New types of conserved sequence domains in DNA-binding regions of homing endonucleases.

@article{citeulike:456125, abstract = {We have identified four new types of short conserved sequence domains in homing endonucleases and related proteins. These domains are modular, appearing in various combinations. One domain includes a motif known by structure as a novel sequence-specific DNA-binding helix. Sequence similarity shows two other domains to be new types of helix-turn-helix DNA-binding domains. We term the new domains nuclease-associated modular DNA-binding domains (NUMODs).}, address = {Molecular Genetics Department, Weizmann Institute of Science, PO Box 26, Rehovot 76100, Israel.}, author = {Sitbon, E. and Pietrokovski, S. }, citeulike-article-id = {456125}, issn = {0968-0004}, journal = {Trends Biochem Sci}, keywords = {dna-binding, homing-endonuclease, motifs, msa, server}, month = {September}, number = {9}, pages = {473--477}, posted-at = {2006-01-05 09:17:56}, priority = {0}, title = {New types of conserved sequence domains in DNA-binding regions of homing endonucleases.}, url = {http://view.ncbi.nlm.nih.gov/pubmed/13678957}, volume = {28}, year = {2003} }

TY - JOUR ID - citeulike:456125 L3 - citeulike-article-id:456125 N2 - We have identified four new types of short conserved sequence domains in homing endonucleases and related proteins. These domains are modular, appearing in various combinations. One domain includes a motif known by structure as a novel sequence-specific DNA-binding helix. Sequence similarity shows two other domains to be new types of helix-turn-helix DNA-binding domains. We term the new domains nuclease-associated modular DNA-binding domains (NUMODs). IS - 9 JF - Trends Biochem Sci SN - 0968-0004 AD - Molecular Genetics Department, Weizmann Institute of Science, PO Box 26, Rehovot 76100, Israel. EP - 477 TI - New types of conserved sequence domains in DNA-binding regions of homing endonucleases. VL - 28 SP - 473 KW - dna-binding KW - homing-endonuclease KW - motifs KW - msa KW - server AU - Sitbon, E AU - Pietrokovski, S PY - 2003/09// UR - http://view.ncbi.nlm.nih.gov/pubmed/13678957 ER -