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Autor Hirschhorn [34 articles]

Neu eingetragene Papers vom Autor: Hirschhorn.
  • A comprehensive review of genetic association studies.
    Genet Med, Vol. 4, No. 2. (r 2002), pp. 45-61.
    posted to genetics by applebyb on 2008-06-21 12:46:41 as ***** along with 1 person mrkrause
  • Genome-wide association studies for complex traits: consensus, uncertainty and challenges
    Nature Reviews Genetics, Vol. 9, No. 5., pp. 356-369.
    by Mark I Mccarthy, Gonçalo R Abecasis, Lon R Cardon, David B Goldstein, Julian Little, John PA Ioannidis, Joel N Hirschhorn
  • Evaluation of common variants in the six known maturity-onset diabetes of the young (MODY) genes for association with type 2 diabetes.
    Diabetes, Vol. 56, No. 3. (March 2007), pp. 685-693.
    posted to postdocs by jasonflannick on 2008-06-12 03:36:39 as **
  • Genome-Wide Association Analysis Identifies Loci for Type 2 Diabetes and Triglyceride Levels.
    Science (26 April 2007)
    by Richa Saxena, Benjamin F F Voight, Valeriya Lyssenko, Noel P P Burtt, Paul I W I de Bakker, Hong Chen, Jeffrey J J Roix, Sekar Kathiresan, Joel N N Hirschhorn, Mark J J Daly, Thomas E E Hughes, Leif Groop, David Altshuler, Peter Almgren, Jose C C Florez, Joanne Meyer, Kristin Ardlie, Kristina Bengtsson, Bo Isomaa, Guillaume Lettre, Ulf Lindblad, Helen N N Lyon, Olle Melander, Christopher Newton-Cheh, Peter Nilsson, Marju Orho-Melander, Lennart Råstam, Elizabeth K K Speliotes, Marja-Riitta R Taskinen, Tiinamaija Tuomi, Candace Guiducci, Anna Berglund, Joyce Carlson, Lauren Gianniny, Rachel Hackett, Liselott Hall, Johan Holmkvist, Esa Laurila, Marketa Sjögren, Maria Sterner, Aarti Surti, Margareta Svensson, Malin Svensson, Ryan Tewhey, Brendan Blumenstiel, Melissa Parkin, Matthew Defelice, Rachel Barry, Wendy Brodeur, Jody Camarata, Nancy Chia, Mary Fava, John Gibbons, Bob Handsaker, Claire Healy, Kieu Nguyen, Casey Gates, Carrie Sougnez, Diane Gage, Marcia Nizzari, Stacey B B Gabriel, Gung-Wei W Chirn, Qicheng Ma, Hemang Parikh, Delwood Richardson, Darrell Ricke, Shaun Purcell
  • PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes.
    Nat Genet, Vol. 34, No. 3. (July 2003), pp. 267-273.
  • On the replication of genetic associations: timing can be everything!
    American journal of human genetics, Vol. 82, No. 4. (April 2008), pp. 849-858.
    posted to no-tag by jyuh on 2008-05-09 03:56:14 as **
  • Common variants near MC4R are associated with fat mass, weight and risk of obesity.
    Nature genetics (4 May 2008)
    by Ruth J F J Loos, Cecilia M M Lindgren, Shengxu Li, Eleanor Wheeler, Jing Hua H Zhao, Inga Prokopenko, Michael Inouye, Rachel M M Freathy, Antony P P Attwood, Jacques S S Beckmann, Sonja I I Berndt, , Kevin B B Jacobs, Stephen J J Chanock, Richard B B Hayes, Sven Bergmann, Amanda J J Bennett, Sheila A A Bingham, Murielle Bochud, Morris Brown, Stéphane Cauchi, John M M Connell, Cyrus Cooper, George Davey D Smith, Ian Day, Christian Dina, Subhajyoti De, Emmanouil T T Dermitzakis, Alex S F S Doney, Katherine S S Elliott, Paul Elliott, David M M Evans, I Sadaf Farooqi, Philippe Froguel, Jilur Ghori, Christopher J J Groves, Rhian Gwilliam, David Hadley, Alistair S S Hall, Andrew T T Hattersley, Johannes Hebebrand, Iris M M Heid, , Claudia Lamina, Christian Gieger, Thomas Illig, Thomas Meitinger, H-Erich E Wichmann, Blanca Herrera, Anke Hinney, Sarah E E Hunt, Marjo-Riitta R Jarvelin, Toby Johnson, Jennifer D M D Jolley, Fredrik Karpe, Andrew Keniry, Kay-Tee T Khaw, Robert N N Luben, Massimo Mangino, Jonathan Marchini, Wendy L L McArdle, Ralph McGinnis, David Meyre, Patricia B B Munroe, Andrew D D Morris, Andrew R R Ness, Matthew J J Neville, Alexandra C C Nica, Ken K K Ong, Stephen O'Rahilly, Katharine R R Owen, Colin N A N Palmer, Konstantinos Papadakis, Simon Potter, Anneli Pouta, Lu Qi, , Peter Kraft, Susan E E Hankinson, David J J Hunter, Frank B B Hu, Joshua C C Randall, Nigel W W Rayner, Susan M M Ring, Manjinder S S Sandhu, André Scherag, Matthew A A Sims, Kijoung Song, Nicole Soranzo, Elizabeth K K Speliotes, , Helen N N Lyon, Benjamin F F Voight, Martin Ridderstrale, Leif Groop, Holly E E Syddall, Sarah A A Teichmann, Nicholas J J Timpson, Jonathan H H Tobias, Manuela Uda, , Paul Scheet, Serena Sanna, Goncalo R R Abecasis, Giuseppe Albai, Ramaiah Nagaraja, David Schlessinger, Carla I I Ganz Vogel, Chris Wallace, Dawn M M Waterworth, Michael N N Weedon, , Cristen J J Willer, , Anne U U Jackson, Jaakko Tuomilehto, Francis S S Collins, Michael Boehnke, Karen L L Mohlke, Vicki L L Wraight, Xin Yuan, Eleftheria Zeggini, Joel N N Hirschhorn, David P P Strachan, Willem H H Ouwehand, Mark J J Caulfield, Nilesh J J Samani, Timothy M M Frayling, Peter Vollenweider, Gerard Waeber, Vincent Mooser, Panos Deloukas, Mark I I McCarthy, Nicholas J J Wareham, Inês Barroso
    posted to no-tag by Terkko on 2008-05-07 09:46:27 as **
  • Identification of ten loci associated with height highlights new biological pathways in human growth.
    Nature genetics (6 April 2008)
    by Guillaume Lettre, Anne U U Jackson, Christian Gieger, Fredrick R R Schumacher, Sonja I I Berndt, Serena Sanna, Susana Eyheramendy, Benjamin F F Voight, Johannah L L Butler, Candace Guiducci, Thomas Illig, Rachel Hackett, Iris M M Heid, Kevin B B Jacobs, Valeriya Lyssenko, Manuela Uda, , , , , , , Michael Boehnke, Stephen J J Chanock, Leif C C Groop, Frank B B Hu, Bo Isomaa, Peter Kraft, Leena Peltonen, Veikko Salomaa, David Schlessinger, David J J Hunter, Richard B B Hayes, Gonçalo R R Abecasis, H-Erich E Wichmann, Karen L L Mohlke, Joel N N Hirschhorn
    posted to gwas by caseybrown on 2008-04-28 22:55:06 as read along with 1 person Terkko
  • A survey of allelic imbalance in F1 mice
    Genome Res., Vol. 18, No. 4. (1 April 2008), pp. 555-563.
    by Catarina D Campbell, Andrew Kirby, James Nemesh, Mark J Daly, Joel N Hirschhorn
    posted to mouse expression allelic by mimulus_99 on 2008-04-23 16:22:08 as read along with 1 person caseybrown
  • notes Polymorphisms Associated with Cholesterol and Risk of Cardiovascular Events
    N Engl J Med, Vol. 358, No. 12. (20 March 2008), pp. 1240-1249.
    by Sekar Kathiresan, Olle Melander, Dragi Anevski, Candace Guiducci, Noel P Burtt, Charlotta Roos, Joel N Hirschhorn, Goran Berglund, Bo Hedblad, Leif Groop, David M Altshuler, Christopher Newton-Cheh, Marju Orho-Melander
    posted to genetic hplp molecular risk by omalbam on 2008-04-15 21:24:41 as ** along with 1 person kochhan
  • A common variant of HMGA2 is associated with adult and childhood height in the general population.
    Nat Genetics, Vol. 39 (2 September 2007), pp. 1245-1250.
    by Michael NN Weedon, Guillaume Lettre, Rachel MM Freathy, Cecilia MM Lindgren, Benjamin FF Voight, John RBR Perry, Katherine SS Elliott, Rachel Hackett, Candace Guiducci, Beverley Shields, Eleftheria Zeggini, Hana Lango, Valeriya Lyssenko, Nicholas JJ Timpson, Noel PP Burtt, Nigel WW Rayner, Richa Saxena, Kristin Ardlie, Jonathan HH Tobias, Andrew RR Ness, Susan MM Ring, Colin NAN Palmer, Andrew DD Morris, Leena Peltonen, Veikko Salomaa, George, Leif CC Groop, Andrew TT Hattersley, Mark II Mccarthy, Joel NN Hirschhorn, Timothy MM Frayling
    posted to o3-paper by natstreet on 2008-03-17 15:23:38 as ** along with 2 people Terkko dchughes
  • Discerning the Ancestry of European Americans in Genetic Association Studies
    PLoS Genetics, Vol. 4, No. 1. (1 January 2008), e236.
    by Alkes L Price, Johannah Butler, Nick Patterson, Cristian Capelli, Vincenzo L Pascali, Francesca Scarnicci, Andres Ruiz-Linares, Leif Groop, Angelica A Saetta, Penelope Korkolopoulou, Uri Seligsohn, Alicja Waliszewska, Christine Schirmer, Kristin Ardlie, Alexis Ramos, James Nemesh, Lori Arbeitman, David B Goldstein, David Reich, Joel N Hirschhorn
  • Transferability of tag SNPs in genetic association studies in multiple populations
    Nature Genetics, Vol. 38, No. 11. (22 October 2006), pp. 1298-1303.
    by Paul IW de Bakker, Noël P Burtt, Robert R Graham, Candace Guiducci, Roman Yelensky, Jared A Drake, Todd Bersaglieri, Kathryn L Penney, Johannah Butler, Stanton Young, Robert C Onofrio, Helen N Lyon, Daniel O Stram, Christopher A Haiman, Matthew L Freedman, Xiaofeng Zhu, Richard Cooper, Leif Groop, Laurence N Kolonel, Brian E Henderson, Mark J Daly, Joel N Hirschhorn, David Altshuler
  • Common variants in the GDF5-UQCC region are associated with variation in human height.
    Nat Genet (13 January 2008)
    by Serena Sanna, Anne U U Jackson, Ramaiah Nagaraja, Cristen J J Willer, Wei-Min M Chen, Lori L L Bonnycastle, Haiqing Shen, Nicholas Timpson, Guillaume Lettre, Gianluca Usala, Peter S S Chines, Heather M M Stringham, Laura J J Scott, Mariano Dei, Sandra Lai, Giuseppe Albai, Laura Crisponi, Silvia Naitza, Kimberly F F Doheny, Elizabeth W W Pugh, Yoav Ben-Shlomo, Shah Ebrahim, Debbie A A Lawlor, Richard N N Bergman, Richard M M Watanabe, Manuela Uda, Jaakko Tuomilehto, Josef Coresh, Joel N N Hirschhorn, Alan R R Shuldiner, David Schlessinger, Francis S S Collins, George Davey D Smith, Eric Boerwinkle, Antonio Cao, Michael Boehnke, Gonçalo R R Abecasis, Karen L L Mohlke
    posted to no-tag by Terkko on 2008-01-16 10:53:02 as **
  • Genetic signatures of strong recent positive selection at the lactase gene.
    Am J Hum Genet, Vol. 74, No. 6. (June 2004), pp. 1111-1120.
    posted to diet evolution genetics lactase by brian to the group Fasting, food and evolution on 2007-12-11 19:30:48 as ** along with 1 person balicea
  • Heritability, linkage, and genetic associations of exercise treadmill test responses.
    Circulation, Vol. 115, No. 23. (12 June 2007), pp. 2917-2924.
    posted to no-tag by jyuh on 2007-11-28 15:55:33 as **
  • Discerning the ancestry of European Americans in genetic association studies
    PLoS Genetics, Vol. preprint, No. 2007. (1 November 2007), e236.eor.
    by Alkes Price, Johannah L Butler, Nick Patterson, Cristian Capelli, Vincenzo L Pascali, Francesca Scarnicci, Andres Ruiz-Linares, Leif C Groop, Angelica A Saetta, Penelope Korkolopoulou, Uri Seligsohn, Alicja Waliszewska, Christine Schirmer, Kristin Ardlie, Alexis Ramos, James Nemesh, Lori Arbeitman, David B Goldstein, David Reich, Joel Hirschhorn
    posted to ancestry to-review update-when-final by ryanraaum on 2007-11-26 13:19:27 as **
  • Discerning the ancestry of European Americans in genetic association studies
    PLoS Genetics, Vol. preprint, No. 2007. (1 November 2007), e236.eor.
    by Alkes Price, Johannah L Butler, Nick Patterson, Cristian Capelli, Vincenzo L Pascali, Francesca Scarnicci, Andres Ruiz-Linares, Leif C Groop, Angelica A Saetta, Penelope Korkolopoulou, Uri Seligsohn, Alicja Waliszewska, Christine Schirmer, Kristin Ardlie, Alexis Ramos, James Nemesh, Lori Arbeitman, David B Goldstein, David Reich, Joel Hirschhorn
    posted to association popgen snps by djkt on 2007-11-23 20:26:59 as **
  • Choosing haplotype-tagging SNPS based on unphased genotype data using a preliminary sample of unrelated subjects with an example from the Multiethnic Cohort Study.
    Hum Hered, Vol. 55, No. 1. (2003), pp. 27-36.
    by DO Stram, CA Haiman, JN Hirschhorn, D Altshuler, LN Kolonel, BE Henderson, MC Pike
    posted to mec tag-snps unphased by StatAnika on 2007-11-22 16:03:45 as read
  • Modeling and E-M estimation of haplotype-specific relative risks from genotype data for a case-control study of unrelated individuals.
    Hum Hered, Vol. 55, No. 4. (2003), pp. 179-190.
    posted to haplotypes imputation tag-snps by StatAnika on 2007-11-22 16:01:57 as read
  • Conserved noncoding sequences are selectively constrained and not mutation cold spots
    Nature Genetics, Vol. 38, No. 2. (25 December 2005), pp. 223-227.
    by Jared A Drake, Christine Bird, James Nemesh, Daryl J Thomas, Christopher Newton-Cheh, Alexandre Reymond, Laurent Excoffier, Homa Attar, Stylianos E Antonarakis, Emmanouil T Dermitzakis, Joel N Hirschhorn
  • Demonstrating stratification in a European American population
    Nature Genetics, Vol. 37, No. 8. (24 July 2005), pp. 868-872.
    by Catarina D Campbell, Elizabeth L Ogburn, Kathryn L Lunetta, Helen N Lyon, Matthew L Freedman, Leif C Groop, David Altshuler, Kristin G Ardlie, Joel N Hirschhorn
    posted to assignment association structure by ryanraaum on 2007-10-18 17:35:25 as ** along with 1 person sriram_s
  • Detection of regulatory variation in mouse genes
    Nat Genet, Vol. 32, No. 3. (November 2002), pp. 432-437.
    by Christopher R Cowles, Joel N Hirschhorn, David Altshuler, Eric S Lander
    posted to allelic expression mouse survey by mimulus_99 on 2007-09-24 22:04:58 as ***
  • Replicating genotypeâphenotype associations
    Nature, Vol. 447, No. 7145. (06 June 2007), pp. 655-660.
    by Stephen J Chanock, Teri Manolio, Michael Boehnke, Eric Boerwinkle, David J Hunter, Gilles Thomas, Joel N Hirschhorn, Goncalo Abecasis, David Altshuler, Joan E Bailey-Wilson, Lisa D Brooks, Lon R Cardon, Mark Daly, Peter Donnelly, Joseph F Fraumeni, Nelson B Freimer, Daniela S Gerhard, Chris Gunter, Alan E Guttmacher, Mark S Guyer, Emily L Harris, Josephine Hoh, Robert Hoover, Augustine C Kong, Kathleen R Merikangas, Cynthia C Morton, Lyle J Palmer, Elizabeth G Phimister, John P Rice, Jerry Roberts, Charles Rotimi, Margaret A Tucker, Kyle J Vogan, Sholom Wacholder, Ellen M Wijsman, Deborah M Winn, Francis S Collins
    posted to no-tag by jyuh on 2007-09-19 07:17:35 as ** along with 1 person farhat
  • Genome-wide association studies for common diseases and complex traits
    Nature Reviews Genetics, Vol. 6, No. 2. (01 February 2005), pp. 95-108.
    by Joel N Hirschhorn, Mark J Daly
  • Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease
    Nat Genet, Vol. 33, No. 2. (February 2003), pp. 177-182.
    by Kirk E Lohmueller, Celeste L Pearce, Malcolm Pike, Eric S Lander, Joel N Hirschhorn
    posted to no-tag by sriram_s on 2007-08-16 02:31:21 as **
  • Investigation of the estrogen receptor-alpha gene with type 2 diabetes and/or nephropathy in African-American and European-American populations.
    Diabetes, Vol. 56, No. 3. (March 2007), pp. 675-684.
    by CJ Gallagher, KL Keene, JC Mychaleckyj, CD Langefeld, JN Hirschhorn, BE Henderson, CJ Gordon, BI Freedman, SS Rich, DW Bowden, MM Sale
    posted to no-tag by jyuh on 2007-06-23 03:21:05 as **
  • A common genetic variant in the NOS1 regulator NOS1AP modulates cardiac repolarization
    Nature Genetics, Vol. 38, No. 6. (30 April 2006), pp. 644-651.
    by Dan E Arking, Arne Pfeufer, Wendy Post, Linda WH Kao, Christopher Newton-Cheh, Morna Ikeda, Kristen West, Carl Kashuk, Mahmut Akyol, Siegfried Perz, Shapour Jalilzadeh, Thomas Illig, Christian Gieger, Chao-Yu Guo, Martin G Larson, Erich H Wichmann, Eduardo Marbán, Christopher J O'Donnell, Joel N Hirschhorn, Stefan Kääb, Peter M Spooner, Thomas Meitinger, Aravinda Chakravarti
    posted to association disease genome heart interval qt wide by joepickrell on 2007-05-27 21:06:36 as **
  • The Association of a SNP Upstream of INSIG2 with Body Mass Index is Reproduced in Several but Not All Cohorts
    PLoS Genetics, Vol. 3, No. 4. (1 April 2007), e61.
    by Helen N Lyon, Valur Emilsson, Anke Hinney, Iris M Heid, Jessica Lasky-Su, Xiaofeng Zhu, Gudmar Thorleifsson, Steinunn Gunnarsdottir, Bragi G Walters, Unnur Thorsteinsdottir, Augustine Kong, Jeffrey Gulcher, Thuy T Nguyen, André Scherag, Arne Pfeufer, Thomas Meitinger, Günter Brönner, Winfried Rief, Manuel E Soto-Quiros, Lydiana Avila, Barbara Klanderman, Benjamin A Raby, Edwin K Silverman, Scott T Weiss, Nan Laird, Xiao Ding, Leif Groop, Tiinamaija Tuomi, Bo Isomaa, Kristina Bengtsson, Johannah L Butler, Richard S Cooper, Caroline S Fox, Christopher J O'Donnell, Caren Vollmert, Juan C Celedón, Erich H Wichmann, Johannes Hebebrand, Kari Stefansson, Christoph Lange, Joel N Hirschhorn
    posted to association genome obesity wide by joepickrell on 2007-05-27 21:05:22 as **
  • A Common Genetic Variant Is Associated with Adult and Childhood Obesity
    Science, Vol. 312, No. 5771. (14 April 2006), pp. 279-283.
    by Alan Herbert, Norman P Gerry, Matthew B Mcqueen, Iris M Heid, Arne Pfeufer, Thomas Illig, Wichmann, Thomas Meitinger, David Hunter, Frank B Hu, Graham Colditz, Anke Hinney, Johannes Hebebrand, Kerstin Koberwitz, Xiaofeng Zhu, Richard Cooper, Kristin Ardlie, Helen Lyon, Joel N Hirschhorn, Nan M Laird, Marc E Lenburg, Christoph Lange, Michael F Christman
  • Comprehensive association testing of common mitochondrial DNA variation in metabolic disease.
    Am J Hum Genet, Vol. 79, No. 1. (July 2006), pp. 54-61.
    by R Saxena, PI de Bakker, K Singer, V Mootha, N Burtt, JN Hirschhorn, D Gaudet, B Isomaa, MJ Daly, L Groop, KG Ardlie, D Altshuler
  • Huntingtin phosphorylation sites mapped by mass spectrometry. Modulation of cleavage and toxicity.
    J Biol Chem, Vol. 281, No. 33. (18 August 2006), pp. 23686-23697.
  • Duty to re-contact.
    Genet Med, Vol. 1, No. 4. (n 1999), pp. 171-172.
  • notes Systematic Evaluation of Genetic Variation at the Androgen Receptor Locus and Risk of Prostate Cancer in a Multiethnic Cohort Study.
    Am J Hum Genet, Vol. 76, No. 1. (29 November 2004)
    by Matthew L L Freedman, Celeste L L Pearce, Kathryn L L Penney, Joel N N Hirschhorn, Laurence N N Kolonel, Brian E E Henderson, David Altshuler
    posted to test by dervink on 2004-12-01 20:55:37
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