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Membrane nanotubes: dynamic long-distance connections between animal cells

by: Daniel M Davis, Stefanie Sowinski
Nature Reviews Molecular Cell Biology, Vol. 9, No. 6. (23 April 2008), pp. 431-436.

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Membrane nanotubes are transient long-distance connections between cells that can facilitate intercellular communication (for example, by trafficking vesicles or transmitting calcium-mediated signals), but they can also contribute to pathologies (for example, by directing the spread of viruses). Recent data have revealed considerable heterogeneity in their structures, processes of formation and functional properties, in part dependent on the cell types involved. Despite recent progress in this young research field, further research is sorely needed.


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