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Tag dna-damage [85 articles]

Recent papers classified by the tag dna-damage.
  • Stress and mTORture signaling.
    Oncogene, Vol. 25, No. 48. (16 October 2006), pp. 6373-6383.
    by JH Reiling, DM Sabatini
    posted to dna-damage mtor review stress by zhlei on 2008-08-25 20:47:20 as ** along with 2 people jyuh jjohnson17
  • A chromatin-wide transition to H4K20 monomethylation impairs genome integrity and programmed DNA rearrangements in the mouse.
    Genes & development, Vol. 22, No. 15. (1 August 2008), pp. 2048-2061.
    by G Schotta, R Sengupta, S Kubicek, S Malin, M Kauer, E Callén, A Celeste, M Pagani, S Opravil, IA De La Rosa-Velazquez, A Espejo, MT Bedford, A Nussenzweig, M Busslinger, T Jenuwein
    posted to dna-damage dna-repair h4k20 methylation monomethylation by zhlei on 2008-08-07 23:24:43 as **
  • Signaling mechanisms involved in the response to genotoxic stress and regulating lifespan.
    Int J Biochem Cell Biol, Vol. 40, No. 2. (2008), pp. 176-180.
    by LJ Niedernhofer, PD Robbins
    posted to aging dna-damage review sirt1 by zhlei on 2008-03-28 20:12:20 as ** along with 1 person jyuh
  • Hop1 and the meiotic DNA-damage response.
    Cell, Vol. 132, No. 5. (7 March 2008), pp. 731-732.
    by N Hunter
    posted to dna-damage hop1 meiosis by zhlei on 2008-03-26 21:05:12 as **
  • Interactions between E2F1 and SirT1 regulate apoptotic response to DNA damage
    Nature Cell Biology, Vol. 8, No. 9. (06 August 2006), pp. 1025-1031.
    by Chuangui Wang, Lihong Chen, Xinghua Hou, Zhenyu Li, Neha Kabra, Yihong Ma, Shino Nemoto, Toren Finkel, Wei Gu, Douglas W Cress, Jiandong Chen
    posted to dna-damage e2f1 sirt1 by zhlei on 2007-11-05 20:42:24 as **
  • DNA repair, insulin signaling and sirtuins: at the crossroads between cancer and aging.
    Frontiers in bioscience : a journal and virtual library, Vol. 13 (2008), pp. 6966-6990.
    by R Mostoslavsky
    posted to aging cancer dna-damage ifg1 insulin review sirtuin by zhlei on 2008-07-08 20:32:15 as read along with 1 person and 1 group Zephyrus Roswell Cancer Crosstalk
  • Chromatin challenges during DNA replication and repair.
    Cell, Vol. 128, No. 4. (23 February 2007), pp. 721-733.
    by A Groth, W Rocha, A Verreault, G Almouzni
    posted to chromatin chromatin-remodeling-modification dna-damage repair review by zhlei on 2007-11-24 02:58:27 as ** along with 1 person sebastien_vigneau
  • A Functional Link Between SIRT1 Deacetylase and NBS1 in DNA Damage Response.
    Cell Cycle, Vol. 6, No. 23. (7 September 2007)
    by Zhigang Yuan, Edward Seto
    posted to deacetylation dna-damage sirt1 by zhlei on 2007-12-28 14:42:01 as **
  • Acetylation by Tip60 is required for selective histone variant exchange at DNA lesions.
    Science, Vol. 306, No. 5704. (17 December 2004), pp. 2084-2087.
    by T Kusch, L Florens, WH Macdonald, SK Swanson, RL Glaser, JR Yates, SM Abmayr, MP Washburn, JL Workman
    posted to chromatin chromatin-remodeling-modification dna-damage drosophila h2a h2av tip60 by zhlei on 2007-12-14 20:33:50 as **
  • The DNA Damage Response: Ten Years After
    Molecular Cell, Vol. 28, No. 5. (14 December 2007), pp. 739-745.
    by Wade J Harper, Stephen J Elledge
    posted to chromatin chromatin-remodeling-modification dna-damage review by zhlei on 2007-12-18 23:50:27 as **** along with 2 people jyuh TOchi
  • SIRT1 sumoylation regulates its deacetylase activity and cellular response to genotoxic stress
    Nature Cell Biology, Vol. 9, No. 11. (14 October 2007), pp. 1253-1262.
    by Yonghua Yang, Wei Fu, Jiandong Chen, Nancy Olashaw, Xiaohong Zhang, Santo V Nicosia, Kapil Bhalla, Wenlong Bai
    posted to deacetylation dna-damage modification sirt1 sirtuin stress sumoylation by zhlei on 2008-01-06 19:43:22 as ** along with 1 person jyuh
  • Early steps in the DNA base excision/single-strand interruption repair pathway in mammalian cells.
    Cell Res (1 January 2008)
    by Muralidhar L L Hegde, Tapas K K Hazra, Sankar Mitra
    posted to ber dna-damage repair review by zhlei on 2008-01-02 22:00:38 as **
  • Early Events in the Mammalian Response to DNA Double-Strand Breaks
    Mutagenesis (21 July 2008), gen039.
    by Lucy C Riches, Anthony M Lynch, Nigel J Gooderham
    posted to dna-damage review by zhlei on 2008-07-24 02:35:05 as **
  • Down-regulation of a SILENT INFORMATION REGULATOR2-related histone deacetylase gene, OsSRT1, induces DNA fragmentation and cell death in rice.
    Plant physiology, Vol. 144, No. 3. (July 2007), pp. 1508-1519.
    by L Huang, Q Sun, F Qin, C Li, Y Zhao, DX Zhou
    posted to dimethylation dna-damage h3k9 methylation plant sirt2 by zhlei on 2008-08-06 18:05:50 as **
  • The role of the DNA damage response pathways in brain development and microcephaly: Insight from human disorders
    DNA Repair, Vol. In Press, Corrected Proof
    by Mark O'Driscoll, Penny A Jeggo
    posted to dna-damage review by zhlei on 2008-07-07 17:30:30 as ** along with 1 person TOchi
  • DNA damage signalling guards against activated oncogenes and tumour progression.
    Oncogene, Vol. 26, No. 56. (10 December 2007), pp. 7773-7779.
    by J Bartek, J Bartkova, J Lukas
    posted to cancer dna-damage review by zhlei on 2008-07-07 17:56:00 as ** along with 3 people Zephyrus catcremona jyuh
  • What histone code for DNA repair?
    Mutation Research/Reviews in Mutation Research, Vol. In Press, Corrected Proof
    by Alexandre E Escargueil, Daniele G Soares, Mirian Salvador, Annette K Larsen, Joao A Henriques
    posted to review histone-modification histone dna-repair dna-damage by zhlei on 2008-09-16 20:55:12 as ** along with 1 person TOchi
  • p53 Target Genes Sestrin1 and Sestrin2 Connect Genotoxic Stress and mTOR Signaling
    Cell, Vol. 134, No. 3. (8 August 2008), pp. 451-460.
    by Andrei V Budanov, Michael Karin
    posted to dna-damage dna-repair mtor p53 by zhlei on 2008-08-08 17:04:55 as ** along with 2 people sarahazl jyuh
  • Structure and mechanism for DNA lesion recognition.
    Cell Res (24 December 2007)
    by Wei Yang
    posted to dna-damage by zhlei on 2007-12-28 14:42:20 as **
  • Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks.
    J Cell Biol, Vol. 173, No. 2. (24 April 2006), pp. 195-206.
    by S Bekker-Jensen, C Lukas, R Kitagawa, F Melander, MB Kastan, J Bartek, J Lukas
    posted to atm atr dna-damage dna-pk by zhlei on 2008-04-29 17:59:25 as ** along with 1 person DNAReplication
  • The DNA damage response pathways: at the crossroad of protein modifications.
    Cell Res, Vol. 18, No. 1. (January 2008), pp. 8-16.
    by MS Huen, J Chen
    posted to dna-damage by zhlei on 2008-04-25 19:23:58 as ** along with 1 person jyuh
  • Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks
    Nature, Vol. 432, No. 7015. (18 November 2004), pp. 406-411.
    by Yentram Huyen, Omar Zgheib, Ditullio, Vassilis G Gorgoulis, Panayotis Zacharatos, Tom J Petty, Emily A Sheston, Hestia S Mellert, Elena S Stavridi, Thanos D Halazonetis
    posted to 53bp1 crb2 dna-damage dsb h3k79 histone histone-modification methylation rad9 by zhlei on 2007-12-14 18:12:16 as ** along with 2 people DNAReplication elzodw
  • ATM and ATR Substrate Analysis Reveals Extensive Protein Networks Responsive to DNA Damage
    Science, Vol. 316, No. 5828. (25 May 2007), pp. 1160-1166.
    by Shuhei Matsuoka, Bryan A Ballif, Agata Smogorzewska, Robert E Mcdonald, Kristen E Hurov, Ji Luo, Corey E Bakalarski, Zhenming Zhao, Nicole Solimini, Yaniv Lerenthal, Yosef Shiloh, Steven P Gygi, Stephen J Elledge
    posted to atm atr dna-damage phosphorylation by zhlei on 2007-12-20 22:37:35 as ** along with 8 people and 1 group jyuh ahab2001 jfr cactus stonest lonettma RyanGray taten 801
  • Tumor suppressor HIC1 directly regulates SIRT1 to modulate p53-dependent DNA-damage responses.
    Cell, Vol. 123, No. 3. (4 November 2005), pp. 437-448.
    by WY Chen, DH Wang, RC Yen, J Luo, W Gu, SB Baylin
    posted to dna-damage hic1 sirt1 by zhlei on 2007-11-06 03:50:19 as **
  • gamma-H2AX in recognition and signaling of DNA double-strand breaks in the context of chromatin
    Nucl. Acids Res., Vol. 36, No. 17. (1 October 2008), pp. 5678-5694.
    by Andrea Kinner, Wenqi Wu, Christian Staudt, George Iliakis
    posted to h2ax dna-repair dna-damage by zhlei on 2008-10-01 00:13:44 as **
  • RNF8 Transduces the DNA-Damage Signal via Histone Ubiquitylation and Checkpoint Protein Assembly.
    Cell, Vol. 131, No. 5. (30 November 2007), pp. 901-914.
    by MS Huen, R Grant, I Manke, K Minn, X Yu, MB Yaffe, J Chen
    posted to chromatin chromatin-remodeling-modification dna-damage h2ax histone phosphorylation rnf8 ubiquitin ubiquitination by zhlei on 2007-12-13 16:31:38 as read
  • Heterochromatin is refractory to gamma-H2AX modification in yeast and mammals
    J. Cell Biol., Vol. 178, No. 2. (16 July 2007), pp. 209-218.
    by Jung-Ae Kim, Michael Kruhlak, Farokh Dotiwala, Andre Nussenzweig, James E Haber
    posted to chromatin chromatin-remodeling-modification dna-damage h2a h2ax histone phosphorylation yeast by zhlei on 2007-12-19 20:35:32 as **
  • The deacetylase HDAC6 is a novel critical component of stress granules involved in the stress response
    Genes Dev., Vol. 21, No. 24. (15 December 2007), pp. 3381-3394.
    by Sohee Kwon, Yu Zhang, Patrick Matthias
    posted to dna-damage g3bp by zhlei on 2008-04-10 19:14:12 as ** along with 1 person kbjcflyer
  • Phosphorylation of HuR by Chk2 regulates SIRT1 expression.
    Mol Cell, Vol. 25, No. 4. (23 February 2007), pp. 543-557.
    by K Abdelmohsen, R Pullmann, A Lal, HH Kim, S Galban, X Yang, JD Blethrow, M Walker, J Shubert, DA Gillespie, H Furneaux, M Gorospe
    posted to dna-damage sirt1 by zhlei on 2007-11-06 04:05:06 as **
  • Hypoxia and metabolism: Hypoxia, DNA repair and genetic instability.
    Nat Rev Cancer (14 February 2008)
    by Robert G G Bristow, Richard P P Hill
    posted to dna-damage hypoxia review by zhlei on 2008-02-15 20:51:58 as ** along with 1 person jyuh
  • Essential role for nuclear PTEN in maintaining chromosomal integrity.
    Cell, Vol. 128, No. 1. (12 January 2007), pp. 157-170.
    by WH Shen, AS Balajee, J Wang, H Wu, C Eng, PP Pandolfi, Y Yin
    posted to akt dna-damage pten by zhlei on 2007-11-06 03:15:08 as **
  • Chromatin dynamics and the preservation of genetic information
    Nature, Vol. 447, No. 7147. (21 June 2007), pp. 951-958.
    by Jessica A Downs, Michel C Nussenzweig, Andre Nussenzweig
    posted to chromatin-remodeling-modification dna-damage histone review by zhlei on 2007-11-05 20:10:18 as **** along with 5 people and 2 groups dchughes cjeans epigenetics koichiy Petersarkies G4ID Genetics-of-Gambling
  • PKB[alpha]/Akt1 Acts Downstream of DNA-PK in the DNA Double-Strand Break Response and Promotes Survival
    Molecular Cell, Vol. 30, No. 2. (25 April 2008), pp. 203-213.
    by Lana Bozulic, Banu Surucu, Debby Hynx, Brian A Hemmings
    posted to akt dna-damage by zhlei on 2008-04-28 23:04:28 as ** along with 1 person jyuh
  • notes DNA damage checkpoint control in cells exposed to ionizing radiation.
    Oncogene, Vol. 22, No. 37. (1 September 2003), pp. 5834-5847.
    by G Iliakis, Y Wang, J Guan, H Wang
    posted to atm chk dna-damage by sam on 2004-11-09 19:48:24
  • DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation.
    Nature, Vol. 421, No. 6922. (30 January 2003), pp. 499-506.
    by CJ Bakkenist, MB Kastan
    posted to atm dna-damage s by sam on 2004-11-09 20:11:37 along with 1 person DNAReplication
  • Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints.
    Annu Rev Biochem, Vol. 73 (2004), pp. 39-85.
    by A Sancar, LA Lindsey-Boltz, K Unsal-Kaçmaz, S Linn
    posted to atm chk2 dna-damage by sam on 2004-11-09 19:47:48 along with 3 people and 1 group bisaj ecattell RyanGray 801
  • Recurrent Initiation: A Mechanism for Triggering p53 Pulses in Response to DNA Damage
    Molecular Cell, Vol. 30, No. 3. (9 May 2008), pp. 277-289.
    by Eric Batchelor, Caroline S Mock, Irun Bhan, Alexander Loewer, Galit Lahav
    posted to dna-damage by renatomilani on 2008-05-09 12:43:34 as ** along with 1 person tibbitts
  • Colocalization of Sensors Is Sufficient to Activate the DNA Damage Checkpoint in the Absence of Damage
    Molecular Cell, Vol. 30, No. 3. (9 May 2008), pp. 267-276.
    by Carla Y Bonilla, Justine A Melo, David P Toczyski
    posted to dna-damage by renatomilani on 2008-05-09 12:43:14 as **
  • Mdm2 Promotes Genetic Instability and Transformation Independent of p53
    Mol. Cell. Biol., Vol. 28, No. 15. (1 August 2008), pp. 4862-4874.
    by Alyssa Bouska, Tamara Lushnikova, Silvia Plaza, Christine M Eischen
    posted to cancer dna-damage journalclub mdm2 by mapplab on 2008-08-07 19:56:52 as **
  • TOR Signaling is a Determinant of Cell Survival in Response to DNA Damage.
    Mol Cell Biol (13 August 2007)
    by Changxian Shen, Cynthia S S Lancaster, Bin Shi, Hong Guo, Padma Thimmaiah, Mary-Ann A Bjornsti
    posted to dna-damage mtor by jyuh on 2007-09-22 03:31:52 as **
  • How to reduce false positive results when undertaking in vitro genotoxicity testing and thus avoid unnecessary follow-up animal tests: Report of an ECVAM Workshop.
    Mutat Res, Vol. 628, No. 1. (30 March 2007), pp. 31-55.
    by D Kirkland, S Pfuhler, D Tweats, M Aardema, R Corvi, F Darroudi, A Elhajouji, H Glatt, P Hastwell, M Hayashi, P Kasper, S Kirchner, A Lynch, D Marzin, D Maurici, JR Meunier, L Müller, G Nohynek, J Parry, E Parry, V Thybaud, R Tice, J van Benthem, P Vanparys, P White
    posted to dna-damage comet-assay by jyuh on 2007-10-12 05:15:13 as ** along with 1 person wandall
  • Genistein protects methylglyoxal-induced oxidative DNA damage and cell injury in human mononuclear cells.
    Toxicology in vitro : an international journal published in association with BIBRA, Vol. 21, No. 3. (April 2007), pp. 335-342.
    by HJ Wu, WH Chan
    posted to soy pbmc mgo dna-damage by jyuh on 2008-09-27 06:10:22 as **
  • Lead contamination results in late and slowly repairable DNA double-strand breaks and impacts upon the ATM-dependent signaling pathways.
    Toxicology letters, Vol. 173, No. 3. (28 September 2007), pp. 201-214.
    by J Gastaldo, M Viau, Z Bencokova, A Joubert, AM Charvet, J Balosso, N Foray
    posted to atm dna-damage lead by jyuh on 2008-08-31 10:47:35 as **
  • The comet assay in human biomonitoring: gene-environment interactions.
    Mutagenesis, Vol. 23, No. 3. (May 2008), pp. 191-205.
    by M Dusinska, AR Collins
    posted to comet dna-damage gene-environment by jyuh on 2008-08-05 05:17:26 as **
  • Oxidative DNA damage and plasma antioxidant capacity in type 2 diabetic patients with good and poor glycaemic control.
    Mutat Res, Vol. 638, No. 1-2. (1 February 2008), pp. 98-102.
    by M Lodovici, L Giovannelli, V Pitozzi, E Bigagli, G Bardini, CM Rotella
    posted to ros dna-damage dm comet-assay by jyuh on 2008-02-24 01:16:50 as **
  • Functional interaction between FOXO3a and ATM regulates DNA damage response
    Nature Cell Biology, Vol. 10, No. 4. (16 March 2008), pp. 460-467.
    by Wen-Bin Tsai, Young M Chung, Yoko Takahashi, Zhaohui Xu, Mickey CT Hu
    posted to atm dna-damage foxo by jyuh on 2008-05-07 08:07:22 as **
  • DNA repair pathways as targets for cancer therapy.
    Nat Rev Cancer (7 February 2008)
    by Thomas Helleday, Eva Petermann, Cecilia Lundin, Ben Hodgson, Ricky A A Sharma
    posted to cancer dna-damage by jyuh on 2008-03-03 03:12:15 as ** along with 4 people TOchi renatomilani Petersarkies dbs
  • The DNA repair complex DNA-PK, a pharmacological target in cancer chemotherapy and radiotherapy.
    Pathologie-biologie, Vol. 54, No. 4. (May 2006), pp. 185-193.
    by B Salles, P Calsou, P Frit, C Muller
    posted to dna-damage dna-pk by jyuh on 2008-08-24 06:43:35 as **
  • DNA damage, cellular senescence and organismal ageing: causal or correlative?
    Nucl. Acids Res. (2 October 2007), gkm681.
    by Jian-Hua Chen, Nicholes C Hales, Susan E Ozanne
    posted to aging dna-damage senescence by jyuh on 2007-10-12 03:03:04 as **
  • Mechanism of Oxidative DNA damage in diabetes: tuberin inactivation and downregulation of DNA repair enzyme OGG1.
    Diabetes (3 July 2008)
    by Simona Simone, Yves Gorin, Chakradhar Velagapudi, Hanna E E Abboud, Samy L L Habib
    posted to tuberin ros pt hg dna-damage dm akt by jyuh on 2008-08-24 05:47:23 as **
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