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algorithm alignment analysis anchored arabidopsis background benchmarking binding bioperl blocks cell chip cis-regulatory clustering combinatorial comparative composite comprative computational computing consensus conservation content cross-species cycle database dataset dependencies dependency deterministic discovery discriminative divergence dropsophila drosophila dsom ecoli encoding energy enhancers ensemble entropy eukaryotic evaluation evolution evolutionary familial feature filtering footprinting function functional genetic genome genomic genomics gibbs graph heirarchical hidden hierarchical hmm hypergeometric important information jaspar kononen learning length likelihood local machine map markov match matching matrix maximum measure mechanics melanogaster merging metric microarray mixture model modeling motif motifs multiple muscle mutual network neural neutral new noise nucleosome organizing phylogenetic plant position prediction profile progressive prokaryotic promoter protein p-value recognition regulation review roc rules sampling scoring search selection self semi-supervised sequence shannon signal significance significant similarity site sites soft speed stability statistical statistics structural survey thaliana theoretical theory tool tools two unknown unsupervised up web weight xxx yeast