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Tag hnf4 [92 articles]

Recent papers classified by the tag hnf4.
  • A transcriptional regulatory element common to a large family of hepatic cytochrome P450 genes is a functional binding site of the orphan receptor HNF-4.
    J Biol Chem, Vol. 269, No. 7. (18 February 1994), pp. 5420-5427.
    by D Chen, G Lepar, B Kemper
    posted to hnf4 s1a targets by yevishere on 2008-01-03 00:08:43 as **
  • Unique antiviral mechanism discovered in anti-hepatitis B virus research with a natural product analogue.
    Proc Natl Acad Sci U S A, Vol. 104, No. 20. (15 May 2007), pp. 8526-8531.
    by C Ying, Y Li, CH Leung, MD Robek, YC Cheng
    posted to diabetes hnf4 by yevishere on 2008-01-03 23:16:40 as **
  • Expansion of adult beta-cell mass in response to increased metabolic demand is dependent on HNF-4alpha.
    Genes Dev, Vol. 21, No. 7. (1 April 2007), pp. 756-769.
    by RK Gupta, N Gao, RK Gorski, P White, OT Hardy, K Rafiq, JE Brestelli, G Chen, CJ Stoeckert, KH Kaestner
    posted to hnf4 pancreas by yevishere on 2008-01-03 23:22:22 as **
  • P2 promoter variants of the hepatocyte nuclear factor 4alpha gene are associated with type 2 diabetes in Mexican Americans.
    Diabetes, Vol. 56, No. 2. (February 2007), pp. 513-517.
    by DM Lehman, DK Richardson, CP Jenkinson, KJ Hunt, TD Dyer, RJ Leach, R Arya, HE Abboud, J Blangero, R Duggirala, MP Stern
    posted to diabetes hnf4 mapping by yevishere on 2008-01-03 23:27:56 as **
  • Nuclear receptors and the regulation of drug-metabolizing enzymes and drug transporters: implications for interindividual variability in response to drugs.
    J Clin Pharmacol, Vol. 47, No. 5. (May 2007), pp. 566-578.
    by BL Urquhart, RG Tirona, RB Kim
    posted to drugs hnf4 toxicology by yevishere on 2008-01-03 23:18:50 as **
  • Hepatocyte nuclear factors 1alpha and 4alpha control expression of proline oxidase in adult liver.
    FEBS Lett, Vol. 578, No. 1-2. (3 December 2004), pp. 63-68.
    by A Kamiya, Y Inoue, T Kodama, FJ Gonzalez
    posted to hnf4 s1a targets by yevishere on 2008-01-03 00:57:43 as **
  • HNF4alpha and NF-E2 are key transcriptional regulators of the murine Abcc6 gene expression.
    Biochim Biophys Acta, Vol. 1759, No. 8-9. (p 2006), pp. 426-436.
    by V Douet, CM VanWart, MB Heller, S Reinhard, O Le Saux
    posted to hnf4 targets by yevishere on 2008-01-03 23:31:47 as **
  • Regulation of human protein Z gene expression by liver-enriched transcription factor HNF-4 and ubiquitous factor Sp1
    Journal of Thrombosis and Haemostasis, Vol. 5, No. 11. (November 2007), pp. 2250-2258.
    by H Sugawara, H Iwata, M Souri, A Ichinose
    posted to hnf4 targets by yevishere on 2008-01-02 23:27:33 as **
  • Differential regulation of constitutive androstane receptor expression by hepatocyte nuclear factor4alpha isoforms.
    Hepatology, Vol. 45, No. 5. (May 2007), pp. 1146-1153.
    by JM Pascussi, A Robert, A Moreau, J Ramos, P Bioulac-Sage, F Navarro, P Blanc, E Assenat, P Maurel, MJ Vilarem
    posted to hnf4 isoforms targets by yevishere on 2008-01-03 23:18:02 as **
  • Regulation of human hepatocyte gene expression by fatty acids.
    Biochem Biophys Res Commun, Vol. 362, No. 2. (19 October 2007), pp. 374-380.
    by CD Swagell, DC Henly, CP Morris
    posted to fattyacid hnf4 ligands by yevishere on 2008-01-02 23:42:40 as **
  • RSK4 and PAK5 are novel candidate genes in diabetic rat kidney and brain.
    Mol Pharmacol, Vol. 67, No. 3. (March 2005), pp. 604-611.
    by M Niehof, J Borlak
    posted to hnf4 s1a targets by yevishere on 2008-01-03 00:57:27 as **
  • Tissue-specific transcription factor HNF4alpha inhibits cell proliferation and induces apoptosis in the pancreatic INS-1 beta-cell line.
    Biol Chem, Vol. 388, No. 1. (January 2007), pp. 91-106.
    by S Erdmann, S Senkel, T Arndt, B Lucas, J Lausen, L Klein-Hitpass, GU Ryffel, H Thomas
    posted to expression hnf4 pancreas by yevishere on 2008-01-03 23:28:33 as **
  • Binding and activation of the human aldehyde dehydrogenase 2 promoter by hepatocyte nuclear factor 4.
    Biochim Biophys Acta, Vol. 1399, No. 2-3. (20 August 1998), pp. 181-186.
    by MJ Stewart, KM Dipple, M Estonius, H Nakshatri, LM Everett, DW Crabb
    posted to hnf4 targets by yevishere on 2008-01-03 00:00:54 as **
  • Deconvoluting the intestine: molecular evidence for a major role of the mesenchyme in the modulation of signaling cross talk.
    Physiol Genomics, Vol. 29, No. 3. (11 May 2007), pp. 290-301.
    by X Li, BB Madison, W Zacharias, A Kolterud, D States, DL Gumucio
    posted to hnf4 intestine targets by yevishere on 2008-01-03 23:26:06 as **
  • Nuclear receptor-mediated transcriptional regulation in Phase I, II, and III xenobiotic metabolizing systems.
    Drug Metab Pharmacokinet, Vol. 21, No. 6. (December 2006), pp. 437-457.
    by K Nakata, Y Tanaka, T Nakano, T Adachi, H Tanaka, T Kaminuma, T Ishikawa
    posted to hnf4 review toxicology by yevishere on 2008-01-03 23:41:18 as **
  • Transcriptional regulation of human apolipoprotein genes ApoB, ApoCIII, and ApoAII by members of the steroid hormone receptor superfamily HNF-4, ARP-1, EAR-2, and EAR-3.
    J Biol Chem, Vol. 267, No. 22. (5 August 1992), pp. 15849-15860.
    by JA Ladias, M Hadzopoulou-Cladaras, D Kardassis, P Cardot, J Cheng, V Zannis, C Cladaras
    posted to hnf4 s1a targets by yevishere on 2008-01-03 00:04:29 as **
  • Transcriptional control of the human biliary glycoprotein gene, a CEA gene family member down-regulated in colorectal carcinomas.
    Eur J Biochem, Vol. 223, No. 2. (15 July 1994), pp. 529-541.
    by W Hauck, P Nédellec, C Turbide, CP Stanners, TR Barnett, N Beauchemin
    posted to hnf4 s1a targets by yevishere on 2008-01-03 00:06:04 as **
  • Characterization of the human cytochrome P4502D6 promoter. A potential role for antagonistic interactions between members of the nuclear receptor family.
    J Biol Chem, Vol. 271, No. 41. (11 October 1996), pp. 25269-25276.
    by W Cairns, CA Smith, AW McLaren, CR Wolf
    posted to hnf4 s1a targets by yevishere on 2008-01-03 00:09:12 as **
  • Distal apolipoprotein C-III regulatory elements F to J act as a general modular enhancer for proximal promoters that contain hormone response elements. Synergism between hepatic nuclear factor-4 molecules bound to the proximal promoter and distal enhancer sites.
    Arterioscler Thromb Vasc Biol, Vol. 17, No. 1. (January 1997), pp. 222-232.
    by D Kardassis, I Tzameli, M Hadzopoulou-Cladaras, I Talianidis, V Zannis
    posted to hnf4 s1a targets by yevishere on 2008-01-03 00:05:55 as **
  • Search of type 2 diabetes susceptibility gene on chromosome 20q.
    Biochem Biophys Res Commun, Vol. 357, No. 4. (15 June 2007), pp. 1100-1106.
    by F Takeuchi, K Yanai, H Inomata, N Kuzuya, H Kajio, S Honjo, N Takeda, Y Kaburagi, K Yasuda, S Shirasawa, T Sasazuki, N Kato
    posted to diabetes hnf4 mapping by yevishere on 2008-01-03 23:17:32 as **
  • Rifampicin induction of CYP3A4 requires pregnane X receptor cross talk with hepatocyte nuclear factor 4alpha and coactivators, and suppression of small heterodimer partner gene expression.
    Drug Metab Dispos, Vol. 34, No. 5. (May 2006), pp. 756-764.
    by T Li, JY Chiang
    posted to hnf4 interactions targets by yevishere on 2008-01-02 23:38:02 as **
  • Effects of hepatocyte nuclear factor-4alpha on the regulation of the hepatic acute phase response.
    J Mol Biol, Vol. 371, No. 2. (10 August 2007), pp. 323-335.
    by Z Wang, PA Burke
    posted to expresion hnf4 by yevishere on 2008-01-03 23:54:04 as **
  • Hepatic HNF4alpha deficiency induces periportal expression of glutamine synthetase and other pericentral enzymes.
    Hepatology, Vol. 45, No. 2. (February 2007), pp. 433-444.
    by VS Stanulović, I Kyrmizi, M Kruithof-de Julio, M Hoogenkamp, JL Vermeulen, JM Ruijter, I Talianidis, TB Hakvoort, WH Lamers
    posted to expression hnf4 targets by yevishere on 2008-01-03 23:27:20 as **
  • The human mucin MUC4 is transcriptionally regulated by caudal-related homeobox, hepatocyte nuclear factors, forkhead box A, and GATA endodermal transcription factors in epithelial cancer cells.
    J Biol Chem, Vol. 282, No. 31. (3 August 2007), pp. 22638-22650.
    by N Jonckheere, A Vincent, M Perrais, MP Ducourouble, AK Male, JP Aubert, P Pigny, KL Carraway, JN Freund, IB Renes, I Van Seuningen
    posted to hnf4 targets by yevishere on 2008-01-03 23:10:45 as **
  • Association of genetic variations near P2 promoter of the hepatocyte nuclear factor-4alpha gene and insulin secretion index in Thais.
    Acta Diabetol, Vol. 44, No. 4. (December 2007), pp. 227-232.
    by W Jongjaroenprasert, S Chanprasertyothin, A Kongsuksai, P Bunnag, G Puavilai, B Ongphiphadhanakul
    posted to diabetes hnf4 by yevishere on 2008-01-02 23:36:40 as **
  • Transactivation of the human apolipoprotein CII promoter by orphan and ligand-dependent nuclear receptors. The regulatory element CIIC is a thyroid hormone response element.
    J Biol Chem, Vol. 273, No. 28. (10 July 1998), pp. 17810-17816.
    by D Kardassis, E Sacharidou, VI Zannis
    posted to hnf4 s1a targets by yevishere on 2008-01-03 00:05:19 as **
  • Characterization of three growth hormone-responsive transcription factors preferentially expressed in adult female liver.
    Endocrinology, Vol. 148, No. 7. (July 2007), pp. 3327-3337.
    by EV Laz, MG Holloway, CS Chen, DJ Waxman
    posted to expression hnf4 microarray by yevishere on 2008-01-03 23:20:58 as **
  • Hepatocyte nuclear factor 4-mediated activation of rat CYP3A1 gene and its modes of modulation by apolipoprotein AI regulatory protein I and v-ErbA-related protein 3.
    Arch Biochem Biophys, Vol. 362, No. 1. (1 February 1999), pp. 32-37.
    by M Ogino, K Nagata, M Miyata, Y Yamazoe
    posted to hnf4 s1a targets by yevishere on 2008-01-03 00:09:21 as **
  • An array of binding sites for hepatocyte nuclear factor 4 of high and low affinities modulates the liver-specific enhancer for the human alpha1-microglobulin/bikunin precursor.
    Biochem J, Vol. 334 ( Pt 3) (15 September 1998), pp. 577-584.
    by P Rouet, G Raguenez, P Ruminy, JP Salier
    posted to hnf4 targets by yevishere on 2008-01-03 00:00:14 as **
  • HNF-4 increases activity of the rat Apo A1 gene.
    Nucleic Acids Res, Vol. 21, No. 5. (11 March 1993), pp. 1205-1211.
    by J Chan, H Nakabayashi, NC Wong
    posted to hnf4 s1a targets by yevishere on 2008-01-03 00:04:04 as **
  • Orphan receptor HNF-4 and bZip protein C/EBP alpha bind to overlapping regions of the apolipoprotein B gene promoter and synergistically activate transcription.
    J Biol Chem, Vol. 268, No. 22. (5 August 1993), pp. 16831-16838.
    by S Metzger, JL Halaas, JL Breslow, FM Sladek
    posted to hnf4 s1a targets by yevishere on 2008-01-03 00:04:53 as **
  • The human organic cation transporter-1 gene is transactivated by hepatocyte nuclear factor-4alpha.
    J Pharmacol Exp Ther, Vol. 317, No. 2. (May 2006), pp. 778-785.
    by M Saborowski, GA Kullak-Ublick, JJ Eloranta
    posted to hnf4 s1a targets by yevishere on 2008-01-03 00:53:22 as **
  • Age-related changes in bile acid synthesis and hepatic nuclear receptor expression
    European Journal of Clinical Investigation, Vol. 37, No. 6. (June 2007), pp. 501-508.
    by Bertolotti, , Gabbi, , Anzivino, , Crestani, , Mitro, , Del Puppo, , Godio, , De Fabiani, , Macchioni, , Carulli, , Rossi, , Ricchi, , Loria, , Carulli,
    posted to aging hnf4 by yevishere on 2008-01-03 23:11:55 as **
  • Positive and negative regulation of human hepatic hydroxysteroid sulfotransferase (SULT2A1) gene transcription by rifampicin: roles of hepatocyte nuclear factor 4alpha and pregnane X receptor.
    J Pharmacol Exp Ther, Vol. 323, No. 2. (November 2007), pp. 586-598.
    by HL Fang, SC Strom, E Ellis, Z Duanmu, J Fu, Z Duniec-Dmuchowski, CN Falany, JL Falany, TA Kocarek, M Runge-Morris
    posted to hnf4 targets by yevishere on 2008-01-02 23:43:33 as **
  • Activity of the human aldehyde dehydrogenase 2 promoter is influenced by the balance between activation by hepatocyte nuclear factor 4 and repression by perosixome proliferator activated receptor delta, chicken ovalbumin upstream promoter-transcription factor, and apolipoprotein regulatory protein-1.
    Adv Exp Med Biol, Vol. 463 (1999), pp. 115-121.
    by J Pinaire, WY Chou, M Stewart, K Dipple, D Crabb
    posted to hnf4 targets by yevishere on 2008-01-03 00:00:43 as **
  • The peroxisome proliferator response element (PPRE) present at positions -681/-669 in the rat liver 3-ketoacyl-CoA thiolase B gene functionally interacts differently with PPARalpha and HNF-4.
    Biochem Biophys Res Commun, Vol. 269, No. 2. (16 March 2000), pp. 347-351.
    by V Nicolas-Frances, VK Dasari, E Abruzzi, T Osumi, N Latruffe
    posted to hnf4 targets by yevishere on 2008-01-02 23:59:46 as **
  • Transcriptional regulation of the apolipoprotein A-IV gene involves synergism between a proximal orphan receptor response element and a distant enhancer located in the upstream promoter region of the apolipoprotein C-III gene.
    Nucleic Acids Res, Vol. 22, No. 22. (11 November 1994), pp. 4689-4696.
    by E Ktistaki, JM Lacorte, N Katrakili, VI Zannis, I Talianidis
    posted to hnf4 s1a targets by yevishere on 2008-01-03 00:04:41 as **
  • Liver-enriched transcription factor HNF-4 is a novel member of the steroid hormone receptor superfamily.
    Genes Dev, Vol. 4, No. 12B. (December 1990), pp. 2353-2365.
    by FM Sladek, WM Zhong, E Lai, JE Darnell
    posted to hnf4 s1a targets by yevishere on 2008-01-03 00:05:32 as **
  • Hepatocyte nuclear factor 1 alpha and 4 alpha are factors involved in interindividual variability in the expression of UGT1A6 and UGT1A9 but not UGT1A1, UGT1A3 and UGT1A4 mRNA in human livers.
    Drug Metab Pharmacokinet, Vol. 22, No. 5. (October 2007), pp. 391-398.
    by S Aueviriyavit, T Furihata, K Morimoto, K Kobayashi, K Chiba
    posted to hnf4 targets by yevishere on 2008-01-02 23:27:51 as **
  • Nuclear Receptor Hepatocyte Nuclear Factor 4alpha1 Competes with Oncoprotein c-Myc for Control of the p21/WAF1 Promoter.
    Mol Endocrinol, Vol. 22, No. 1. (January 2008), pp. 78-90.
    by WW Hwang-Verslues, FM Sladek
    posted to hnf4 interactions targets by yevishere on 2008-01-02 23:33:38 as **
  • Differential protein binding and transcriptional activities of HNF-4 elements in three closely related CYP2C genes.
    DNA Cell Biol, Vol. 13, No. 7. (July 1994), pp. 771-779.
    by D Chen, Y Park, B Kemper
    posted to hnf4 s1a targets by yevishere on 2008-01-03 00:06:47 as **
  • The expression profiles of nuclear receptors in the developing and adult kidney.
    Mol Endocrinol, Vol. 20, No. 12. (December 2006), pp. 3412-3420.
    by JM Suh, CT Yu, K Tang, T Tanaka, T Kodama, MJ Tsai, SY Tsai
    posted to expression hnf4 kidney by yevishere on 2008-01-03 23:33:03 as **
  • A 700-bp fragment of the human antithrombin III promoter is sufficient to confer high, tissue-specific expression on human apolipoprotein A-II in transgenic mice.
    Gene, Vol. 156, No. 2. (24 April 1995), pp. 199-205.
    by GL Tremp, N Duchange, D Branellec, S Cereghini, A Tailleux, L Berthou, C Fievet, N Touchet, B Schombert, JC Fruchart
    posted to hnf4 targets by yevishere on 2008-01-03 00:03:36 as **
  • MotifCut: regulatory motifs finding with maximum density subgraphs.
    Bioinformatics, Vol. 22, No. 14. (15 July 2006)
    by E Fratkin, BT Naughton, DL Brutlag, S Batzoglou
    posted to chipchip hnf4 mining by yevishere on 2008-01-03 23:50:00 as ** along with 1 person and 1 group indigoviolet EisenLab
  • Positional bias of general and tissue-specific regulatory motifs in mouse promoters
    BMC Genomics, Vol. 8, No. 1. (2007)
    by Nicolas Bellora, Domenec Farre, Mar
    posted to hnf4 motif prediction by yevishere on 2008-01-02 23:15:28 as ** along with 3 people maximilianh barriot gjuggler
  • Cooperative interaction between hepatocyte nuclear factor 4 alpha and GATA transcription factors regulates ATP-binding cassette sterol transporters ABCG5 and ABCG8.
    Mol Cell Biol, Vol. 27, No. 12. (June 2007), pp. 4248-4260.
    by K Sumi, T Tanaka, A Uchida, K Magoori, Y Urashima, R Ohashi, H Ohguchi, M Okamura, H Kudo, K Daigo, T Maejima, N Kojima, I Sakakibara, S Jiang, G Hasegawa, I Kim, TF Osborne, M Naito, FJ Gonzalez, T Hamakubo, T Kodama, J Sakai
    posted to hnf4 interactions modulation by yevishere on 2008-01-03 23:22:00 as **
  • HNF4A genetic variants: role in diabetes.
    Curr Opin Clin Nutr Metab Care, Vol. 10, No. 4. (July 2007), pp. 397-402.
    by L Love-Gregory, MA Permutt
    posted to diabetes hnf4 review by yevishere on 2008-01-03 23:09:04 as **
  • Genegene interactions between HNF4A and KCNJ11 in predicting Type 2 diabetes in women
    Diabetic Medicine, Vol. 24, No. 11. (November 2007), pp. 1187-1191.
    by Qi, , Van Dam, , Asselbergs, , Hu,
    posted to diabetes hnf4 by yevishere on 2008-01-02 23:33:05 as **
  • Identification of transcriptional regulators using binding site enrichment analysis.
    In Silico Biol, Vol. 6, No. 6. (2006), pp. 531-544.
    by TM Kim, MH Jung
    posted to enrichment hnf4 mining motif by yevishere on 2008-01-03 23:14:06 as **** along with 1 person heliopais
  • Novel genetic variations and haplotypes of hepatocyte nuclear factor 4alpha (HNF4A) found in Japanese type II diabetic patients.
    Drug Metab Pharmacokinet, Vol. 21, No. 4. (August 2006), pp. 337-346.
    by H Fukushima-Uesaka, Y Saito, K Maekawa, M Saeki, N Kamatani, H Kajio, N Kuzuya, K Yasuda, J Sawada
    posted to diabetes hnf4 mapping mutant by yevishere on 2008-01-03 23:34:21 as **
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