Having a BLAST with bioinformatics (and avoiding BLASTphemy).

by: A Pertsemlidis, JW Fondon

Genome Biol, Vol. 2, No. 10. (2001)

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Abstract

Searching for similarities between biological sequences is the principal means by which bioinformatics contributes to our understanding of biology. Of the various informatics tools developed to accomplish this task, the most widely used is BLAST, the basic local alignment search tool. This article discusses the principles, workings, applications and potential pitfalls of BLAST, focusing on the implementation developed at the National Center for Biotechnology Information.

@article{citeulike:83434, abstract = {Searching for similarities between biological sequences is the principal means by which bioinformatics contributes to our understanding of biology. Of the various informatics tools developed to accomplish this task, the most widely used is BLAST, the basic local alignment search tool. This article discusses the principles, workings, applications and potential pitfalls of BLAST, focusing on the implementation developed at the National Center for Biotechnology Information.}, address = {Eugene McDermott Center for Human Growth and Development, University of Texas Southwestern Medical Center, Dallas, TX 75390-8591, USA. Alexander.Pertsemlidis@UTSouthwestern.edu}, author = {Pertsemlidis, A. and Fondon, J. W. }, citeulike-article-id = {83434}, doi = {http://dx.doi.org/10.1186/gb-2001-2-10-reviews2002}, issn = {1465-6914}, journal = {Genome Biol}, keywords = {bioinformatics, genomics}, number = {10}, posted-at = {2007-10-18 17:42:00}, priority = {5}, title = {Having a BLAST with bioinformatics (and avoiding BLASTphemy).}, url = {http://dx.doi.org/10.1186/gb-2001-2-10-reviews2002}, volume = {2}, year = {2001} }

RIS record

TY - JOUR ID - citeulike:83434 L3 - citeulike-article-id:83434 TI - Having a BLAST with bioinformatics (and avoiding BLASTphemy). JF - Genome Biol VL - 2 IS - 10 AD - Eugene McDermott Center for Human Growth and Development, University of Texas Southwestern Medical Center, Dallas, TX 75390-8591, USA. Alexander.Pertsemlidis@UTSouthwestern.edu SN - 1465-6914 N2 - Searching for similarities between biological sequences is the principal means by which bioinformatics contributes to our understanding of biology. Of the various informatics tools developed to accomplish this task, the most widely used is BLAST, the basic local alignment search tool. This article discusses the principles, workings, applications and potential pitfalls of BLAST, focusing on the implementation developed at the National Center for Biotechnology Information. KW - bioinformatics KW - genomics AU - Pertsemlidis, A AU - Fondon, JW PY - 2001/// UR - http://dx.doi.org/10.1186/gb-2001-2-10-reviews2002 ER -

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