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Tag lac [49 articles]

Recent papers classified by the tag lac.
  • In Silico Evolved lac Operons Exhibit Bistability for Artificial Inducers, but Not for Lactose
    Biophys. J., Vol. 91, No. 8. (15 October 2006), pp. 2833-2843.
    by MJA van Hoek, P Hogeweg
    posted to bistability lac operon by ner25 on 2006-12-17 21:06:00 as *** along with 2 people madhadron cjeans
  • Feedback regulation in the lactose operon: a mathematical modeling study and comparison with experimental data.
    Biophys J, Vol. 84, No. 5. (May 2003), pp. 2841-2851.
    by N Yildirim, MC Mackey
    posted to lac model by ner25 on 2006-12-17 21:44:58 as **
  • Dynamics and bistability in a reduced model of the lac operon.
    Chaos, Vol. 14, No. 2. (June 2004), pp. 279-292.
    by N Yildirim, M Santillan, D Horike, MC Mackey
    posted to bistability lac by ner25 on 2006-12-17 21:44:25 as read
  • Alternative designs for a genetic switch: Analysis of switching times using the piecewise power-law representation
    Mathematical Biosciences, Vol. 180, No. 1-2. ( 2002), pp. 237-253.
    by Michael A Savageau
    posted to bistability lac operon by ner25 on 2006-12-17 21:26:13 as ***
  • ENZYME INDUCTION AS AN ALL-OR-NONE PHENOMENON.
    Proc Natl Acad Sci U S A, Vol. 43, No. 7. (15 July 1957), pp. 553-566.
    by A Novick, M Weiner
    posted to bistability lac by ner25 on 2006-12-17 21:38:28 as read
  • Structure of the complex of lac repressor headpiece and an 11 base-pair half-operator determined by nuclear magnetic resonance spectroscopy and restrained molecular dynamics.
    J Mol Biol, Vol. 234, No. 2. (20 November 1993), pp. 446-462.
    by VP Chuprina, JA Rullmann, RM Lamerichs, JH van Boom, R Boelens, R Kaptein
    posted to add lac by lna on 2006-01-08 14:25:32 as **
  • A closer view of the conformation of the Lac repressor bound to operator
    Nat Struct Mol Biol, Vol. 7, No. 3. (March 2000), pp. 209-214.
    by Charles E Bell, Mitchell Lewis
    posted to add lac by lna on 2006-01-08 16:19:58 as ** along with 1 person jstajic
  • Allosteric transition pathways in the lactose repressor protein core domains: asymmetric motions in a homodimer.
    Protein Sci, Vol. 12, No. 11. (November 2003), pp. 2523-2541.
    by TC Flynn, L Swint-Kruse, Y Kong, C Booth, KS Matthews, J Ma
    posted to lac by lna on 2006-01-12 10:17:49 as ** along with 1 person ruvido
  • Lysine 84 is at the subunit interface of lac repressor protein.
    J Biol Chem, Vol. 268, No. 23. (15 August 1993), pp. 17613-17622.
    by WI Chang, JS Olson, KS Matthews
    posted to add lac by lna on 2006-01-12 10:10:29 as **
  • Toward an integrated model of protein-DNA recognition as inferred from NMR studies on the Lac repressor system.
    Chem Rev, Vol. 104, No. 8. (August 2004), pp. 3567-3586.
    by CG Kalodimos, R Boelens, R Kaptein
    posted to examples lac by lna on 2005-12-27 14:07:03 as ** along with 1 person balicea
  • Characterization of two mutant lactose repressor proteins containing single tryptophans.
    J Biol Chem, Vol. 265, No. 34. (5 December 1990), pp. 21061-21067.
    by JA Gardner, KS Matthews
    posted to add lac by lna on 2006-01-12 13:53:55 as **
  • Crystal structure of the lactose operon repressor and its complexes with DNA and inducer.
    Science, Vol. 271, No. 5253. (1 March 1996), pp. 1247-1254.
    by M Lewis, G Chang, NC Horton, MA Kercher, HC Pace, MA Schumacher, RG Brennan, P Lu
    posted to examples lac struktur by lna on 2005-10-17 15:22:09 as **
  • Lac repressor genetic map in real space.
    Trends Biochem Sci, Vol. 22, No. 9. (September 1997), pp. 334-339.
    by HC Pace, MA Kercher, P Lu, P Markiewicz, JH Miller, G Chang, M Lewis
    posted to lac by lna on 2006-01-13 13:06:07 as ** along with 1 person jstajic
  • Lactose repressor protein: functional properties and structure.
    Prog Nucleic Acid Res Mol Biol, Vol. 58 (1998), pp. 127-164.
    by KS Matthews, JC Nichols
    posted to lac search by lna on 2006-01-08 13:11:54 as **
  • Refined structure of lac repressor headpiece (1-56) determined by relaxation matrix calculations from 2D and 3D NOE data: change of tertiary structure upon binding to the lac operator.
    J Mol Biol, Vol. 259, No. 4. (21 June 1996), pp. 761-773.
    by M Slijper, AM Bonvin, R Boelens, R Kaptein
    posted to add lac by lna on 2006-01-08 14:26:12 as **
  • A residue-specific view of the association and dissociation pathway in protein--DNA recognition.
    Nat Struct Biol, Vol. 9, No. 3. (March 2002), pp. 193-197.
    by CG Kalodimos, R Boelens, R Kaptein
    posted to examples lac by lna on 2005-06-06 16:33:15 as **
  • notes Genetic studies of the lac repressor. XIV. Analysis of 4000 altered Escherichia coli lac repressors reveals essential and non-essential residues, as well as "spacers" which do not require a specific sequence.
    J Mol Biol, Vol. 240, No. 5. (29 July 1994), pp. 421-433.
    by P Markiewicz, LG Kleina, C Cruz, S Ehret, JH Miller
    posted to lac search by lna on 2006-01-08 14:43:00 as **
  • Structure and flexibility adaptation in nonspecific and specific protein-DNA complexes.
    Science, Vol. 305, No. 5682. (16 July 2004), pp. 386-389.
    by CG Kalodimos, N Biris, AM Bonvin, MM Levandoski, M Guennuegues, R Boelens, R Kaptein
    posted to examples lac by lna on 2005-07-04 10:15:20 as ** along with 1 person jstajic
  • Prokaryotic transcription regulators: more than just the helix-turn-helix motif.
    Curr Opin Struct Biol, Vol. 12, No. 1. (February 2002), pp. 98-106.
    by JL Huffman, RG Brennan
    posted to examples lac by lna on 2005-12-27 14:10:26 as **
  • Combinatorial mutations of lac repressor. Stability of monomer-monomer interface is increased by apolar substitution at position 84.
    J Biol Chem, Vol. 272, No. 30. (25 July 1997), pp. 18550-18557.
    by JC Nichols, KS Matthews
    posted to add lac by lna on 2006-01-12 10:12:35 as **
  • The Lac repressor: a second generation of structural and functional studies.
    Curr Opin Struct Biol, Vol. 11, No. 1. (February 2001), pp. 19-25.
    by CE Bell, M Lewis
    posted to examples lac by lna on 2005-09-09 13:14:29 as **
  • Perturbation from a distance: mutations that alter LacI function through long-range effects.
    Biochemistry, Vol. 42, No. 47. (2 December 2003), pp. 14004-14016.
    by L Swint-Kruse, H Zhan, BM Fairbanks, A Maheshwari, KS Matthews
    posted to lac by lna on 2006-01-12 14:05:29 as **
  • Substitutions at histidine 74 and aspartate 278 alter ligand binding and allostery in lactose repressor protein.
    Biochemistry, Vol. 38, No. 12. (23 March 1999), pp. 3579-3590.
    by JK Barry, KS Matthews
    posted to add lac by lna on 2006-01-12 12:16:24 as **
  • Crystal structure of lac repressor core tetramer and its implications for DNA looping.
    Science, Vol. 268, No. 5218. (23 June 1995), pp. 1721-1727.
    by AM Friedman, TO Fischmann, TA Steitz
    posted to examples lac struktur by lna on 2005-10-17 15:21:28 as **
  • Role of Asp274 in lac repressor: diminished sugar binding and altered conformational effects in mutants.
    Biochemistry, Vol. 34, No. 28. (18 July 1995), pp. 9227-9234.
    by WI Chang, KS Matthews
    posted to add lac by lna on 2006-01-12 13:07:49 as **
  • Integrated insights from simulation, experiment, and mutational analysis yield new details of LacI function.
    Biochemistry, Vol. 44, No. 33. (23 August 2005), pp. 11201-11213.
    by L Swint-Kruse, H Zhan, KS Matthews
    posted to examples lac by lna on 2005-12-27 14:08:50 as **
  • Using networks to identify fine structural differences between functionally distinct protein states.
    Biochemistry, Vol. 43, No. 34. (31 August 2004), pp. 10886-10895.
    by L Swint-Kruse
    posted to lac by lna on 2006-01-12 09:30:09 as **
  • Designed disulfide between N-terminal domains of lactose repressor disrupts allosteric linkage.
    J Biol Chem, Vol. 272, No. 43. (24 October 1997), pp. 26818-26821.
    by CM Falcon, L Swint-Kruse, KS Matthews
    posted to add lac by lna on 2006-01-08 14:44:21 as **
  • Arginine 197 of lac repressor contributes significant energy to inducer binding. Confirmation of homology to periplasmic sugar binding proteins.
    J Biol Chem, Vol. 266, No. 34. (5 December 1991), pp. 22998-23002.
    by RO Spotts, AE Chakerian, KS Matthews
    posted to add lac by lna on 2006-01-12 14:00:49 as **
  • Strong DNA binding by covalently linked dimeric Lac headpiece: evidence for the crucial role of the hinge helices.
    Proc Natl Acad Sci U S A, Vol. 98, No. 11. (22 May 2001), pp. 6039-6044.
    by CG Kalodimos, GE Folkers, R Boelens, R Kaptein
    posted to examples lac by lna on 2005-07-13 11:03:16 as **
  • A mutant lactose repressor with altered inducer and operator binding parameters.
    J Mol Biol, Vol. 183, No. 1. (5 May 1985), pp. 43-51.
    by AE Chakerian, M Pfahl, JS Olson, KS Matthews
    posted to add lac by lna on 2006-01-12 12:11:25 as **
  • Formation of the hinge helix in the lac repressor is induced upon binding to the lac operator.
    Nat Struct Biol, Vol. 3, No. 11. (November 1996), pp. 916-919.
    by CA Spronk, M Slijper, JH van Boom, R Kaptein, R Boelens
    posted to add lac by lna on 2006-01-08 14:27:12 as **
  • Identification and characterization of aspartate residues that play key roles in the allosteric regulation of a transcription factor: aspartate 274 is essential for inducer binding in lac repressor.
    Biochemistry, Vol. 33, No. 12. (29 March 1994), pp. 3607-3616.
    by WI Chang, P Barrera, KS Matthews
    posted to add lac by lna on 2006-01-12 12:43:23 as **
  • Comparison of the E. coli lac repressor and its tryptic core by hydrogen exchange studies. Effect of inducer binding.
    Biochem Biophys Res Commun, Vol. 88, No. 1. (14 May 1979), pp. 124-129.
    by J Ramstein, M Charlier, JC Maurizot, AG Szabo, C Hélène
    posted to lac search by lna on 2006-01-09 08:54:27 as *****
  • Mechanism responsible for glucose-lactose diauxie in Escherichia coli: challenge to the cAMP model.
    Genes Cells, Vol. 1, No. 3. (March 1996), pp. 293-301.
    by T Inada, K Kimata, H Aiba
    posted to lac by jstajic on 2005-08-03 01:30:26 as ***
  • Detailed map of a cis-regulatory input function.
    Proc Natl Acad Sci U S A, Vol. 100, No. 13. (24 June 2003), pp. 7702-7707.
    by Y Setty, AE Mayo, MG Surette, U Alon
    posted to lac by jstajic on 2005-07-26 19:50:52 as *** along with 3 people comb discreteonyxorb madhadron
  • Modeling network dynamics: the lac operon, a case study.
    J Cell Biol, Vol. 161, No. 3. (12 May 2003), pp. 471-476.
    by JM Vilar, CC Guet, S Leibler
    posted to lac by jstajic on 2005-08-03 23:29:17 as read along with 7 people and 2 groups rklancer jjray bayesian balicea johncumbers wilsoros carmaus dIEMoSIRIS MoSi-Rostock
  • Interaction of divalent cations with beta-galactosidase (Escherichia coli).
    Biochemistry, Vol. 18, No. 19. (18 September 1979), pp. 4090-4095.
    by RE Huber, C Parfett, H Woulfe-Flanagan, DJ Thompson
    posted to lac by jstajic on 2005-07-29 01:06:14 as read
  • Stochastic Modeling and Control of Biological Systems: The Lactose Regulation System of Escherichia Coli
    Automatic Control, IEEE Transactions on, Vol. 53, No. Special Issue. (January 2008), pp. 51-65.
    by AA Julius, A Halasz, MS Sakar, H Rubin, V Kumar, GJ Pappas
    posted to bistable control ecoli lac operon stochastic by jporternj on 2008-06-18 20:25:26 as ***
  • Multistability in the lactose utilization network of Escherichia coli.
    Nature, Vol. 427, No. 6976. (19 February 2004), pp. 737-740.
    by EM Ozbudak, M Thattai, HN Lim, BI Shraiman, A Van Oudenaarden
    posted to bistable diagram lac operon phase by jporternj on 2008-06-17 21:05:32 as ** along with 5 people rklancer monod Norlins ner25 madhadron
  • Screening of peptide libraries linked to lac repressor.
    Methods Enzymol, Vol. 267 (1996), pp. 171-191.
    by PJ Schatz, MG Cull, EL Martin, CM Gates
    posted to lac minigene peptide peptide-on-plasmid random repressor by jddowney on 2007-09-26 18:55:21 as read
  • Optimality and evolutionary tuning of the expression level of a protein
    Nature, Vol. 436, No. 7050., pp. 588-592.
    by Erez Dekel, Uri Alon
    posted to evolution lac optimality by guyshinar on 2006-04-01 11:22:33 as read along with 4 people rklancer comb marcio michaelbarton
  • Transcriptional regulation by the numbers: models.
    Curr Opin Genet Dev, Vol. 15, No. 2. (April 2005), pp. 116-124.
    by L Bintu, NE Buchler, HG Garcia, U Gerland, T Hwa, J Kondev, R Phillips
    posted to bacteria combinatorial lac model theory transcription by discreteonyxorb on 2007-04-01 00:58:53 as ***** along with 4 people imouthesmp madhadron dquest ihpark
  • Transcriptional regulation by the numbers: applications.
    Curr Opin Genet Dev, Vol. 15, No. 2. (April 2005), pp. 125-135.
    by L Bintu, NE Buchler, HG Garcia, U Gerland, T Hwa, J Kondev, T Kuhlman, R Phillips
    posted to bacteria combinatorial lac model promoter theory transcription by discreteonyxorb on 2007-04-01 00:59:33 as ***** along with 5 people and 1 group imouthesmp dpollard madhadron dquest ihpark EisenLab
  • Programming gene expression with combinatorial promoters
    Mol Syst Biol, Vol. 3 (13 November 2007)
    by Robert S Cox, Michael G Surette, Michael B Elowitz
    posted to activation activator arabinose arac architecture bacteria bioinformatics biology circuits coli combinatorial comparative experimental factor gene initiation interaction lac laci library logic luciferase model noncoding operator organization polymerase prokaryote promoter protein regulation repression repressor sequence synthetic transcription by discreteonyxorb on 2007-11-13 20:48:20 as ***** along with 14 people and 2 groups Retchless tmmurali austin dpollard balicea kengg dbikard margaritis lusk cjeans zwang cabbagezs Ema tresch EisenLab SynBioSys
  • Mechanism and control of transcription initiation in prokaryotes.
    Annu Rev Biochem, Vol. 54 (1985), pp. 171-204.
    by WR McClure
    posted to activation architecture bacteria bioinformatics combinatorial initiation lac polymerase promoter regulation repression sequence transcription by discreteonyxorb on 2007-05-04 19:19:17 as *****
  • Plasticity of the cis-Regulatory Input Function of a Gene.
    PLoS Biol, Vol. 4, No. 4. (April 2006)
    by AE Mayo, Y Setty, S Shavit, A Zaslaver, U Alon
    posted to combinatorial crp directed evolution lac library logic mutagenesis promoter transcription by discreteonyxorb on 2007-04-04 21:13:32 as read along with 4 people and 1 group rklancer stevanspringer tmmurali bayesian FAB-lab
  • notes Evolving responsively: adaptive mutation.
    Nat Rev Genet, Vol. 2, No. 7. (July 2001), pp. 504-515.
    by SM Rosenberg
    posted to adaptation double_strand_break evolution evolvability lac mutation_rate poliv replication sos transletion by cambray on 2008-06-11 08:23:12 as read along with 8 people and 4 groups rklancer dayjm bala livingthingdan christiw grisogono rebeccamancy suizan DSTO-CAS DictyosteliumGroup livingthing ColDyn
  • Revised classification criteria for antiphospholipid syndrome and the thrombotic risk in patients with autoimmune diseases
    Journal of Thrombosis and Haemostasis, Vol. 5, No. 9. (September 2007), pp. 1883-1889.
    by J Swadzba, T Iwaniec, A Szczeklik, J Musial
    posted to acl antiphospholipid beta-2-glycoprotein classification criteria lac risk syndrome thrombotic by A_Hoogendam on 2007-12-19 13:40:31 as **
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