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Tag knockout [116 articles]

Recent papers classified by the tag knockout.
  • Phenotypic screening of hepatocyte nuclear factor (HNF) 4-gamma receptor knockout mice.
    Biochem Biophys Res Commun, Vol. 349, No. 2. (20 October 2006), pp. 825-832.
    by AK Gerdin, VV Surve, M Jönsson, M Bjursell, M Björkman, A Edenro, M Schuelke, A Saad, S Bjurström, EJ Lundgren, M Snaith, R Fransson-Steen, J Törnell, AL Berg, M Bohlooly-Y
    posted to expression hnf4gamma knockout by yevishere on 2008-01-03 23:33:55 as **
  • [Expressions of atherosclerosis-related genes in aorta in young apoE/LDLR double knockout mice.]
    Sheng Li Xue Bao, Vol. 60, No. 1. (25 February 2008), pp. 43-50.
    by XD Dai, M Yin, W Jing, HQ DU, HY Ye, YJ Shang, L Zhang, YY Zou, ZP Qu, J Pan
    posted to atherosclerosis knockout by YamaPing on 2008-02-23 05:14:21 as **
  • Global synthetic-lethality analysis and yeast functional profiling.
    Trends Genet, Vol. 22, No. 1. (January 2006), pp. 56-63.
    by SL Ooi, X Pan, BD Peyser, P Ye, PB Meluh, DS Yuan, RA Irizarry, JS Bader, FA Spencer, JD Boeke
    posted to functional global interaction knockout micro-array profiling review synthetic-lethal yeast yfg by xico on 2006-03-19 19:04:26 as **** along with 2 people and 2 groups nirfriedman nickluscombe WetBiology EBI-regulation
  • Epilepsy in Dcx Knockout Mice Associated with Discrete Lamination Defects and Enhanced Excitability in the Hippocampus
    PLoS ONE, Vol. 3, No. 6. (25 June 2008), e2473.
    by Marika Nosten-Bertrand, Caroline Kappeler, Céline Dinocourt, Cécile Denis, Johanne Germain, Dinh, Soraya Verstraeten, Chantal Alvarez, Christine Métin, Jamel Chelly, Bruno Giros, Richard Miles, Antoine Depaulis, Fiona Francis
    posted to ca3 doublecortin eeg epilepsy knockout lamination by TJ80 on 2008-06-30 16:53:00 as **
  • Gene expression profiles in a transgenic animal model of fragile X syndrome.
    Neurobiol Dis, Vol. 10, No. 3. (August 2002), pp. 211-218.
    by V D'Agata, ST Warren, W Zhao, ER Torre, DL Alkon, S Cavallaro
    posted to fmr1 genetique knockout ko by textoris on 2006-01-25 10:07:17 as read along with 1 person and 1 group jeremymiller GeschwindLab
  • Fmr1 knockout mice: a model to study fragile X mental retardation. The Dutch-Belgian Fragile X Consortium.
    Cell, Vol. 78, No. 1. (15 July 1994), pp. 23-33.
    posted to fmr1 genetique knockout ko by textoris on 2006-01-25 10:06:11 as read
  • CA3 NMDA receptors are crucial for rapid and automatic representation of context memory
    European Journal of Neuroscience, Vol. 24, No. 6. (September 2006), pp. 1771-1780.
    by Cravens, J Catherine, Vargas-Pinto, Noelia, Christian, M Kimberly, Nakazawa, Kazu
    posted to ca3 context knockout mice nmda by syngnarattus on 2007-02-14 21:34:32 as **
  • Rap1a Null Mice Have Altered Myeloid Cell Functions Suggesting Distinct Roles for the Closely Related Rap1a and 1b Proteins
    J Immunol, Vol. 179, No. 12. (15 December 2007), pp. 8322-8331.
    by Yu Li, Jingliang Yan, Pradip De, Hua-Chen Chang, Akira Yamauchi, Kent W Christopherson, Nivanka C Paranavitana, Xiaodong Peng, Chaekyun Kim, Veerendra Munugulavadla, Reuben Kapur, Hanying Chen, Weinian Shou, James C Stone, Mark H Kaplan, Mary C Dinauer, Donald L Durden, Lawrence A Quilliam
    posted to knockout rap1 by shimi002 on 2007-12-03 19:17:38 as **
  • Rap1b is required for normal platelet function and hemostasis in mice.
    The Journal of clinical investigation, Vol. 115, No. 3. (March 2005), pp. 680-687.
    by M Chrzanowska-Wodnicka, SS Smyth, SM Schoenwaelder, TH Fischer, GC White
    posted to knockout platelet rap1 by shimi002 on 2008-08-05 17:23:31 as **
  • Leukocytosis and resistance to septic shock in intercellular adhesion molecule 1-deficient mice.
    J Exp Med, Vol. 180, No. 1. (1 July 1994), pp. 95-109.
    by H Xu, JA Gonzalo, Y St Pierre, IR Williams, TS Kupper, RS Cotran, TA Springer, JC Gutierrez-Ramos
    posted to icam knockout by shimi002 on 2006-09-26 22:53:47 as ***
  • A Crucial Role for the p110delta Subunit of Phosphatidylinositol 3-Kinase in B Cell Development and Activation
    J. Exp. Med., Vol. 196, No. 6. (16 September 2002), pp. 753-763.
    by Elizabeth Clayton, Giuseppe Bardi, Sarah E Bell, David Chantry, Peter C Downes, Alexander Gray, Lisa A Humphries, David Rawlings, Helen Reynolds, Elena Vigorito, Martin Turner
    posted to knockout p110delta by shimi002 on 2007-12-26 21:32:07 as **
  • Deletion of alpha4 Integrins from Adult Hematopoietic Cells Reveals Roles in Homeostasis, Regeneration, and Homing
    Mol. Cell. Biol., Vol. 23, No. 24. (15 December 2003), pp. 9349-9360.
    by Linda M Scott, Gregory V Priestley, Thalia Papayannopoulou
    posted to integrin knockout vla-4 by shimi002 on 2007-05-02 15:40:59 as **
  • T Cell Responses in Mammalian Diaphanous-related Formin mDia1 Knock-out Mice
    J. Biol. Chem., Vol. 282, No. 34. (24 August 2007), pp. 25152-25158.
    by Kathryn M Eisenmann, Richard A West, Dagmar Hildebrand, Susan M Kitchen, Jun Peng, Robert Sigler, Jinyi Zhang, Katherine A Siminovitch, Arthur S Alberts
    posted to actin formin knockout by shimi002 on 2007-08-17 21:50:03 as **
  • Simple one-week method to construct gene-targeting vectors: application to production of human knockout cell lines.
    Biotechniques, Vol. 41, No. 3. (September 2006), pp. 311-316.
    by S Iiizumi, Y Nomura, S So, K Uegaki, K Aoki, K Shibahara, N Adachi, H Koyama
    posted to knockout method by shimi002 on 2006-12-28 17:12:50 as *** along with 2 people jyuh yeastyboy
  • p53 regulates glucose metabolism through an IKK-NF-κB pathway and inhibits cell transformation
    Nature Cell Biology, Vol. 10, No. 5. (06 April 2008), pp. 611-618.
    by Keiko Kawauchi, Keigo Araki, Kei Tobiume, Nobuyuki Tanaka
    posted to type tumor transporter transformation transduction transcription suppressor signal rna rela ras proteins protein physiology p53 neoplastic mice metabolism lactic knockout kinase interference i-kappa glycolysis glucose genetics genes fibroblasts factor cytology cultured cells cell b acid 3 by RubenE on 2008-09-15 13:50:15 as ***** along with 1 group CRI Cellular metabolism club
  • PPAR gamma is required for placental, cardiac, and adipose tissue development.
    Mol Cell, Vol. 4, No. 4. (October 1999), pp. 585-595.
    by Y Barak, MC Nelson, ES Ong, YZ Jones, P Ruiz-Lozano, KR Chien, A Koder, RM Evans
    posted to knockout ppargamma by qazwsx on 2005-05-29 12:54:23 as **
  • Extracting expression modules from perturbational gene expression compendia
    BMC Systems Biology, Vol. 2, No. 1. (2008)
    by Steven Maere, Patrick Van Dijck, Martin Kuiper
    posted to compendium emiel knockout module perturbation by ptrobajo on 2008-06-05 13:49:21 as ** along with 3 people jfr lp2 barriot
  • Experimental design for efficient identification of gene regulatory networks using sparse Bayesian models
    BMC Systems Biology, Vol. 1, No. 1. (2007)
    by Florian Steinke, Matthias Seeger, Koji Tsuda
    posted to bayesian design dragan experiment knockout network reconstruction by ptrobajo on 2008-07-31 15:59:55 as **
  • Exploiting the pathway structure of metabolism to reveal high-order epistasis.
    BMC systems biology, Vol. 2 (2008)
    by M Imielinski, C Belta
    posted to pathways metabolism knockout epistasis by ptrobajo on 2008-06-18 12:35:46 as ** along with 1 person jyuh
  • Building and analysing genome-wide gene disruption networks.
    Bioinformatics (Oxford, England), Vol. 18 Suppl 2 (2002)
    by J Rung, T Schlitt, A Brazma, K Freivalds, J Vilo
    posted to dragan emiel inference knockout network perturbation by ptrobajo on 2008-06-18 10:35:44 as **
  • Computing Knock-Out Strategies in Metabolic Networks
    Journal of Computational Biology, Vol. 15, No. 3. (2008), pp. 259-268.
    by Utz-Uwe Haus, Steffen Klamt, Tamon Stephen
    posted to dragan elementary knockout metabolic mode network by ptrobajo on 2008-03-31 19:36:49 as ** along with 5 people and 1 group tmmurali balicea jiny Borelli longoka Frontiers in Diabetes and Obesity
  • Using the topology of metabolic networks to predict viability of mutant strains.
    Biophys J, Vol. 91, No. 6. (September 2006), pp. 2304-2311.
    by Z Wunderlich, LA Mirny
    posted to dragan knockout metabolic miranda mutant network topology by ptrobajo on 2008-07-30 10:54:50 as ** along with 2 people kentsis cckan
  • A Bayesian regression approach to the inference of regulatory networks from gene expression data
    Bioinformatics, Vol. 21, No. 14. (15 July 2005), pp. 3131-3137.
    by Simon Rogers, Mark Girolami
    posted to bayesian dragan knockout network reconstruction regression by ptrobajo on 2008-07-31 15:49:58 as ** along with 1 person tvdbulck
  • Reconstructing gene-regulatory networks from time series, knock-out data, and prior knowledge
    BMC Systems Biology, Vol. 1, No. 1. (2007)
    by Florian Geier, Jens Timmer, Christian Fleck
    posted to bayesian dragan knockout network reconstruction series time by ptrobajo on 2008-07-31 15:53:18 as ** along with 5 people edwardmorrissey jyuh tuck wnpx Ao_Li2007
  • A critical role for interleukin-6 family-mediated Stat3 activation in osteoblast differentiation and bone formation.
    Bone, Vol. 39, No. 3. (September 2006), pp. 505-512.
    by S Itoh, N Udagawa, N Takahashi, F Yoshitake, H Narita, S Ebisu, K Ishihara
    posted to bone cre knockout osteoblast by pilumpyphi on 2006-11-13 20:47:29 as **
  • Development of mice with osteoblast-specific connexin43 gene deletion.
    Cell Commun Adhes, Vol. 10, No. 4-6. (c 2003), pp. 445-450.
    by CH Castro, JP Stains, S Sheikh, VL Szejnfeld, K Willecke, M Theis, R Civitelli
    posted to bone cre knockout osteoblast by pilumpyphi on 2006-11-13 21:07:54 as read
  • Targeting mammary epithelial cells using a bacterial artificial chromosome
    genesis, Vol. 33, No. 3. (2002), pp. 125-130.
    by Tim M Wintermantel, Anja K Mayer, Günther Schütz, Erich F Greiner
    posted to knockout socs3 wapicre by Piggeldi on 2008-07-29 09:30:02 as **
  • SOCS3 negatively regulates IL-6 signaling in vivo
    Nat Immunol, Vol. 4, No. 6. (June 2003), pp. 540-545.
    by Ben A Croker, Danielle L Krebs, Jian-Guo Zhang, Sam Wormald, Tracy A Willson, Edouard G Stanley, Lorraine Robb, Christopher J Greenhalgh, Irmgard Forster, Bjorn E Clausen, Nicos A Nicola, Donald Metcalf, Douglas J Hilton, Andrew W Roberts, Warren S Alexander
    posted to knockout socs3 by Piggeldi on 2008-07-29 10:15:17 as **
  • Mouse Models of Prostate Adenocarcinoma with the Capacity to Monitor Spontaneous Carcinogenesis by Bioluminescence or Fluorescence
    Cancer Res, Vol. 67, No. 15. (1 August 2007), pp. 7525-7533.
    by Chun-Peng Liao, Chen Zhong, Gohar Saribekyan, James Bading, Ryan Park, Peter S Conti, Rex Moats, Anton Berns, Wei Shi, Zongxiang Zhou, Alexander Y Nikitin, Pradip Roy-Burman
    posted to knockout pten by Piggeldi on 2008-07-29 10:48:55 as **
  • Altered Behavioral Responses to Noxious Stimuli and Fear in Glutamate Receptor 5 (GluR5)- or GluR6-Deficient Mice
    J. Neurosci., Vol. 25, No. 4. (26 January 2005), pp. 977-984.
    by Shanelle Ko, Ming-Gao Zhao, Hiroki Toyoda, Chang-Shen Qiu, Min Zhuo
    posted to aversive conditioning kainate knockout by nelmor on 2006-10-18 14:28:32 as **
  • Behavioral Phenotyping Strategies for Mutant Mice
    Neuron, Vol. 57, No. 6. (27 March 2008), pp. 809-818.
    by Jacqueline N Crawley
    posted to knockout methods mice by nelmor on 2008-03-27 11:46:39 as **
  • Dentate Gyrus NMDA Receptors Mediate Rapid Pattern Separation in the Hippocampal Network
    Science (7 June 2007), 1140263.
    by Thomas J Mchugh, Matthew W Jones, Jennifer J Quinn, Nina Balthasar, Roberto Coppari, Joel K Elmquist, Bradford B Lowell, Michael S Fanselow, Matthew A Wilson, Susumu Tonegawa
    posted to dentate extracellular-recordings hippocampus knockout learning mice nmda by nelmor on 2007-07-09 10:22:41 as ** along with 4 people and 1 group pgastrein shivakmr cannon nishiokov VisionLab
  • Distinct Subunits in Heteromeric Kainate Receptors Mediate Ionotropic and Metabotropic Function at Hippocampal Mossy Fiber Synapses
    J. Neurosci., Vol. 25, No. 50. (14 December 2005), pp. 11710-11718.
    by Arnaud Ruiz, Shankar Sachidhanandam, Jo K Utvik, Francoise Coussen, Christophe Mulle
    posted to kainate knockout mice sahp by nelmor on 2006-10-18 13:30:31 as **
  • Distinct Roles for the Kainate Receptor Subunits GluR5 and GluR6 in Kainate-Induced Hippocampal Gamma Oscillations
    J. Neurosci., Vol. 24, No. 43. (27 October 2004), pp. 9658-9668.
    by Andre Fisahn, Anis Contractor, Roger D Traub, Eberhard H Buhl, Stephen F Heinemann, Chris J Mcbain
    posted to epilepsy hippocampus kainate knockout mice oscillations by nelmor on 2006-10-18 13:20:16 as ** along with 1 person batallah
  • Mediator protein mutations that selectively abolish activated transcription
    Proceedings of the National Academy of Sciences, Vol. 96, No. 1. (5 January 1999), pp. 67-72.
    by Lawrence C Myers, Claes M Gustafsson, Kathleen C Hayashibara, Patrick O Brown, Roger D Kornberg
    posted to vp16 mediator med7 med4 med2 mapplab-classic knockout gcn4 by mapplab on 2008-09-19 20:57:35 as ** along with 1 person shuzhens
  • Global Mapping of the Yeast Genetic Interaction Network
    Science, Vol. 303, No. 5659. (06 February 2004), pp. 808-813.
    by Amy HY Tong, Guillaume Lesage, Gary D Bader, Huiming Ding, Hong Xu, Xiaofeng Xin, James Young, Gabriel F Berriz, Renee L Brost, Michael Chang, Yiqun Chen, Xin Cheng, Gordon Chua, Helena Friesen, Debra S Goldberg, Jennifer Haynes, Christine Humphries, Grace He, Shamiza Hussein, Lizhu Ke, Nevan Krogan, Zhijian Li, Joshua N Levinson, Hong Lu, Patrice Menard, Christella Munyana, Ainslie B Parsons, Owen Ryan, Raffi Tonikian, Tania Roberts, Anne-Marie Sdicu, Jesse Shapiro, Bilal Sheikh, Bernhard Suter, Sharyl L Wong, Lan V Zhang, Hongwei Zhu, Christopher G Burd, Sean Munro, Chris Sander, Jasper Rine, Jack Greenblatt, Matthias Peter, Anthony Bretscher, Graham Bell, Frederick P Roth, Grant W Brown, Brenda Andrews, Howard Bussey, Charles Boone
    posted to knockout save yeast by lyongu on 2005-11-01 18:10:59 as ***** along with 20 people and 2 groups czeller ldfu pcahan1 lfriedl luispedro opheliav tabu Chue nirfriedman nickluscombe koller raiyar patrycjam patrycja_missiuro jiny chasmand tresch Takayuki ksiek carlk kdl EBI-regulation
  • Mouse Ubc9 knockout: many path(way)s to ruin.
    Dev Cell, Vol. 9, No. 6. (December 2005), pp. 727-728.
    by MR Kuehn
    posted to outside mouse knockout by lusk on 2007-02-04 02:54:18 as **
  • Sound-induced seizures in serotonin 5-HT2c receptor mutant mice
    Nat Genet, Vol. 16, No. 4. (1997), pp. 387-390.
    by Thomas J Brennan, William W Seeley, Michael Kilgard, Christoph E Schreiner, Laurence H Tecott
    posted to serotonin mice knockout epilepsy audiogenicseizures 5ht2c by ksinnott on 2008-10-10 06:29:38 as **
  • 5-HT receptor knockouts: Constitutive, inducible or tissue-specific
    Seminars in Neuroscience, Vol. 7, No. 6. (December 1995), pp. 395-400.
    by R Grailhe
    posted to serotonin knockout 5ht by ksinnott on 2008-10-10 06:38:03 as **
  • Cre/loxP System for Generating Tissue-specific Knockout Mouse Models
    pp. 243-246.
    by Claudine H Kos
    posted to knockout by kpie on 2007-08-17 15:01:46 as ***
  • REVIEW ARTICLE: THE MOLECULAR ERA OF BLADDER RESEARCH. TRANSGENIC MICE AS EXPERIMENTAL TOOLS IN THE STUDY OF OUTLET OBSTRUCTION
    The Journal of Urology, Vol. 164, No. 1. (July 2000), pp. 170-179.
    by James A Bassuk, Richard Grady, Michael Mitchell
    posted to signaling obstruction mouse knockout bladder by kjglennie on 2008-09-18 02:50:47 as **
  • Guanylyl cyclase/natriuretic peptide receptor-A gene disruption causes increased adrenal angiotensin II and aldosterone levels
    Am J Physiol Renal Physiol, Vol. 293, No. 1. (1 July 2007), pp. F121-127.
    by Di Zhao, Elangovan Vellaichamy, Naveen K Somanna, Kailash N Pandey
    posted to anp cyclase guanylate knockout npr-a by kjglennie on 2008-04-11 04:10:23 as **
  • Pressure-independent cardiac hypertrophy in mice with cardiomyocyte-restricted inactivation of the atrial natriuretic peptide receptor guanylyl cyclase-A.
    The Journal of clinical investigation, Vol. 111, No. 9. (May 2003), pp. 1399-1407.
    by R Holtwick, M van Eickels, BV Skryabin, HA Baba, A Bubikat, F Begrow, MD Schneider, DL Garbers, M Kuhn
    posted to anp heart-specific hypertrophy knockout by kjglennie on 2008-04-12 03:19:29 as **
  • Elevated renal norepinephrine in proANP gene-disrupted mice is associated with increased tyrosine hydroxylase expression in sympathetic ganglia
    Regulatory Peptides, Vol. 143, No. 1-3. (4 October 2007), pp. 90-96.
    by Perrie F O'Tierney, Yat M Tse, Stephen C Pang
    posted to anp knockout norepinephrine pro-anp by kjglennie on 2008-04-10 22:31:17 as **
  • Hypertension in mice lacking the proatrial natriuretic peptide convertase corin.
    Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, No. 3. (18 January 2005), pp. 785-790.
    by JC Chan, O Knudson, F Wu, J Morser, WP Dole, Q Wu
    posted to anp corin hypertension knockout mice by kjglennie on 2008-04-15 01:22:45 as **
  • Biochemical analysis of neutral endopeptidase activity reveals independent catabolism of atrial and brain natriuretic peptide.
    Biological chemistry, Vol. 385, No. 2. (February 2004), pp. 179-184.
    by T Walther, H Stepan, K Pankow, M Becker, HP Schultheiss, WE Siems
    posted to anp cleavage enyzmatic knockout nep peptidase by kjglennie on 2008-04-09 15:38:28 as **
  • Salt-sensitive hypertension in ANP knockout mice: potential role of abnormal plasma renin activity
    Am J Physiol Regul Integr Comp Physiol, Vol. 274, No. 1. (1 January 1998), pp. R255-261.
    by LG Melo, AT Veress, CK Chong, SC Pang, TG Flynn, H Sonnenberg
    posted to anp knockout renin salt by kjglennie on 2008-04-11 03:52:47 as **
  • A protocol for constructing gene targeting vectors: generating knockout mice for the cadherin family and beyond.
    Nature protocols, Vol. 3, No. 6. (2008), pp. 1056-1076.
    by S Wu, G Ying, Q Wu, MR Capecchi
    posted to plasmid knockout gene-targeting by jyuh on 2008-08-12 11:04:04 as ** along with 1 person sebastien_vigneau
  • FOXO animal models reveal a variety of diverse roles for FOXO transcription factors.
    Oncogene, Vol. 27, No. 16. (7 April 2008), pp. 2345-2350.
    by KC Arden
    posted to knockout foxo by jyuh on 2008-04-27 04:21:29 as ** along with 1 person and 1 group tharris C. elegans / WormBase
  • Muscarinic acetylcholine receptors: mutant mice provide new insights for drug development
    Nature Reviews Drug Discovery, Vol. 6, No. 9., pp. 721-733.
    by Jürgen Wess, Richard M Eglen, Dinesh Gautam
    posted to muscarinic mouse knockout by jyuh on 2007-11-11 06:05:21 as ** along with 2 people and 2 groups kuhn dchughes G4ID Genetics-of-Gambling
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