
    by Stewart B Kirton, Christopher W Murray, Marcel L Verdonk, Richard D Taylor
    posted to p450 by yongzhao on 2006-11-02 01:38:26 as *** along with 1 group TSRI_MGL
  • Designing better drugs: predicting cytochrome P450 metabolism
    Drug Discovery Today, Vol. 11, No. 13-14. (July 2006), pp. 601-606.
    by Marcel J de Groot
    posted to p450 by yongzhao on 2006-08-15 01:14:33 as ** along with 1 group TSRI_MGL
  • Prediction of Small-Molecule Binding to Cytochrome P450 3A4: Flexible Docking Combined with Multidimensional QSAR
    ChemMedChem, Vol. 1, No. 1. (2006), pp. 73-81.
    by Markus a, Max Dobler, Angelo Vedani
    posted to p450 by yongzhao on 2006-08-15 00:34:17 as **** along with 1 person and 1 group cen4ik TSRI_MGL
  • Cloning, functional expression, and characterization of CYP709C1, the first sub-terminal hydroxylase of long chain fatty acid in plants. Induction by chemicals and methyl jasmonate.
    J Biol Chem, Vol. 280, No. 43. (28 October 2005), pp. 35881-35889.
    by S Kandel, M Morant, I Benveniste, E Blée, D Werck-Reichhart, F Pinot
    posted to p450 safener by tkomives on 2006-12-26 11:03:52 as **
  • Evolution and function of the NR1I nuclear hormone receptor subfamily (VDR, PXR, and CAR) with respect to metabolism of xenobiotics and endogenous compounds.
    Current drug metabolism, Vol. 7, No. 4. (May 2006), pp. 349-365.
    by EJ Reschly, MD Krasowski
    posted to admet cytochrome induction p450 pxr by superpyrin on 2008-06-01 07:56:27 as **
  • Drugs behave as substrates, inhibitors and inducers of human cytochrome P450 3A4.
    Current drug metabolism, Vol. 9, No. 4. (May 2008), pp. 310-322.
    by SF Zhou
    posted to 3a4 cytochrome induction p450 by superpyrin on 2008-06-05 11:20:19 as **
  • Cytochrome p450 in silico: an integrative modeling approach.
    J Med Chem, Vol. 48, No. 8. (21 April 2005), pp. 2725-2755.
    by C de Graaf, NP Vermeulen, KA Feenstra
    posted to cytochrome p450 by superpyrin on 2007-07-17 13:18:46 as *** along with 1 person feenstra
  • PXR, CAR and drug metabolism.
    Nature reviews. Drug discovery, Vol. 1, No. 4. (April 2002), pp. 259-266.
    by TM Willson, SA Kliewer
    posted to induction p450 pxr by superpyrin on 2008-05-27 12:59:29 as **
  • The effect of cytochrome P450 metabolism on drug response, interactions, and adverse effects.
    Am Fam Physician, Vol. 76, No. 3. (1 August 2007), pp. 391-396.
    by T Lynch, A Price
    posted to 2d6 3a4 p450 by superpyrin on 2007-10-14 09:57:38 as ** along with 1 person guhjy
  • COMPARISON OF METHODS FOR THE PREDICTION OF THE METABOLIC SITES FOR CYP3A4-MEDIATED METABOLIC REACTIONS
    Drug Metab Dispos, Vol. 34, No. 6. (1 June 2006), pp. 976-983.
    by Diansong Zhou, Lovisa Afzelius, Scott W Grimm, Tommy B Andersson, Randy J Zauhar, Ismael Zamora
    posted to metasite p450 by superpyrin on 2008-04-01 13:47:05 as **
  • Summary of information on human CYP enzymes: human P450 metabolism data.
    Drug Metab Rev, Vol. 34, No. 1-2. (y 2002), pp. 83-448.
    by S Rendic
    posted to 2d6 3a4 p450 by superpyrin on 2007-10-14 09:49:08 as ** along with 1 person girschick
  • In Silico Prediction of Cytochrome P450 2D6 and 3A4 Inhibition Using Gaussian Kernel Weighted k-Nearest Neighbor and Extended Connectivity Fingerprints, Including Structural Fragment Analysis of Inhibitors versus Noninhibitors
    J. Med. Chem., Vol. 50, No. 3. (8 February 2007), pp. 501-511.
    by BF Jensen, C Vind, SB Padkjar, PB Brockhoff, HHF Refsgaard
    posted to 2d6 3a4 admet cytochrome p450 by superpyrin on 2008-06-19 14:38:30 as **
  • Regulation of P450 genes by liver-enriched transcription factors and nuclear receptors
    Biochimica et Biophysica Acta (BBA) - General Subjects, Vol. 1619, No. 3. (17 February 2003), pp. 223-234.
    by Taro E Akiyama, Frank J Gonzalez
    posted to induction p450 pxr by superpyrin on 2008-05-27 12:23:08 as **
  • An in silico analysis of cytochrome c from Phanerochaete chrysosporium: its amino acid sequence and characterization of gene structural elements.
    In silico biology, Vol. 8, No. 1. (2008), pp. 1-13.
    by JA Bumpus, M Trax, A Reisdorph, C Boyd, D Gilbert, S Techau, RM Ventullo
    posted to p450 phanerochaete phanerochaete_chrysosporium by stajich on 2008-07-28 06:19:23 as ** along with 1 group Berkeley Mycology
  • Fungal cytochrome P450 database
    BMC Genomics, Vol. 9 (28 August 2008), 402.
    by Jongsun Park, Seungmin Lee, Jaeyoung Choi, Kyohun Ahn, Bongsoo Park, Jaejin Park, Seogchan Kang, Yong-Hwan Lee
    posted to p450 fungi database cytochrome by stajich on 2008-10-05 22:41:29 as ** along with 1 group Berkeley Mycology
  • The Cytochrome P450 Lanosterol 14alpha-Demethylase Gene Is a Demethylation Inhibitor Fungicide Resistance Determinant in Monilinia fructicola Field Isolates from Georgia
    Appl. Environ. Microbiol., Vol. 74, No. 2. (15 January 2008), pp. 359-366.
    by Chao-Xi Luo, Guido Schnabel
    posted to ascomycota copy_number_variation fungi fungicide p450 resistance by stajich on 2008-01-09 23:14:53 as ** along with 1 group Berkeley Mycology
  • P450ome of the white rot fungus Phanerochaete chrysosporium: structure, evolution and regulation of expression of genomic P450 clusters.
    Biochem Soc Trans, Vol. 34, No. Pt 6. (December 2006), pp. 1165-1169.
    by JS Yadav, H Doddapaneni, V Subramanian
    posted to cytochrome p450 phanerochaete_chrysosporium by stajich on 2007-02-19 16:44:10 as ** along with 1 person GustavoLacerda
  • Evaluation of Different Virtual Screening Programs for Docking in a Charged Binding Pocket
    J. Chem. Inf. Model. (27 September 2008)
    by Wei Deng, Christophe L Verlinde
    posted to p450 glide fred dockingscoring docking chargedpocket by sschurer on 2008-10-17 22:54:52 as ** along with 1 person zimbo1
  • A novel sterol 14alpha-demethylase/ferredoxin fusion protein (MCCYP51FX) from Methylococcus capsulatus represents a new class of the cytochrome P450 superfamily.
    J Biol Chem, Vol. 277, No. 49. (6 December 2002), pp. 46959-46965.
    by CJ Jackson, DC Lamb, TH Marczylo, AG Warrilow, NJ Manning, DJ Lowe, DE Kelly, SL Kelly
    posted to p450 by robert on 2006-02-13 15:29:42 as **
  • Crystal structure of human cytochrome P450 2C9 with bound warfarin.
    Nature, Vol. 424, No. 6947. (24 July 2003), pp. 464-468.
    by PA Williams, J Cosme, A Ward, HC Angove, D Matak Vinković, H Jhoti
    posted to crystal-structure p450 by robert on 2006-02-10 09:57:10 as **
  • Models and mechanisms of O-O bond activation by cytochrome P450. A critical assessment of the potential role of multiple active intermediates in oxidative catalysis.
    Eur J Biochem, Vol. 271, No. 22. (November 2004), pp. 4335-4360.
    by P Hlavica
    posted to p450 review by robert on 2006-06-23 14:57:00 as **
  • Involvement of a cytochrome P450 monooxygenase in thaxtomin A biosynthesis by Streptomyces acidiscabies.
    J Bacteriol, Vol. 184, No. 7. (April 2002), pp. 2019-2029.
    by FG Healy, SB Krasnoff, M Wach, DM Gibson, R Loria
    posted to biosynthesis nitro-compounds p450 uv by robert on 2006-08-28 16:33:02 as **
  • Evolution of bioinorganic motifs in P450-containing systems.
    Biochem Soc Trans, Vol. 29, No. Pt 2. (May 2001), pp. 139-147.
    by KN Degtyarenko, TA Kulikova
    posted to oxygenases p450 review by robert on 2006-10-05 17:03:26 as **
  • Bacterial P450-catalyzed polyketide hydroxylation on a microfluidic platform.
    Biotechnol Bioeng, Vol. 88, No. 4. (20 November 2004), pp. 528-535.
    by A Srinivasan, H Bach, DH Sherman, JS Dordick
    posted to biocatalysis p450 by robert on 2006-02-27 10:10:04 as **
  • An A245T mutation conveys on cytochrome P450eryF the ability to oxidize alternative substrates.
    J Biol Chem, Vol. 275, No. 46. (17 November 2000), pp. 35999-36006.
    by H Xiang, RA Tschirret-Guth, PR Ortiz De Montellano
    posted to biocatalysis p450 structure-function by robert on 2006-02-13 15:48:18 as **
  • Stopped-flow kinetic studies of electron transfer in the reductase domain of neuronal nitric oxide synthase: re-evaluation of the kinetic mechanism reveals new enzyme intermediates and variation with cytochrome P450 reductase.
    Biochem J, Vol. 367, No. Pt 1. (1 October 2002), pp. 19-30.
    by K Knight, NS Scrutton
    posted to analysis electron-transfer flavin p450 by robert on 2006-02-27 09:38:28 as **
  • Microbial P450 enzymes in biotechnology.
    Appl Microbiol Biotechnol, Vol. 64, No. 3. (April 2004), pp. 317-325.
    by VB Urlacher, S Lutz-Wahl, RD Schmid
    posted to biocatalysis oxygenases p450 by robert on 2006-09-25 13:48:36 as ** along with 1 person richter80
  • Mechanism of oxidation reactions catalyzed by cytochrome p450 enzymes.
    Chem Rev, Vol. 104, No. 9. (September 2004), pp. 3947-3980.
    by B Meunier, SP de Visser, S Shaik
    posted to p450 review by robert on 2007-11-19 15:53:56 as **
  • Biotransformations using prokaryotic P450 monooxygenases.
    Curr Opin Biotechnol, Vol. 13, No. 6. (December 2002), pp. 557-564.
    by V Urlacher, RD Schmid
    posted to biocatalysis functional-analysis p450 by robert on 2006-02-27 10:01:18 as *****
  • Structural aspects of ligand binding to and electron transfer in bacterial and fungal P450s.
    Annu Rev Biochem, Vol. 73 (2004), pp. 991-1018.
    by O Pylypenko, I Schlichting
    posted to heme oxygenases p450 review by robert on 2006-02-24 10:50:34 as **
  • Enhanced heterologous expression of two Streptomyces griseolus cytochrome P450s and Streptomyces coelicolor ferredoxin reductase as potentially efficient hydroxylation catalysts.
    Appl Environ Microbiol, Vol. 69, No. 1. (January 2003), pp. 373-382.
    by HA Hussain, JM Ward
    posted to ecoli expression ferredoxin p450 streptomyces by robert on 2006-02-08 11:56:27 as **
  • Formation of the aureothin tetrahydrofuran ring by a bifunctional cytochrome P450 monooxygenase.
    J Am Chem Soc, Vol. 126, No. 51. (29 December 2004), pp. 16742-16743.
    by J He, M Müller, C Hertweck
    posted to aureothin p450 by robert on 2006-02-10 15:30:18 as ** along with 1 person manzanita
  • Photophysical properties of cytochromes c-553 and c3 extracted from Desulfovibrio vulgaris Miyazaki
    Journal of Photochemistry and Photobiology A: Chemistry, Vol. 120, No. 2. (18 January 1999), pp. 125-133.
    by Miriam Abe, Tatsuhiko Yagi, Hideyuki Itagaki, Toshihiko Nagamura
    posted to fluorescence heme heme-protein iron p450 reference uv by robert on 2006-10-13 12:46:21 as **
  • Role of the cytochrome P450 NocL in nocardicin A biosynthesis.
    J Am Chem Soc, Vol. 124, No. 28. (17 July 2002), pp. 8186-8187.
    by WL Kelly, CA Townsend
    posted to biosynthesis n-oxidation oxime p450 by robert on 2006-02-27 10:21:13 as **
  • P450 superfamily: update on new sequences, gene mapping, accession numbers and nomenclature.
    Pharmacogenetics, Vol. 6, No. 1. (February 1996), pp. 1-42.
    by DR Nelson, L Koymans, T Kamataki, JJ Stegeman, R Feyereisen, DJ Waxman, MR Waterman, O Gotoh, MJ Coon, RW Estabrook, IC Gunsalus, DW Nebert
    posted to p450 nomenclature by richter80 on 2008-10-17 08:44:06 as ***
  • Electron transport pathway for a Streptomyces cytochrome P450: cytochrome P450 105D5-catalyzed fatty acid hydroxylation in Streptomyces coelicolor A3(2).
    The Journal of biological chemistry, Vol. 282, No. 24. (15 June 2007), pp. 17486-17500.
    by YJ Chun, T Shimada, R Sanchez-Ponce, MV Martin, L Lei, B Zhao, SL Kelly, MR Waterman, DC Lamb, FP Guengerich
    posted to electron p450 streptomyces transport by richter80 on 2008-07-31 14:33:48 as read
  • Sequential asymmetric polyketide heterocyclization catalyzed by a single cytochrome P450 monooxygenase (AurH).
    Angewandte Chemie (International ed. in English), Vol. 47, No. 46. (2008), pp. 8872-8875.
    by ME Richter, N Traitcheva, U Knüpfer, C Hertweck
    posted to vitro sequential p450 hydroxylation furan aurh by richter80 on 2008-11-21 10:11:23 as read
  • Complex reactions catalyzed by cytochrome P450 enzymes.
    Biochimica et biophysica acta, Vol. 1770, No. 3. (March 2007), pp. 314-329.
    by EM Isin, FP Guengerich
    posted to p450 by richter80 on 2008-07-31 14:39:38 as **
  • Characterization of the macrolide P-450 hydroxylase from Streptomyces venezuelae which converts narbomycin to picromycin.
    Biochemistry, Vol. 37, No. 42. (20 October 1998), pp. 14937-14942.
    by MC Betlach, JT Kealey, GW Ashley, R McDaniel
    posted to p450 vitro by richter80 on 2008-07-15 12:37:37 as read
  • Mechanisms of cytochrome P450 substrate oxidation: MiniReview.
    Journal of biochemical and molecular toxicology, Vol. 21, No. 4. (2007), pp. 163-168.
    by FP Guengerich
    posted to mechanism p450 by richter80 on 2008-07-31 14:29:36 as **
  • Dissection of the late steps in aureothin biosynthesis.
    Chembiochem, Vol. 7, No. 1. (January 2006), pp. 37-39.
    by M Müller, J He, C Hertweck
    posted to p450 biosynthesis aureothin by richter80 on 2008-10-07 13:58:27 as read along with 2 people robert manzanita
  • Cloning, expression and characterisation of CYP102A7, a self-sufficient P450 monooxygenase from Bacillus licheniformis.
    Applied microbiology and biotechnology, Vol. 79, No. 6. (July 2008), pp. 931-940.
    by M Dietrich, S Eiben, C Asta, TA Do, J Pleiss, VB Urlacher
    posted to p450 vitro by richter80 on 2008-07-31 14:24:50 as **
  • Cytochrome p450 complement (CYPome) of the avermectin-producer Streptomyces avermitilis and comparison to that of Streptomyces coelicolor A3(2).
    Biochemical and biophysical research communications, Vol. 307, No. 3. (1 August 2003), pp. 610-619.
    by DC Lamb, H Ikeda, DR Nelson, J Ishikawa, T Skaug, C Jackson, S Omura, MR Waterman, SL Kelly
    posted to p450 evolution coelicolor avermititlis by richter80 on 2008-10-14 12:51:50 as *** along with 1 person OriginalLurch
  • The Cytochrome P450 Engineering Database: a navigation and prediction tool for the cytochrome P450 protein family.
    Bioinformatics, Vol. 23, No. 15. (1 August 2007), pp. 2015-2017.
    by M Fischer, M Knoll, D Sirim, F Wagner, S Funke, J Pleiss
    posted to bioinformatics classification p450 by richter80 on 2008-07-31 16:29:12 as read along with 1 person guhjy
  • Molecular approach to aquatic environmental bioreporting: differential response to environmental inducers of cytochrome P450 monooxygenase genes in the detritivorous subalpine planktonic Crustacea, <i>Daphnia pulex</i>
    Molecular Ecology, Vol. 12, No. 9. (2003), pp. 2473-2481.
    by P David, C Dauphin-Villemant, A Mesneau, JC Meyran
    posted to p450 daphnia bioreporting by orzenil on 2008-10-25 18:15:44 as **
  • notes Cytochrome P450 activity mirrors nitric oxide levels in postoperative sepsis: predictive indicators of lethal outcome.
    Surgery, Vol. 141, No. 3. (March 2007), pp. 376-384.
    by AR Novotny, K Emmanuel, S Maier, A Westerholt, H Weighardt, J Stadler, H Bartels, M Schwaiger, JR Siewert, B Holzmann, CD Heidecke
    posted to no p450 sepsis by Kyaita on 2007-05-26 06:35:27 as **
  • Inhibition of human liver cytochrome P450 by star fruit juice.
    J Pharm Pharm Sci, Vol. 10, No. 4. (2007), pp. 496-503.
    by JW Zhang, Y Liu, J Cheng, W Li, H Ma, HT Liu, J Sun, LM Wang, YQ He, Y Wang, ZT Wang, L Yang
    posted to cyp2a6 inhibit lasko p450 starfruit by jlasko on 2008-01-16 19:48:35 as **
  • Identification of CYP2B6 Sequence Variants by Use of Multiplex PCR with Allele-Specific Genotyping
    Clin Chem, Vol. 50, No. 8. (1 August 2004), pp. 1372-1377.
    by Robyn M Jacob, Elaine C Johnstone, Matt J Neville, Robert T Walton
    posted to alleles biology genotyping molecular multiplex p450 pcr snp by jbolmarcich on 2008-01-09 22:36:34 as read
  • De Novo Expression of Transfected Human Class 1 Aldehyde Dehydrogenase (ALDH) Causes Resistance to Oxazaphosphorine Anti-cancer Alkylating Agents in Hamster V79 Cell Lines
    J. Biol. Chem., Vol. 271, No. 20. (17 May 1996), pp. 11884-11890.
    by Kevin D Bunting, Alan J Townsend
    posted to aldh alternative cyclophosphamide metabolism p450 by jbolmarcich on 2008-01-09 23:23:47 as ***
  • A Major Role for CYP2A6 in Nicotine C-Oxidation by Human Liver Microsomes
    J Pharmacol Exp Ther, Vol. 282, No. 3. (1 September 1997), pp. 1608-1614.
    by ES Messina, RF Tyndale, EM Sellers
    posted to p450 by jbolmarcich on 2008-01-09 23:32:36 as *** along with 1 person heathermcclellan
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