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Group: biomedical-nlp - with tag comps [63 articles]

Neue Artikel von Mitliedern der Gruppe biomedical-nlp Gruppe with tag comps
  • Using information theory to search for co-evolving residues in proteins.
    Bioinformatics, Vol. 21, No. 22. (15 November 2005), pp. 4116-4124.
    by LC Martin, GB Gloor, SD Dunn, LM Wahl
  • FlyBase: anatomical data, images and queries.
    Nucleic Acids Res, Vol. 34, No. Database issue. (1 January 2006)
    posted to comps database genomics major-proposal by caporaso to the group biomedical-nlp on 2006-11-28 23:20:33 as ** along with 1 person cmor
  • MUSCLE: a multiple sequence alignment method with reduced time and space complexity.
    BMC Bioinformatics, Vol. 5, No. 1. (19 August 2004)
    by RC Edgar
  • Residue coevolution: Modeling and interpretation
    (August 2006)
    by Zhengyuan Wang
    posted to coevolution compensatory comps major-proposal by caporaso to the group biomedical-nlp on 2006-11-11 00:44:42 as *****
  • Sarcomeric Proteins and Familial Hypertrophic Cardiomyopathy: Linking Mutations in Structural Proteins to Complex Cardiovascular Phenotypes
    Heart Failure Reviews, Vol. 10, No. 3. (September 2005), pp. 237-248.
    by Jil Tardiff
    posted to comps major-proposal myosin by caporaso to the group biomedical-nlp on 2006-11-11 00:39:35 as *****
  • Comparing genomes in terms of protein structure: surveys of a finite parts list.
    FEMS Microbiol Rev, Vol. 22, No. 4. (October 1998), pp. 277-304.
    by M Gerstein, H Hegyi
    posted to comps evolution major-proposal protein by caporaso to the group biomedical-nlp on 2006-09-23 01:40:45 as *****
  • Global mapping of pharmacological space
    Nature Biotechnology, Vol. 24, No. 7. (13 July 2006), pp. 805-815.
    by Gaia V Paolini, Richard HB Shapland, Willem P van Hoorn, Jonathan S Mason, Andrew L Hopkins
  • Studying Genomes Through the Aeons: Protein Families, Pseudogenes and Proteome Evolution
    Journal of Molecular Biology, Vol. 318, No. 5. (17 May 2002), pp. 1155-1174.
    by Paul M Harrison, Mark Gerstein
    posted to comps evolution major-proposal protein structural-biology by caporaso to the group biomedical-nlp on 2006-09-22 16:55:21 as read
  • CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice.
    Nucleic Acids Res, Vol. 22, No. 22. (11 November 1994), pp. 4673-4680.
    by JD Thompson, DG Higgins, TJ Gibson
  • Multiple sequence alignment
    Current Opinion in Structural Biology, Vol. 16, No. 3. (June 2006), pp. 368-373.
    by Robert C Edgar, Serafim Batzoglou
  • Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements
    Nucl. Acids Res., Vol. 29, No. 14. (15 July 2001), pp. 2994-3005.
    by Alejandro A Schaffer, L Aravind, Thomas L Madden, Sergei Shavirin, John L Spouge, Yuri I Wolf, Eugene V Koonin, Stephen F Altschul
    posted to alignment comps major-proposal sequence by caporaso to the group biomedical-nlp on 2006-09-19 18:01:22 as *****
  • Structural determinants of allosteric ligand activation in RXR heterodimers.
    Cell, Vol. 116, No. 3. (6 February 2004), pp. 417-429.
  • Allosteric determinants in guanine nucleotide-binding proteins.
    Proc Natl Acad Sci U S A, Vol. 100, No. 24. (25 November 2003), pp. 14445-14450.
    by ME Hatley, SW Lockless, SK Gibson, AG Gilman, R Ranganathan
  • Characterization of disease-associated single amino acid polymorphisms in terms of sequence and structure properties.
    J Mol Biol, Vol. 315, No. 4. (25 January 2002), pp. 771-786.
  • PMUT: a web-based tool for the annotation of pathological mutations on proteins
    Bioinformatics, Vol. 21, No. 14. (15 July 2005), pp. 3176-3178.
    by Carles Ferrer-Costa, Josep L Gelpi, Leire Zamakola, Ivan Parraga, de La, Modesto Orozco
  • Deleterious mutation prediction in the secondary structure of RNAs
    Nucl. Acids Res., Vol. 31, No. 22. (15 November 2003), pp. 6578-6584.
    by Danny Barash
    posted to comps function major-proposal rna structure by caporaso to the group biomedical-nlp on 2006-09-13 18:50:36 as *****
  • Prediction of deleterious human alleles.
    Hum Mol Genet, Vol. 10, No. 6. (15 March 2001), pp. 591-597.
    by S Sunyaev, V Ramensky, I Koch, W Lathe, AS Kondrashov, P Bork
  • Predicting the Effects of Amino Acid Substitutions on Protein Function.
    Annu Rev Genomics Hum Genet (9 August 2005)
    by Pauline C C Ng, Steven Henikoff
  • Predicting the functional consequences of non-synonymous single nucleotide polymorphisms: structure-based assessment of amino acid variation.
    J Mol Biol, Vol. 307, No. 2. (23 March 2001), pp. 683-706.
    by D Chasman, RM Adams
    posted to comps function major-proposal by caporaso to the group biomedical-nlp on 2006-09-13 01:53:59 as ***** along with 2 people chrn chad_davis
  • The impact of structural genomics on the protein data bank.
    Am J Pharmacogenomics, Vol. 4, No. 4. (2004), pp. 247-252.
    by HM Berman, JD Westbrook
    posted to comps major-proposal pdb structural-genomics-consortium by caporaso to the group biomedical-nlp on 2006-09-13 01:53:19 as *****
  • SNPeffect v2.0: a new step in investigating the molecular phenotypic effects of human non synonymous SNPs.
    Bioinformatics (29 June 2006)
    by Joke Reumers, Sebastian Maurer-Stroh, Joost Schymkowitz, Frederic Rousseau
  • The challenge of documenting mutation across the genome: the human genome variation society approach.
    Hum Mutat, Vol. 23, No. 5. (May 2004), pp. 447-452.
    by O Horaitis, RG Cotton
    posted to comps database major-proposal mutation by caporaso to the group biomedical-nlp on 2006-09-12 18:01:19 as read along with 1 person snuppepuppan
  • Protein structure database search and evolutionary classification.
    Nucleic Acids Res, Vol. 34, No. 13. (2006), pp. 3646-3659.
    by JM Yang, CH Tung
  • Integration of structural and functional genomics
    Animal Genetics, Vol. 37, No. s1. (2006), pp. 1-6.
    by CK Tuggle, JCM Dekkers, JM Reecy
  • The developing art of protein crystallisation: new advances from improved knowledge automation and miniaturisation.
    Prog Biophys Mol Biol, Vol. 88, No. 3. (July 2005), pp. 283-284.
    by TL Blundell
    posted to comps major-proposal structural-biology by caporaso to the group biomedical-nlp on 2006-09-11 03:23:52 as read
  • Application of NMR screening in drug discovery.
    Curr Top Med Chem, Vol. 3, No. 1. (2003), pp. 81-97.
    by J Fejzo, C Lepre, X Xie
  • NMR-based screening in drug discovery.
    Q Rev Biophys, Vol. 32, No. 3. (August 1999), pp. 211-240.
    by PJ Hajduk, RP Meadows, SW Fesik
    posted to comps drug-design druggability minor-proposal screening by caporaso to the group biomedical-nlp on 2006-09-10 23:29:36 as *****
  • Discovering high-affinity ligands for proteins: SAR by NMR.
    Science, Vol. 274, No. 5292. (29 November 1996), pp. 1531-1534.
    by SB Shuker, PJ Hajduk, RP Meadows, SW Fesik
  • Latest developments in crystallography and structure-based design of protein kinase inhibitors as drug candidates.
    Curr Opin Pharmacol, Vol. 2, No. 5. (October 2002), pp. 567-573.
    posted to comps drug-design druggability minor-proposal by caporaso to the group biomedical-nlp on 2006-09-10 23:02:27 as ***
  • Target analysis: a priori assessment of druggability.
    Ernst Schering Res Found Workshop, No. 42. (2003), pp. 11-17.
    by AL Hopkins, CR Groom
    posted to comps drug-design druggability minor-proposal protein by caporaso to the group biomedical-nlp on 2006-09-10 23:01:05 as ****
  • From target identification to drug screening assays for neurodegenerative diseases.
    Pharmacol Res, Vol. 52, No. 3. (September 2005), pp. 245-251.
    posted to comps druggability minor-proposal screening by caporaso to the group biomedical-nlp on 2006-09-10 22:57:26 as ***
  • Druggability: selecting optimized drug candidates.
    Drug Discov Today, Vol. 10, No. 23-24. (December 2005), pp. 1577-1579.
    posted to comps drug-design druggability minor-proposal by caporaso to the group biomedical-nlp on 2006-09-10 22:51:58 as ****
  • Progress and problems in the exploration of therapeutic targets.
    Drug Discov Today, Vol. 11, No. 9-10. (May 2006), pp. 412-420.
    by C Zheng, L Han, CW Yap, B Xie, Y Chen
    posted to comps drug-design druggability minor-proposal by caporaso to the group biomedical-nlp on 2006-09-10 22:45:10 as *****
  • Modern biomedical research: an internally self-consistent universe with little contact with medical reality?
    Nat Rev Drug Discov, Vol. 2, No. 2. (February 2003), pp. 151-154.
    by DF Horrobin
  • Chemoinformatics - predicting the physicochemical properties of 'drug-like' molecules.
    Curr Opin Biotechnol, Vol. 11, No. 1. (February 2000), pp. 104-107.
    by JF Blake
    posted to comps data-mining drug-design druggability minor-proposal screening by caporaso to the group biomedical-nlp on 2006-09-10 19:24:26 as ****
  • Binding MOAD (Mother Of All Databases).
    Proteins (21 June 2005)
    by Liegi Hu, Mark L L Benson, Richard D D Smith, Michael G G Lerner, Heather A A Carlson
  • A Novel Method for Detecting Intramolecular Coevolution: Adding a Further Dimension to Selective Constraints Analyses
    Genetics, Vol. 173, No. 1. (1 May 2006), pp. 9-23.
    by Mario A Fares, Simon A Travers
  • Anti-SARS drug screening by molecular docking.
    Amino Acids, Vol. 31, No. 1. (July 2006), pp. 73-80.
    by DQ Wei, R Zhang, QS Du, WN Gao, Y Li, H Gao, SQ Wang, X Zhang, AX Li, S Sirois, KC Chou
    posted to comps drug-design druggability minor-proposal screening by caporaso to the group biomedical-nlp on 2006-09-07 16:21:44 as *****
  • A cell-based ultra-high-throughput screening assay for identifying inhibitors of D-amino acid oxidase.
    J Biomol Screen, Vol. 11, No. 5. (August 2006), pp. 481-487.
  • Prediction of the phenotypic effects of non-synonymous single nucleotide polymorphisms using structural and evolutionary information.
    Bioinformatics, Vol. 21, No. 10. (15 May 2005), pp. 2185-2190.
    by L Bao, Y Cui
  • Lead- and drug-like compounds: the rule-of-five revolution
    Drug Discovery Today: Technologies, Vol. 1, No. 4. (December 2004), pp. 337-341.
    by Christopher A Lipinski
  • Druggability indices for protein targets derived from NMR-based screening data.
    J Med Chem, Vol. 48, No. 7. (7 April 2005), pp. 2518-2525.
    by PJ Hajduk, JR Huth, SW Fesik
  • Discovery of a potent inhibitor of the antiapoptotic protein Bcl-xL from NMR and parallel synthesis.
    J Med Chem, Vol. 49, No. 2. (26 January 2006), pp. 656-663.
    by AM Petros, J Dinges, DJ Augeri, SA Baumeister, DA Betebenner, MG Bures, SW Elmore, PJ Hajduk, MK Joseph, SK Landis, DG Nettesheim, SH Rosenberg, W Shen, S Thomas, X Wang, I Zanze, H Zhang, SW Fesik
    posted to comps drug-design druggability minor-proposal screening structural-biology by caporaso to the group biomedical-nlp on 2006-09-05 20:42:01 as ****
  • From fold predictions to function predictions: automation of functional site conservation analysis for functional genome predictions.
    Protein Sci, Vol. 8, No. 5. (May 1999), pp. 1104-1115.
  • Statistically rigorous automated protein annotation.
    Bioinformatics, Vol. 20, No. 7. (1 May 2004), pp. 1066-1073.
    by WG Krebs, PE Bourne
    posted to compare comps function major-proposal mutation protein structural-biology by caporaso to the group biomedical-nlp on 2006-09-02 01:26:20 as *****
  • Statistical and visual morph movie analysis of crystallographic mutant selection bias in protein mutation resource data.
    J Bioinform Comput Biol, Vol. 2, No. 1. (March 2004), pp. 61-75.
    by WG Krebs, PE Bourne
    posted to compare comps data-mining major-proposal mutation protein structural-biology by caporaso to the group biomedical-nlp on 2006-09-02 01:24:29 as read
  • Statistical and visual morph movie analysis of crystallographic mutant selection bias in protein mutation resource data.
    Proc IEEE Comput Soc Bioinform Conf, Vol. 2 (2003), pp. 180-189.
    by WG Krebs, PE Bourne
  • MutaProt: a web interface for structural analysis of point mutations.
    Bioinformatics, Vol. 17, No. 4. (April 2001), pp. 381-382.
  • Clustering of highly homologous sequences to reduce the size of large protein databases.
    Bioinformatics, Vol. 17, No. 3. (March 2001), pp. 282-283.
    by W Li, L Jaroszewski, A Godzik
    posted to clustering comps major-proposal protein sequence by caporaso to the group biomedical-nlp on 2006-09-01 22:00:52 as read along with 1 person Cortel
  • MSDsite: A database search and retrieval system for the analysis and viewing of bound ligands and active sites
    Proteins: Structure, Function, and Bioinformatics, Vol. 58, No. 1. (2005), pp. 190-199.
    by Adel Golovin, Dimitris Dimitropoulos, Tom Oldfield, Abdelkrim Rachedi, Kim Henrick
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